Associate Scientist

Job Title : Associate Scientist

Duration : 12 months on W2 Contract (Possible Extension based on performance)

Location : Seattle, WA 98109

Onsite / Hybrid : Onsite

Work Schedule- M-F; Standard Business Hours

Job Description :

The primary focus of this Associate Scientist will be to support process development, production, and characterization of early and late-stage viral vectors (lentiviral vectors and / or adeno-associated viruses). This position will be providing technical subject matter expertise with internal and / or external development and manufacturing collaborators for activities including tech transfer, process characterization, and pre-clinical or clinical process lifecycle management.

Responsibilities :

Design, execute, and troubleshoot upstream development experiments supporting next-generation LVV production

Identify, onboard, and develop Client upstream technologies in collaboration with internal and external partners

Provide experimental design and executional support to team members

Support cross-functional development efforts e.g. downstream process development, high-throughput process development

Generate representative crude harvest material to support downstream development activities

Work independently and within teams to design, execute, and analyze experiments

Maintain accurate and detailed laboratory notebook and documentation

Summarize and present data in group meetings and contribute to group discussions and team strategy

Author technical reports and study memos

Basic Qualifications :

B.S. with 2+ years of experience or M.S. with 0-2 years of hands-on upstream experience

Experience with suspension culture of mammalian cells in shake flasks and small stirred tank bioreactors

Experience with transient transfection operations to produce viral vectors (e.g. adeno-, retro-, lenti)

Hands-on process development experience

Independently motivated with ability to mulit-task, problem-solve, and coordinate activities within a team

Ability to design experiments with design of experiment (DOE) approaches, perform experiments, and interpret the results using statistical software (ex. JMP)

Preferred Qualifications :

Degree in biological or chemical engineering, biochemistry, or bio-related field

Experience in the development of viral vectors (e.g. adeno-, retro-, lenti-), including successful transfer for GMP manufacturing

Experience with single-use technologies