PK/PD Modeling / Pharmacometrics LeadMercor • Lacey, Washington, US
No longer accepting applications
PK / PD Modeling / Pharmacometrics Lead
Mercor • Lacey, Washington, US
1 day ago
Job type
- Part-time
- Remote
Job descriptionWho we’re looking for Deep hands-on experience in PK, PD, exposure–response modeling , and ideally population PK or QSP . - Expert at model fitting, sensitivity analysis, and identifying non-plausible parameter spaces. - Can evaluate the validity of dose–exposure predictions and detect high-risk extrapolations. - Comfortable designing model evaluation rubrics that distinguish between acceptable vs. non-credible outputs. - Able to articulate how quantitative checks should complement narrative decision logic. Nice-to-have : Experience supporting translational or clinical pharmacology leads in dose justification. - Familiarity with integrating nonclinical PK / PD data (2-species GLP → human FIH extrapolation). ### Experience level ~8–12 years of quantitative pharmacology experience in pharma, CROs, or modeling consultancies . - Strong portfolio in population PK / PD exposure–response , and parameter estimation using NONMEM, Monolix, or equivalent tools. - Demonstrated ability to interpret model results for decision-making, not just fit data. - Can create fit-for-purpose models and critique model structures or assumptions under uncertainty. ### Expectations Design and refine micro-evaluations for PK / PD performance (curve fits, parameter checks, error taxonomies). - Encode quantitative sanity checks into model rubrics for automated evaluation. - Define failure conditions (e.g., unsafe extrapolation, poor coverage curves, invalid assumptions). Inputs we give : PK / PD datasets, tox summaries, and performance prompts (e.g., “fit exposure–response curves, interpret safety margins”). - Example model outputs from automated systems. Expected outputs : Quantitative Rubrics : clear thresholds for acceptable parameter fits, coverage curve quality, and model integrity checks. - Golden Fit Examples : representative “ideal” PK / PD model outputs and visualizations for calibration. - Error Taxonomy : structured list of typical modeling or fitting errors, with root-cause annotations. - Meta-Layer Commentary : short note per rubric capturing how expert modelers recognize implausible or unsafe fits beyond numeric error values. ### Engagement Model & Compensation Contract / part-time , remote, outcome-based deliverables.
This person complements the client’s “Translational / Clinical Pharmacology Decision-Maker” team by grounding dose selection and exposure–response analysis in
- quantitative structure and parameter plausibility
###
Create a job alert for this search
Modeling • Lacey, Washington, US
Related jobs
Now Hiring : Physical Therapist – Join Elevate Sports and Spine in Lacey, WA!.Are you ready to love where you work and make an impact in your community? Elevate Sports and Spine, a locally owned ort...Show more
Cynet Health is seeking an experienced CT Tech for an exciting Travel Allied job in Gig Harbor, WA.Shift : 3x12 hr PMs Start Date : 12 / 22 / 2025 Duration : 13 weeks Pay : $2693.Ranked #5 Best Travel Nurs...Show more
At Powerback, we're on a mission to improve lives.As the leader in physical, occupational, speech, and respiratory therapies, we help older adults stay active and thrive while providing essential t...Show more
Premier Medical Staffing Services, LLC is seeking an experienced CT Tech for an exciting Travel Allied job in Gig Harbor, WA.
Shift : 3x12 hr nights Start Date : 12 / 08 / 2025 Duration : 13 weeks Pay : $25...Show more)
WHEN YOU WORK FOR US, WE WORK FOR YOU.With Titan Medical, you gain access to thousands of travel nursing and allied health jobs across the country.
