PK/PD Modeling / Pharmacometrics LeadMercor • Tampa, Florida, US
PK / PD Modeling / Pharmacometrics Lead
Mercor • Tampa, Florida, US
21 hours ago
Job type
- Part-time
- Remote
Job descriptionWho we’re looking for Deep hands-on experience in PK, PD, exposure–response modeling , and ideally population PK or QSP . - Expert at model fitting, sensitivity analysis, and identifying non-plausible parameter spaces. - Can evaluate the validity of dose–exposure predictions and detect high-risk extrapolations. - Comfortable designing model evaluation rubrics that distinguish between acceptable vs. non-credible outputs. - Able to articulate how quantitative checks should complement narrative decision logic. Nice-to-have : Experience supporting translational or clinical pharmacology leads in dose justification. - Familiarity with integrating nonclinical PK / PD data (2-species GLP → human FIH extrapolation). ### Experience level ~8–12 years of quantitative pharmacology experience in pharma, CROs, or modeling consultancies . - Strong portfolio in population PK / PD exposure–response , and parameter estimation using NONMEM, Monolix, or equivalent tools. - Demonstrated ability to interpret model results for decision-making, not just fit data. - Can create fit-for-purpose models and critique model structures or assumptions under uncertainty. ### Expectations Design and refine micro-evaluations for PK / PD performance (curve fits, parameter checks, error taxonomies). - Encode quantitative sanity checks into model rubrics for automated evaluation. - Define failure conditions (e.g., unsafe extrapolation, poor coverage curves, invalid assumptions). Inputs we give : PK / PD datasets, tox summaries, and performance prompts (e.g., “fit exposure–response curves, interpret safety margins”). - Example model outputs from automated systems. Expected outputs : Quantitative Rubrics : clear thresholds for acceptable parameter fits, coverage curve quality, and model integrity checks. - Golden Fit Examples : representative “ideal” PK / PD model outputs and visualizations for calibration. - Error Taxonomy : structured list of typical modeling or fitting errors, with root-cause annotations. - Meta-Layer Commentary : short note per rubric capturing how expert modelers recognize implausible or unsafe fits beyond numeric error values. ### Engagement Model & Compensation Contract / part-time , remote, outcome-based deliverables.
This person complements the client’s “Translational / Clinical Pharmacology Decision-Maker” team by grounding dose selection and exposure–response analysis in
- quantitative structure and parameter plausibility
###
Create a job alert for this search
Modeling • Tampa, Florida, US
Related jobs
BayCare is looking for its newest EP Tech in Tampa, FL.The EP Tech serves as a member of the Cardiovascular and Interventional Services Team assisting in the performance of diagnostic and invasive ...Show more
Neurology – Independent Practice Track (MedCBO Supported).MedCBO is a Colorado-based healthcare business infrastructure company that empowers independent physician groups across the United States t...Show more
Location : Tampa, FL (Only Local & 5 Days onsite).Banking Domain Experience 3 Years and Onsite Experience 5 Years are mandatory.
Design, develop, and implement Pega applications using Pega PRPC 8.Col...Show more
Our innovative EHR and clinical solutions empower providers to deliver better care streamline operations and improve patient outcomes.
As part of our Juno Health Technical Services team youll work w...Show more
Cooperidge Consulting Firm is seeking a.Medical Technologist (Med Tech).This crucial laboratory role performs stat and routine clinical testing across multiple disciplines, including Blood Bank, Ch...Show more
Prosper Infusion is a leading provider in home Infusion therapy.We are looking for a AR Specialist to join our Revenue Cycle Management (RCM) team as we grow to be one of the top home infusion prov...Show more
Cytotech or Cytotechnologist Needed in Tampa, FL for Permanent and Full-Time Hire - CLICK AND APPLY NOW!.Medical Diagnostic Laboratories (MDL), a member of Genesis Biotechnology Group, specializes ...Show more
The Surgical Service Department at James A.Haley Veterans Hospital in Tampa, Florida, is actively recruiting a Board Certified or Board Eligible Urologist to join our growing team of dedicated prof...Show more
At Moffitt Cancer Center, we strive to be the leader in understanding the complexity of cancer and applying these insights to contribute to the prevention and cure of cancer.Our diverse team of ove...Show more
LocumJobsNetwork is working with Weatherby Healthcare to find a qualified Rheumatology MD in Panama City, Florida, 32405!.
