Talent.com
Global Commercial Director T2D, CVRM
Global Commercial Director T2D, CVRMAstraZeneca • Boston, MA, United States
Global Commercial Director T2D, CVRM

Global Commercial Director T2D, CVRM

AstraZeneca • Boston, MA, United States
21 days ago
Job type
  • Full-time
Job description

At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We’re focused on the potential of science to address the unmet needs of patients around the world. We commit to those areas where we think we can really change the course of medicine.

Within our BBU CVRM franchise, we’ve established a new commercial area focused on Weight Management and Type 2 Diabetes (T2D). Our ambition is to deliver a portfolio of simple, scalable, and sustainable solutions that improve health and wellbeing, reduce cardiometabolic risk and protect organs for people living with diabetes, overweight, and / or obesity.

To achieve this, we’re seeking an experienced commercial leader to shape the launch strategy for one of our lead assets in T2D and related cardiometabolic conditions. This is a pivotal pre-launch role that defines how we bring the science to market and prepare the organization for launch success.

The role reports to the Global Commercial Head Weight Management

Key Responsibilities

  • Lead development of a global go-to-market (GTM) strategy — including market segmentation, positioning, target audiences, and launch sequencing.
  • Translate strategic objectives into an actionable global pre-launch roadmap, defining the value proposition, brand narrative, and engagement approach.
  • Partner with regional and country commercial leaders to ensure global alignment and adaptability to local market realities.
  • Create and socialize a clear brand strategy that balances scientific differentiation with emotional resonance across key stakeholders (HCPs, payers, patients, advocacy).
  • Lead deep analysis of market dynamics, competitive environment, and evolving treatment paradigms to anticipate opportunities and risks.
  • Partner with Insights, Analytics & Forecasting teams to generate actionable market and customer insights that inform TPP design, clinical plans, and launch assumptions.
  • Develop and execute market-shaping initiatives — including awareness, disease-education, and early-access strategies — to create readiness ahead of launch.
  • Build external validation loops through advisory boards, stakeholder mapping, and co-creation with key opinion leaders and advocacy groups.
  • Partner closely with R&D, Clinical, Regulatory, Medical Affairs, Pricing & Market Access, and Global Product Teams to ensure the commercial voice is embedded early in development.
  • Align global functions around clear pre-launch milestones (e.g., TPP validation, pricing strategy, access readiness, global narrative, and launch framework).
  • Define and track KPIs to measure organizational readiness and strategic progress toward launch.
  • Collaborate with regional / country teams to ensure knowledge transfer, toolkit development, and capability building for first-wave markets.
  • Oversee creation of core global brand assets and messaging frameworks to ensure consistency across markets and channels.
  • Manage relationships with creative and strategic agencies, consultants, and other third-party partners to develop pre-launch materials and campaigns.
  • Lead development of the brand identity system — naming, tone of voice, and creative direction — in alignment with AstraZeneca standards and scientific integrity.
  • Serve as a key member of the Global Commercial Leadership Team, ensuring transparency of strategy, timelines, and investment decisions.
  • Present GTM recommendations, forecasts, and business cases to governance boards and senior leadership.
  • Foster strong collaboration across functions and geographies; champion a culture of curiosity, accountability, and evidence-based decision making.

Essential Skills / Experience

  • Bachelor’s degree required; advanced degree (MBA, PhD, or MSc) preferred.
  • 10+ years experience in pharmaceutical commercial strategy or marketing, ideally in pre-launch or early launch settings.
  • Relevant experience in TA : cardiometabolic, obesity, or T2D
  • Strong track record in developing and executing go-to-market or brand strategies that integrate insight generation, forecasting, and positioning.
  • Proven ability to collaborate across scientific, regulatory, and commercial interfaces to drive alignment.
  • Excellent analytical, strategic, and communication skills; comfortable influencing at senior levels in a matrixed environment.
  • Self-starter with high energy, intellectual curiosity, and the ability to lead through ambiguity
  • Desirable Skills