You also get unmatched service.From the moment you...Show more
Sea Mar Community Health Centers was founded in 1978 with a single clinic in the South Park neighborhood of Seattle.Today, Sea Mar is Washington’s largest provider of community-based, comprehensive...Show more
Job Summary and Responsibilities.Virginia Mason Franciscan Health is actively seeking a passionate and dedicated full-time Primary Care Physician to join an established and thriving practice in the...Show more
Estimated payments include wages and expense reimbursement, are based on information available to Fusion at time of posting, and could vary depending on factors related to the facility or applicant...Show more
New Journeys Individual Resiliency Training (IRT) Clinician.Clarvida’s success is built on the strength of our people : individuals who bring the right skills and a deep commitment to our mission of...Show more
Proliance Surgeons is one of the largest surgical practices in the country, with over 450 providers including over 200 board-certified physicians providing treatment at more than 100 care centers i...Show more
An independently-owned, nationally-recognized and amazingly awesome staffing firm ready to work for you! A work ethic forged in the Midwest, we are here to stand by your side and help you find your...Show more Job Summary and Responsibilities.Virginia Mason Franciscan Health’s Center for Neurosciences and Spine is seeking an experienced Physician Assistant for a full time spine opportunity located ...Show more 
Family Medicine physician employment in Washington : .Providence Medical Group is seeking a full time Family Medicine physician to join the growing team of providers at the expanding Hawks Prairie F...Show more
New Graduates and Experienced Clinicians are welcome to apply!.Are you a Physical Therapist looking to thrive in a supportive, balanced environment? Join ATI, a leader in Physical Therapy, where yo...Show more
Medical Solutions is seeking an experienced Physical Therapy Assistant for an exciting Travel Allied job in Lacey, WA.Shift : 5x8 hr days Start Date : 12 / 15 / 2025 Duration : 13 weeks.A facility in Lace...Show more
Medpro Healthcare Staffing is seeking an experienced CT Tech for an exciting Travel Allied job in Gig Harbor, WA.Shift : 3x12 hr flex Start Date : 12 / 15 / 2025 Duration : 13 weeks Pay : $2692 / Week.Join...Show more
Are you a Physical Therapist looking to thrive in a supportive, balanced environment? Join ATI, a leader in Physical Therapy, where you'll be part of a team redefining MSK care.With a mission to de...Show more
NW Sports, a brand partner of Upstream Rehabilitation, is looking for a Physical Therapist Clinic Director to join our team in Lacey, WA.
SALARY RANGE : $85,000 - $105,000.NW Sports is committed to y...Show more
Physical Therapist
Elevate Sports and Spine Physical Therapy • Lacey, WA, United States
Full-time
Last updated: 30+ days ago • Promoted
Travel CT Tech - $2693.76 / Week
Cynet Health • Gig Harbor, WA, US
Full-time
Last updated: 10 days ago • Promoted
Physical Therapist
Powerback Rehabilitation • Lacey, WA, United States
Full-time +1
Last updated: 30+ days ago • Promoted
Travel CT Tech - $2528.84 / Week
Premier Medical Staffing Services, LLC • Gig Harbor, WA, US
Full-time
Last updated: 23 days ago • Promoted
Travel - MRI Tech
Titan Medical (Nebraska) • Gig Harbor, WA, United States
Full-time
Last updated: 3 hours ago • Promoted • New!
Pediatric Provider (MD, DO)
SeaMar Community Health Centers • Lakewood, WA, United States
Full-time
Last updated: 30+ days ago • Promoted
Physician Fam Med or IM - Lakewood
CommonSpirit Health • Lakewood, US
Full-time
Last updated: 30+ days ago • Promoted
Physical Therapist - PT
Fusion Medical Staffing • Lacey, WA, United States
Full-time
Last updated: 4 days ago • Promoted
(IRT) Clinician - New Journeys
Clarvida • Lakewood, WA, US
Full-time
Last updated: 30+ days ago
Sterile Processing Tech (SPD)
Proliance Surgeons • Lakewood, WA, United States
Full-time
Last updated: 2 days ago • Promoted
Travel Physical Therapist (PT) - $2,295 per week in Lakewood, WA
OneStaff Medical • Lakewood, WA, United States
Full-time
Last updated: 4 days ago • Promoted
Advanced Practice Provider Orthopedic Spine Surgery
CommonSpirit Health • Gig Harbor, US
Full-time
Last updated: 23 days ago • Promoted
Family Medicine
Provider Solutions & Development • Lacey, Washington, US
Full-time
Last updated: 1 day ago • Promoted
Physical Therapist - Sign On Bonus up to $10K
ATI Physical Therapy Company • Gig Harbor, WA, United States
Full-time
Last updated: 30+ days ago • Promoted
Travel Physical Therapy Assistant
Medical Solutions • Lacey, WA, US
Full-time
Last updated: 14 days ago • Promoted
Travel CT Tech - $2692 / Week
Medpro Healthcare Staffing • Gig Harbor, WA, US
Full-time
Last updated: 26 days ago • Promoted
Physical Therapist
ATI Physical Therapy • Yelm, WA, United States
Full-time
Last updated: 30+ days ago • Promoted
Physical Therapist - Clinic Director
Upstream Rehabilitation, Inc. • Lacey, WA, United States
Full-time +1
Last updated: 30+ days ago • Promoted