Talent.com
Senior Director, US Payer Medical Affairs & Outcomes Strategy
Senior Director, US Payer Medical Affairs & Outcomes StrategyAlnylam Pharmaceuticals • Cambridge, MA, United States
Senior Director, US Payer Medical Affairs & Outcomes Strategy

Senior Director, US Payer Medical Affairs & Outcomes Strategy

Alnylam Pharmaceuticals • Cambridge, MA, United States
30+ days ago
Job type
  • Full-time
Job description

Overview

The Senior Director, US Payer Medical Affairs & Outcomes Strategy will report to the Vice President of US Medical Affairs, TTR and will have dual accountability across two core domains :

  • Medical Director Leadership (50%) - Lead the design and execution of the US Payer Ecosystem Medical Plan, including real-world evidence (RWE) strategy and collaborative pilots with payer organizations. Partner with internal and external stakeholders to generate meaningful insights that support patient access, value demonstration, and differentiation of Alnylam's portfolio.
  • Field Team Leadership (50%) - Oversee the US Payer Medical Outcomes Science Liaisons (MOSLs), ensuring strategic alignment and flawless execution of payer-focused initiatives. Provide coaching, mentoring, and performance management to optimize team impact across the managed care landscape.

This position is a US-Field based position.

Key Responsibilities

US Payer Medical Director Accountabilities (50%)

  • Lead the US Payer Ecosystem Medical Plan in alignment with brand, evidence generation, and access strategies.
  • Develop and implement a real-world payer evidence strategy that includes payer-driven research collaborations, pragmatic pilots, and data partnerships to address evidence needs for access and reimbursement.
  • Serve as the primary scientific and clinical point of contact for US payer stakeholders, including PBMs, MCOs, IDNs, and state Medicaid programs.
  • Collaborate with Health Economics & Outcomes Research (HEOR), Value & Access, and Policy teams to ensure payer evidence needs are incorporated into US and global evidence plans.
  • Shape and lead strategic payer-focused research collaborations , ensuring alignment with both scientific rigor and payer decision-making needs.
  • Act as a thought leader in payer-focused evidence generation , representing Alnylam in external forums and advancing partnerships with US healthcare systems.
  • US Payer MOSL Team Leadership (50%)

  • Lead and manage theUS Payer MOSL organization, ensuring execution of strategy with excellence and consistency across regions.
  • Translate payer evidence needs into actionableMOSL field engagement strategies, aligning account planning with corporate medical objectives.
  • Providecoaching, development, and performance oversightfor MOSLs, fostering a culture of accountability, collaboration, and innovation.
  • Partner closely with National Accounts, Market Access, and US Medical leadership to deliver an integrated field medical strategy across payer segments.
  • Ensure strict compliance with all applicable PhRMA Codes, FDA laws, regulations, and company policies.
  • Champion cross-functional collaboration to align payer field activities with corporate priorities and ensure seamless execution.
  • Qualifications

  • 10+ years of experience inMedical Affairs, HEOR, or payer-focused functions within biopharma / healthcare.
  • Required : Experienceeither at a US payer organization(e.g., MCO, PBM, Medicaid / Medicare, IDN)or within the pharmaceutical / biotech industry leading US payer medical and evidence strategy.
  • Advanced degree in life sciences (MD, DO, PharmD, PhD) strongly preferred.
  • Proven experience developing and executingpayer medical strategiesandreal-world evidence initiatives.
  • Deep understanding of theUS payer landscape, including policy, access drivers, and evidence requirements.
  • Demonstrated leadership experience managing field medical teams or payer-facing medical organizations.
  • Excellent scientific communication skills with ability to engage credibly with payer medical directors, pharmacy directors, and value committees.
  • Strong organizational and strategic planning skills, with a track record ofleading cross-functional initiatives.
  • Ability to travel up to 50%.
  • U.S. Pay Range

    $240,600.00 - $325,500.00

    The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

    Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

    Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website : https : / / www.alnylam.com / careers

    AboutAlnylam

    We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values : fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another.

    At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

    Create a job alert for this search

    Senior Director Medical • Cambridge, MA, United States

    Related jobs
    Senior Director / Director Clinical Development

    Senior Director / Director Clinical Development

    Biontech • Cambridge, MA, US
    Full-time
    Senior Director / Director Clinical Development.New Jersey, US; Cambridge, US; Gaithersburg, US | full time | Job ID : 9682. The (Senior) Director, Clinical Development will collaborate closely with th...Show more
    Last updated: 16 days ago • Promoted
    Director, Healthcare Solutions

    Director, Healthcare Solutions

    J&J Family of Companies • Danvers, MA, US
    Full-time
    Cardiovascular Director, Healthcare Solutions.Fueled by innovation at the intersection of biology and technology, we're developing the next generation of smarter, less invasive, more personalized t...Show more
    Last updated: 7 hours ago • Promoted • New!
    Medical Director - Radiation Oncology - Anywhere in US

    Medical Director - Radiation Oncology - Anywhere in US

    UnitedHealth Group • Boston, MA, United States
    Full-time
    Optum is a global organization that delivers care, aided by technology to help millions of people live healthier lives.The work you do with our team will directly improve health outcomes by connect...Show more
    Last updated: 30+ days ago • Promoted
    Director, Clinical Quality Assurance