  • Experience in US or other large market
  • Previous experience in global role
  • Direct experience in market shaping, disease education, or pre-launch activation.
  • Strong working knowledge of pricing, reimbursement, and access strategy.
  • Familiarity with digital ecosystem development and omnichannel stakeholder engagement.
  • When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

    AstraZeneca offers an environment where diversity is our strength, reflecting the variety of patients we serve. Here, you'll find a place for continuous learning, exchanging knowledge, and building best practices to grow your career. With a fusion of support, trust, and agility, you'll be encouraged to bring your whole self to work and embrace all the investment, feedback, and ample opportunities on offer. It's an exciting time for our team as we redefine the future of healthcare.

    Ready to jump in and be part of something extraordinary? Apply now and take the next step in your career journey with AstraZeneca!

    The annual base pay for this position ranges from $229,303 to $343,955. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles),to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department / team performance, and market factors.

    Date Posted

    06-Nov-2025

    Closing Date

    19-Nov-2025

    Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

    #J-18808-Ljbffr

    Create a job alert for this search

    Director Commercial • Boston, MA, United States

    Related jobs
    Senior Manager, Business Development, Cell & Gene Therapies

    Senior Manager, Business Development, Cell & Gene Therapies

    Fresenius Kabi USA, LLC • North Andover, MA, United States
    Full-time
    The Senior Manager, Business Development, will play a critical role in driving global sales and business development strategy for our cutting-edge Cell and Gene Therapies (CGT) Technologies divisio...Show more
    Last updated: 30+ days ago • Promoted
    Director - Audit

    Director - Audit

    Gray Gray & Gray • Canton, MA, United States
    Full-time
    Gray, Gray & Gray is one of New England's fastest growing independent full-service consulting, accounting and advisory firms and we are looking for highly motivated, enthusiastic professionals who ...Show more
    Last updated: 20 days ago • Promoted
    Clinical Director of Practice : General Dentist

    Clinical Director of Practice : General Dentist

    42 NORTH DENTAL LLC • Brockton, MA, United States
    Full-time
    Why You ll Love this Clinical Dental Director Job!.Do you have excellent team building and leadership skills? If you 're able to work with our specialists to expand growth in specialty departments ...Show more
    Last updated: 30+ days ago • Promoted
    Director, Global Commercial Team, Rheumatology

    Director, Global Commercial Team, Rheumatology

    argenx • Boston, MA, United States
    Full-time
    Join us as we transform immunology and deliver medicines that help autoimmune patients get their lives back.VYVGART, our first‑in‑class neonatal Fc receptor blocker approved for the treatment of gM...Show more
    Last updated: 27 days ago • Promoted
    Business Development Director, Global Client Solutions

    Business Development Director, Global Client Solutions

    Cambridge Associates • Boston, MA, United States
    Full-time
    Business Development Director, Global Client Solutions.Cambridge Associates ("CA") is a leading global investment firm.CA’s goal is to help endowments & foundations, pension plans, and ultra‑high n...Show more
    Last updated: 9 days ago • Promoted
    Director, Clinical Quality Assurance

    Director, Clinical Quality Assurance

    Eisai • Andover, MA, United States
    Full-time
    At Eisai, satisfying unmet medical needs and increasing the benefits healthcare provides to patients, their families, and caregivers is Eisai's human health care (hhc) mission.We're a growing pharm...Show more
    Last updated: 30+ days ago • Promoted
    MA568x - Child Psychiatrist / Medical Director

    MA568x - Child Psychiatrist / Medical Director

    Fcs Co • Brockton, MA, United States
    Full-time
    Child Psychiatrist needed for a Medical Director role in at a multi-disciplinary behavioral health practice slightly east of Brocton. Competitive pay and flexible scheduling.In-person or Hybrid work...Show more
    Last updated: 30+ days ago • Promoted
    Senior Director, Global Commercial Strategy – CF Pipeline Lead

