PK/PD Modeling / Pharmacometrics LeadMercor • Maplewood, Minnesota, US
PK / PD Modeling / Pharmacometrics Lead
Mercor • Maplewood, Minnesota, US
13 hours ago
Job type
- Part-time
- Remote
Job descriptionWho we’re looking for Deep hands-on experience in PK, PD, exposure–response modeling , and ideally population PK or QSP . - Expert at model fitting, sensitivity analysis, and identifying non-plausible parameter spaces. - Can evaluate the validity of dose–exposure predictions and detect high-risk extrapolations. - Comfortable designing model evaluation rubrics that distinguish between acceptable vs. non-credible outputs. - Able to articulate how quantitative checks should complement narrative decision logic. Nice-to-have : Experience supporting translational or clinical pharmacology leads in dose justification. - Familiarity with integrating nonclinical PK / PD data (2-species GLP → human FIH extrapolation). ### Experience level ~8–12 years of quantitative pharmacology experience in pharma, CROs, or modeling consultancies . - Strong portfolio in population PK / PD exposure–response , and parameter estimation using NONMEM, Monolix, or equivalent tools. - Demonstrated ability to interpret model results for decision-making, not just fit data. - Can create fit-for-purpose models and critique model structures or assumptions under uncertainty. ### Expectations Design and refine micro-evaluations for PK / PD performance (curve fits, parameter checks, error taxonomies). - Encode quantitative sanity checks into model rubrics for automated evaluation. - Define failure conditions (e.g., unsafe extrapolation, poor coverage curves, invalid assumptions). Inputs we give : PK / PD datasets, tox summaries, and performance prompts (e.g., “fit exposure–response curves, interpret safety margins”). - Example model outputs from automated systems. Expected outputs : Quantitative Rubrics : clear thresholds for acceptable parameter fits, coverage curve quality, and model integrity checks. - Golden Fit Examples : representative “ideal” PK / PD model outputs and visualizations for calibration. - Error Taxonomy : structured list of typical modeling or fitting errors, with root-cause annotations. - Meta-Layer Commentary : short note per rubric capturing how expert modelers recognize implausible or unsafe fits beyond numeric error values. ### Engagement Model & Compensation Contract / part-time , remote, outcome-based deliverables.
This person complements the client’s “Translational / Clinical Pharmacology Decision-Maker” team by grounding dose selection and exposure–response analysis in
- quantitative structure and parameter plausibility
###
Create a job alert for this search
Modeling • Maplewood, Minnesota, US
Related jobs
As a Clinical Manager with Fresenius Medical Care, you will ensure that quality patient care is delivered while maintaining clinical operations.
As the facility leader, you will be part of a close-k...Show more
PRIDE Health is seeking a travel CT Technologist for a travel job in Cannon Falls, Minnesota.Job Description & Requirements.
Job Summary : -Produces high quality images for interpretation by phys...Show more This person complements the client’s “Translational / Clinical Pharmacology Decision-Maker” team by grounding dose selection and exposure–response analysis in • •quantitative structure and parameter...Show more 
LocumJobsOnline is working with CompHealth to find a qualified Urology MD in Madelia, Minnesota, 56062!.CompHealth exists to make the locums process easier.
Not only will we search for jobs that fit...Show more
Travel Radiology : MRI Tech Rochester, MN.Location : Rochester, MN.Shift Details : 8H Days (12 : 00 AM-12 : 00 PM).Length : 52 WEEKS 52 weeks.
Apply for specific facility details.Show more
AlliedTravelNetwork is working with Triage Staffing LLC to find a qualified CT Tech in Cannon Falls, Minnesota, 55009!.Travel Radiology : CT Tech Cannon Falls, MN.
Location : Cannon Falls, MN....Show more
Fusion Medical Staffing is seeking an experienced CT Tech for an exciting Travel Allied job in Cannon Falls, MN.Shift : Inquire Start Date : 01 / 05 / 2026 Duration : 13 weeks Pay : $2757 / Week.Facility i...Show more
Join a premier, physician-owned dermatology practice with 17 MDs practicing at the highest level of their training, supported by a highly skilled team of medical assistants, scribes, and administra...Show more
Ready for a career upgrade? Join Marten Transport! As a stable, financially healthy carrier – and a 2025 TCA Elite Fleet honoree – we offer the best of both worlds : high miles in your region and th...Show more
Home Daily CDL-B - Local Hazmat Delivery Driver.Only Candidates with 2 Years CDL Experience and Hazmat Will Be Considered • •.
Typically 45-50 hours per week.Home every day, morning start time, usuall...Show more
AlliedTravelCareers is working with Fusion Medical Staffing to find a qualified CT Tech in Cannon Falls, Minnesota, 55009!.
