PK/PD Modeling / Pharmacometrics LeadMercor • Huber Heights, Ohio, US
PK / PD Modeling / Pharmacometrics Lead
Mercor • Huber Heights, Ohio, US
19 hours ago
Job type
- Part-time
- Remote
Job descriptionWho we’re looking for Deep hands-on experience in PK, PD, exposure–response modeling , and ideally population PK or QSP . - Expert at model fitting, sensitivity analysis, and identifying non-plausible parameter spaces. - Can evaluate the validity of dose–exposure predictions and detect high-risk extrapolations. - Comfortable designing model evaluation rubrics that distinguish between acceptable vs. non-credible outputs. - Able to articulate how quantitative checks should complement narrative decision logic. Nice-to-have : Experience supporting translational or clinical pharmacology leads in dose justification. - Familiarity with integrating nonclinical PK / PD data (2-species GLP → human FIH extrapolation). ### Experience level ~8–12 years of quantitative pharmacology experience in pharma, CROs, or modeling consultancies . - Strong portfolio in population PK / PD exposure–response , and parameter estimation using NONMEM, Monolix, or equivalent tools. - Demonstrated ability to interpret model results for decision-making, not just fit data. - Can create fit-for-purpose models and critique model structures or assumptions under uncertainty. ### Expectations Design and refine micro-evaluations for PK / PD performance (curve fits, parameter checks, error taxonomies). - Encode quantitative sanity checks into model rubrics for automated evaluation. - Define failure conditions (e.g., unsafe extrapolation, poor coverage curves, invalid assumptions). Inputs we give : PK / PD datasets, tox summaries, and performance prompts (e.g., “fit exposure–response curves, interpret safety margins”). - Example model outputs from automated systems. Expected outputs : Quantitative Rubrics : clear thresholds for acceptable parameter fits, coverage curve quality, and model integrity checks. - Golden Fit Examples : representative “ideal” PK / PD model outputs and visualizations for calibration. - Error Taxonomy : structured list of typical modeling or fitting errors, with root-cause annotations. - Meta-Layer Commentary : short note per rubric capturing how expert modelers recognize implausible or unsafe fits beyond numeric error values. ### Engagement Model & Compensation Contract / part-time , remote, outcome-based deliverables.
This person complements the client’s “Translational / Clinical Pharmacology Decision-Maker” team by grounding dose selection and exposure–response analysis in
- quantitative structure and parameter plausibility
###
Create a job alert for this search
Modeling • Huber Heights, Ohio, US
Related jobs
LocumJobsOnline is working with Weatherby Healthcare to find a qualified Emergency Medicine MD in Sidney, Ohio, 45365!.Weatherby can help you build a custom career plan, with multiple positions ava...Show more
Centra Healthcare Allied is seeking a travel Physical Therapist for a travel job in Beavercreek, Ohio.Job Description & Requirements.
A great Outpatient Clinic is looking for an experienced or n...Show more
Core Medical Group is seeking a travel Physical Therapist for a travel job in Beavercreek, Ohio.Job Description & Requirements.
Client in OH seeking Physical Therapist : Outpatient / Clinic.We are ...Show more
Position Overview : This PT Float Position offers the option of a 4-day work week.Athletico’s Greater Purpose is to empower people, inspire hope and transform lives.
We accomplish this by providing e...Show more
Bestica is seeking a travel nurse RN Med Surg for a travel nursing job in Sidney, Ohio.Job Description & Requirements.Years of experience required .
Years of experience required \n\nACLS BL...Show more
We are looking for a finance professional to join our team to train AI models.You will measure the progress of these AI chatbots, evaluate their logic, and solve problems to improve the quality of ...Show more
The Leonardo DRS Airborne and Intelligence Systems business is a global leader and strategic partner committed to delivering world-class, full life-cycle defense and intelligence products that prot...Show more
Ethos Medical Staffing is seeking a local contract nurse RN Med Surg for a local contract nursing job in Sidney, Ohio.Job Description & Requirements.