    Senior Director, Global Commercial Strategy – CF Pipeline Lead

    Vertex Pharmaceuticals (San Diego) LLC • Boston, MA, United States
    Full-time
    Job Description • •Vertex operates at the forefront of scientific innovation.It has seven approved medicines : five that treat the underlying cause of cystic fibrosis (“CF”), a life-threatening geneti...Show more
    Last updated: 30+ days ago • Promoted
    Director of Endocrinology

    Director of Endocrinology

    Signature Healthcare • Brockton, US
    Full-time
    Come join our team at Signature Healthcare! This is a great opportunity for a BC Endocrinologist that thrives on providing excellent patient care and has an interest in clinical leadership.Our team...Show more
    Last updated: 30+ days ago • Promoted
    Director, Global Marketing Campaigns

    Director, Global Marketing Campaigns

    Sitecore USA, Inc. • Boston, MA, US
    Full-time
    At Sitecore, our mission is to simplify how brands reach, engage, and serve people by delivering intelligent, personalized digital experiences that connect the world. We empower the world's most ico...Show more
    Last updated: 30+ days ago • Promoted
    Director, Commercial Manufacturing

    Director, Commercial Manufacturing

    Zevra Therapeutics, Inc. • Boston, MA, United States
    Full-time
    We are a rare disease therapeutics company leading with science to make life-changing therapeutics available to patients with significant unmet needs. We involve key thought leaders, physicians, pat...Show more
    Last updated: 30+ days ago • Promoted
    Director Business Development - Last Mile

    Director Business Development - Last Mile

    Ryder System, Inc. • Boston, MA, United States
    Full-time
    Job Seekers can review the Job Applicant Privacy Policy by clicking here (http : / / ryder.The Director Business Development DBD is responsible for leading the pursuit of new business and expansion / ren...Show more
    Last updated: 29 days ago • Promoted
    Clinical Director

    Clinical Director

    Spectrum Health Systems, Inc • Lawrence, MA, United States
    Full-time
    Essex County Sheriff's Department Pre-Release Center inLawrence, MA.Health, dental, vision insurance.Discounts on wide array of services / entertainment. The oversight of clinical and case management ...Show more
    Last updated: 30+ days ago • Promoted
    Senior Customer Manager, Americas

    Senior Customer Manager, Americas

    6149-DePuy Synthes Products Legal Entity • Raynham, Massachusetts, USA
    Full-time
    At Johnson & Johnsonwe believe health is everything.Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are ...Show more
    Last updated: 21 days ago • Promoted
    Director, Global Commercial Team, Rheumatology

    Director, Global Commercial Team, Rheumatology

    argenx SE • Boston, MA, United States
    Full-time
    VYVGART, our first-in-class neonatal Fc receptor blocker approved for the treatment of gMG, and with the potential to treat patients across dozens of severe autoimmune diseases.We are building a ne...Show more
    Last updated: 4 days ago • Promoted
    Director of Operations - HVAC

    Director of Operations - HVAC

    CyberCoders • Hanover, MA, United States
    Full-time
    One of New England's top mechanical contractors and best places to work is looking to add a Director of Operations for the HVAC division. This is a great opportunity for a HVAC pro to put their stam...Show more
    Last updated: 30+ days ago • Promoted
    VP Commercial Lending

    VP Commercial Lending

    MountainOne • Rockland, MA, United States
    Full-time +1
    All qualified applicants will receive consideration for employment without regard to race, color, sex (including pregnancy and related conditions, sexual orientation, or gender identity), national ...Show more
    Last updated: 30+ days ago • Promoted
    Global Commercial Director, T2D & CVRM Strategy

    Global Commercial Director, T2D & CVRM Strategy

    AstraZeneca • Boston, MA, United States
    Full-time
    A global biopharmaceutical company seeks a Global Commercial Director for T2D initiatives in Boston.The ideal candidate will have over 10 years of experience in pharmaceutical commercial strategy, ...Show more
    Last updated: 4 hours ago • Promoted • New!