Facility in Cannon Falls, Minnesota.Fusion Medical Staffing is seeking a s...Show more
Join a growing practice serving two communities (Grand Island and Hastings).Morrision Cancer Center comprehensive Service (Medical and Radiation Oncology).
Build patient relationships that last a li...Show more
Northern NJ Oral Surgery Office seeking for a one day a week Oral Surgery to join our growing team.This existing practice is in a brand-new facility with all new equipment and technology.Large emph...Show more
As a CT technologist, you will use computerized tomography to take medical images of patients for diagnostic purposes.Working in a hospital, outpatient center, private practice, imaging center or o...Show more
Physical therapists work with patients to improve their movement and manage their pain.PTs use a variety of techniques to help their patients, including hands-on therapy, strengthening and stretchi...Show more
FlexCare is seeking an experienced CT Tech for an exciting Travel Allied job in Cannon Falls, MN.Shift : 5x8 hr flex Start Date : 12 / 29 / 2025 Duration : 13 weeks Pay : $3100 / Week.Level IV Trauma, Teac...Show more
LocumJobsNetwork is working with CompHealth to find a qualified Urology MD in Madelia, Minnesota, 56062!.CompHealth exists to make the locums process easier.
Not only will we search for jobs that fi...Show more
Job Description & Requirements.Physical Therapist - Outpatient - (PT) .StartDate : 1 / 5 / 2026 Available Shifts : 8 D Pay Rate : $2162.
PT- outpatient needed asap Critical Access Hospital in remote ...Show more
Dialysis Clinical Manager Registered Nurse - RN
Fresenius Medical Care • Hastings, MN, US
Full-time
Last updated: 30+ days ago • Promoted
Travel CT Radiologic Technologist
PRIDE Health • Cannon Falls, MN, US
Full-time
Last updated: 14 hours ago • Promoted • New!
PK / PD Modeling / Pharmacometrics Lead
Mercor • Woodbury, Minnesota, US
Remote
Part-time
Last updated: 13 hours ago • Promoted • New!
Locum Physician (MD / DO) - Urology in Madelia, MN
LocumJobsOnline • Saint Paul, US
Full-time +1
Last updated: 30+ days ago • Promoted
Travel MRI Tech - $3,123 per week in Rochester, MN
Triage Staffing LLC • Saint Paul, Minnesota, US
Full-time
Last updated: 7 days ago • Promoted
Travel CT Tech - $3,073 per week in Cannon Falls, MN
AlliedTravelNetwork • Cannon Falls, MN, US
Full-time
Last updated: 18 hours ago • Promoted • New!
Travel CT Tech - $2757 / Week
Fusion Medical Staffing • Cannon Falls, MN, US
Full-time
Last updated: 1 day ago • Promoted
Board Certified / Board Eligible Dermatologist
Tareen Dermatology • Saint Paul, US
Full-time
Last updated: 30+ days ago • Promoted
CDL-A Refrigerated Truck Driver in Forest Lake, MN
AllTruckJobs • Forest Lake, MN, US
Full-time
Last updated: 30+ days ago • Promoted
CDL B Local Hazmat Truck Driver
Moran Transportation • Forest Lake, MN
Full-time
Last updated: 30+ days ago • Promoted
Travel CT Tech - $2,398 to $2,757 per week in Cannon Falls, MN
AlliedTravelCareers • Cannon Falls, MN, US
Full-time
Last updated: 16 hours ago • Promoted • New!
Medical Oncologist – Change the World One Patient at a time
Mary Lanning Healthcare • Hastings, US
Full-time
Last updated: 30+ days ago • Promoted
Hungry and Competent Oral Surgeon!!!!
Dickerson Dental Group • Randolph, US
Full-time
Last updated: 13 days ago • Promoted
Travel CT Tech - $2,900 per week in Cannon Falls, MN
Cross Country Allied • Cannon Falls, MN, US
Full-time
Last updated: 18 hours ago • Promoted • New!
Travel Physical Therapist (PT) - $2,514 per week in Belview, MN
Care Career • Saint Paul, Minnesota, US
Full-time
Last updated: 20 days ago • Promoted
Travel CT Tech - $3100 / Week
FlexCare • Cannon Falls, MN, US
Full-time
Last updated: 1 day ago • Promoted
Locum Physician (MD / DO) - Urology in Madelia, MN
LocumJobsNetwork • Saint Paul, US
Full-time +1
Last updated: 30+ days ago • Promoted
Travel Physical Therapist (PT) - $2,163 to $2,370 per week in Grand Marais, MN
AMN Healthcare Allied • Saint Paul, Minnesota, US
Full-time
Last updated: 7 days ago • Promoted