If this opportunity sounds right for you, give us a call today to speak wit...Show more
LocumJobsOnline is working with Weatherby Healthcare to find a qualified Rheumatology MD in Panama City, Florida, 32405!.
If this opportunity sounds right for you, give us a call today to speak with...Show more A healthcare business company seeks a Nephrology specialist to develop innovative solutions that enhance patient care.You'll focus on establishing a physician group while leading initiatives for op...Show more 
Join our team at Core One! Our mission is to be at the forefront of devising analytical operational and technical solutions to our Nations most complex national security order to achieve our missi...Show more
Revitalize Lives Where It Matters : Join Our Acute Care Physical Therapy Team in Tampa, Florida.Imagine a day where your expertise helps a patient regain their footing after a surgery, regain a joyf...Show more
Endocrinology physician employment in Florida : Well respected multi specialty group in Tampa continues to experience growth and is now looking to add a BE / BC Endocrinologist.Guaranteed base salary...Show more
If you are a current Jazz employee please apply via the Internal Career site.Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and ...Show more LocumJobsNetwork is working with Rhino Medical to find a qualified Emergency Medicine MD in Panama City, Florida, 32405!.
Panama City, FL Emergency Medicine Physician Locum Tenens.Rhino Medical is l...Show more 
Specimen Processing Manager - Tampa, FL, Monday to Friday, 5 : 00 AM to 2 : 00 PM.Salary offers are based on a wide range of factors including relevant skills, training, experience, education, and, whe...Show more
EP Tech
BayCare Health System • Tampa, FL, United States
Full-time
Last updated: 17 days ago • Promoted
Neurology – Independent Practice Track (MedCBO Supported)
MedCBO, Inc • Tampa, FL, United States
Full-time
Last updated: 13 days ago • Promoted
Pega Developer || Tampa, FL (Only Local & 5 Days onsite)
Inficare • Tampa, FL, United States
Full-time
Last updated: 4 days ago • Promoted
Clinical Analyst I (JHTS)
Document Storage Systems • Tampa, Florida, USA
Full-time
Last updated: 19 days ago • Promoted
Med Tech
Cooperidge Consulting Firm • Tampa, FL, US
Full-time
Quick Apply
Last updated: 28 days ago
AR Specialist / Healthcare Billing / Pharmacy
Prosper Infusion • Tampa, FL, US
Full-time
Quick Apply
Last updated: 30+ days ago
Cytotech or Cytotechnologist Needed in Tampa, FL!
K.A. Recruiting • Tampa, FL, United States
Full-time
Last updated: 30+ days ago • Promoted
Urologist – VA Tampa Healthcare System
Department of Veteran Affairs • Tampa, FL, US
Full-time +1
Last updated: 30+ days ago • Promoted
Epic Clinical Application Analyst Pharmacist
Moffitt Cancer Center • Tampa, FL, United States
Full-time
Last updated: 9 days ago • Promoted
Locum Physician (MD / DO) - Rheumatology in Panama City, FL
LocumJobsNetwork • Tampa, US
Full-time
Last updated: 30+ days ago • Promoted
Locum Physician (MD / DO) - Rheumatology in Panama City, FL
LocumJobsOnline • Tampa, US
Full-time
Last updated: 30+ days ago • Promoted
Nephrologist - Independent Practice Leader (Hybrid / Remote)
MedCBO, Inc • Tampa, FL, United States
Remote
Full-time
Last updated: 13 days ago • Promoted
Modeling and Simulation SME
Core One • Tampa, Florida, USA
Full-time
Last updated: 2 days ago • Promoted
DPT - Acute Care / Outpatient Physical Therapist
MLee Healthcare Staffing and Recruiting, Inc • Tampa, FL, United States
Full-time
Last updated: 4 days ago • Promoted
Endocrinology
myMDCareers • Tampa, Florida, US
Full-time
Last updated: 30+ days ago • Promoted
Thought Leader Liaison Southeast Region (Remote)
Jazz Pharmaceuticals • Tampa, FL, United States
Remote
Full-time
Last updated: 19 days ago • Promoted
Locum Physician (MD / DO) - Emergency Medicine in Panama City, FL
LocumJobsNetwork • Tampa, US
Full-time
Last updated: 30+ days ago • Promoted
Specimen Processing Manager
Quest Diagnostics • Tampa, FL, United States
Full-time +1
Last updated: 4 days ago • Promoted