    Director, Clinical Quality Assurance

    Eisai • Andover, MA, United States
    Full-time
    At Eisai, satisfying unmet medical needs and increasing the benefits healthcare provides to patients, their families, and caregivers is Eisai's human health care (hhc) mission.We're a growing pharm...Show more
    Last updated: 30+ days ago • Promoted
    Clinical Operations Director (Pain Management Center)

    Clinical Operations Director (Pain Management Center)

    Beth Israel Lahey Health • Boston, MA, US
    Full-time
    Leadership Opportunity At Beth Israel Deaconess Medical Center.When you join the growing BILH team, you're not just taking a job, you're making a difference in people's lives.Leads operational init...Show more
    Last updated: 30+ days ago • Promoted
    Director of Endocrinology

    Director of Endocrinology

    Signature Healthcare • Brockton, US
    Full-time
    Come join our team at Signature Healthcare! This is a great opportunity for a BC Endocrinologist that thrives on providing excellent patient care and has an interest in clinical leadership.Our team...Show more
    Last updated: 30+ days ago • Promoted
    OBGYN Director | Near Portland, OR | $100,000 Sign-On

    OBGYN Director | Near Portland, OR | $100,000 Sign-On

    Jackson Physician Search • Salem, US
    Full-time
    A large community hospital 45 minutes from Portland, OR is searching for a physician leader to oversee Women's Services.The typical schedule consists of 3 days in clinic, 1 OR day, and 1 dedicated ...Show more
    Last updated: 30+ days ago • Promoted
    Regional Director, Sites

    Regional Director, Sites

    Iterative Health • Cambridge, MA, US
    Full-time
    Iterative Health is a healthcare technology and services company powering the acceleration of clinical research to transform patient outcomes. The Iterative Health Site Network is a premier network ...Show more
    Last updated: 30+ days ago • Promoted
    Senior Director, Access Strategy Established Products

    Senior Director, Access Strategy Established Products

    Sanofi • Cambridge, MA, United States
    Full-time
    Senior Director, Access Strategy Established Products.Morristown, NJ or Cambridge, MA.The Sr Director, Access Strategy Established Products will lead a small team and be responsible for developing ...Show more
    Last updated: 30+ days ago • Promoted
    Medical Director Interventional Cardiology

    Medical Director Interventional Cardiology

    Tandym Health • Lawrence, MA, US
    Full-time
    A healthcare network in Massachusetts is currently seeking a licensed Interventional Cardiologist to join their facility in Essex County as their new Medical Director. Specialty : Interventional Card...Show more
    Last updated: 30+ days ago • Promoted
    Medical Director

    Medical Director

    Brooksby Village by Erickson Senior Living • Peabody, MA, US
    Full-time
    Brooksby Village by Erickson Senior Living.We are hiring a Medical Director to join our growing physician-lead geriatrics practice. Erickson Senior Living,® a national leader in senior living an...Show more
    Last updated: 30+ days ago • Promoted
    Clinical Director

    Clinical Director

    Spectrum Health Systems, Inc • Lawrence, MA, United States
    Full-time
    Essex County Sheriff's Department Pre-Release Center inLawrence, MA.Health, dental, vision insurance.Discounts on wide array of services / entertainment. The oversight of clinical and case management ...Show more
    Last updated: 30+ days ago • Promoted
    Physician Medical Director - Competitive Salary

    Physician Medical Director - Competitive Salary

    FCS, Inc. • Taunton, MA, US
    Full-time
    Psychiatrist need part-time for a.Medical Director role at a Community Mental Health Center in Southeastern Mass.Work in tandem with program director and 12-person multidisciplinary team serving me...Show more
    Last updated: 30+ days ago • Promoted
    Sr. Director, Payer Reimbursement & Pricing

    Sr. Director, Payer Reimbursement & Pricing

    Foundation Medicine, Inc. • Boston, MA, US
    Full-time
    About the Job The Senior Director Payer Reimbursement and Pricing position involves assessing existing portfolio and new products reimbursement dynamics and commercial and government payer requirem...Show more
    Last updated: 8 days ago • Promoted
    Pain Medical Affairs Director - Hybrid Strategy Leader

    Pain Medical Affairs Director - Hybrid Strategy Leader

    Ccrps • Boston, MA, United States
    Full-time
    A leading biotechnology company in Boston is seeking a Medical Director for Medical Affairs Strategy.This role involves providing medical leadership for the US Pain team and developing and executin...Show more
    Last updated: 4 hours ago • Promoted • New!
    Sr. Director, Clinical Programs, Global Rare Diseases

    Sr. Director, Clinical Programs, Global Rare Diseases

    Chiesi • Boston, MA, United States
    Full-time
    Based in Parma, Italy, Chiesi is an international research-focused biopharmaceutical group with 90 years' experience, operating in 31 countries. More than 8,000 employees across the group are united...Show more
    Last updated: 29 days ago • Promoted
    Regional Director of Outpatient Services

    Regional Director of Outpatient Services

    UHS • Boston, MA, United States
    Full-time
    Regional Director of Outpatient Services - Behavioral Health Division.The Regional Director is responsible for overseeing the development and management of outpatient service lines across an assign...Show more
    Last updated: 15 days ago • Promoted
    Senior Director, US Finance Lead

    Senior Director, US Finance Lead

    argenx SE • Boston, MA, United States
    Full-time
    Senior Director, US Finance Lead page is loaded## Senior Director, US Finance Leadlocations : Boston, MA, USAtime type : Full timeposted on : Posted Todayjob requisition id : REQ-3810 •Join us a...Show more
    Last updated: 30+ days ago • Promoted