Ethos Medical Staffing Job ID #35042475.Ethos Me...Show more
Junxion Med Staffing is seeking a travel nurse RN Med Surg for a travel nursing job in Sidney, Ohio.Job Description & Requirements.
Junxion Med Staffing is looking for a Med surg RN to take an a...Show more
Overview Credence is one of the largest privately held technology services companies in the country, repeatedly recognized as a top place to work and ranked on the Inc.
Fastest Growing Private Compa...Show more The Leonardo DRS Airborne and Intelligence Systems business is a global leader and strategic partner committed to delivering world-class, full life-cycle defense and intelligence products that prot...Show more 
AlliedTravelCareers is working with TRS Healthcare to find a qualified CT Tech in Sidney, Ohio, 45365!.TRS Healthcare is seeking an experienced Radiology - CT Scan CT Tech for a travel assignment i...Show more We are looking for a finance professional to join our team to train AI models.You will measure the progress of these AI chatbots, evaluate their logic, and solve problems to improve the quality of ...Show more 
HonorVet Technologies is seeking a travel nurse RN Med Surg for a travel nursing job in Sidney, Ohio.Job Description & Requirements.
HonorVet Technologies : Pioneering Purpose, Empowering Heroes.Foun...Show more
LocumJobsNetwork is working with Weatherby Healthcare to find a qualified Emergency Medicine MD in Sidney, Ohio, 45365!.Weatherby can help you build a custom career plan, with multiple positions av...Show more AlliedTravelCareers is working with Aya Healthcare to find a qualified CT Tech in Sidney, Ohio, 45365!.Aya Healthcare has an immediate opening for the following position : CT Tech in Sidney, OH.We’l...Show more 
Malone Healthcare - Nursing is seeking a travel CT Technologist for a travel job in Sidney, Ohio.Job Description & Requirements.
Multi-Modality CT / X-Ray Technologist Shift : Mid 3x12 | 1 : 00 PM – 1 : 0...Show more The client is seeking an external expert who brings a • •decision-maker’s mindset • • — someone who has personally driven translational pharmacology choices under governance and uncertainty.Who we’re ...Show more
Locum Physician (MD / DO) - Emergency Medicine in Sidney, OH
LocumJobsOnline • Sidney, OH, US
Full-time
Last updated: 14 days ago • Promoted
Travel Physical Therapist
Centra Healthcare Allied • Beavercreek, OH, US
Full-time
Last updated: 20 hours ago • Promoted • New!
Travel Outpatient Physical Therapist
Core Medical Group • Beavercreek, OH, US
Permanent +1
Last updated: 30+ days ago • Promoted
Physical Therapist Float
Athletico Physical Therapy • Fairborn, OH, United States
Full-time
Last updated: 13 hours ago • Promoted • New!
Travel Nurse RN - Med Surg
Bestica • Sidney, OH, US
Full-time
Last updated: 13 days ago • Promoted
Remote M&A Associate - AI Trainer ($50-$60 / hour)
Data Annotation • Huber Heights, Ohio
Remote
Full-time +1
Last updated: 22 days ago • Promoted
Senior Principal Systems Engineer (RF / Signal Processing)
Leonardo DRS • Beavercreek, OH, United States
Full-time
Last updated: 30+ days ago • Promoted
Local Contract Nurse RN - Med Surg - $61 per hour
Ethos Medical Staffing • Sidney, OH, United States
Full-time
Last updated: 2 days ago • Promoted
Travel Nurse RN - Med Surg
Junxion Med Staffing • Sidney, OH, US
Permanent
Last updated: 13 days ago • Promoted
Senior AI Technical Lead(s)
Credence • Fairborn, Ohio, US
Full-time
Last updated: 8 days ago • Promoted
Configuration and Data Manager
Leonardo DRS • Beavercreek, OH, United States
Full-time
Last updated: 30+ days ago • Promoted
Travel CT Tech - $2,586 per week in Sidney, OH
AlliedTravelCareers • Sidney, OH, US
Full-time
Last updated: 13 days ago • Promoted
Remote FinTech Product Analyst - AI Trainer ($50-$60 / hour)
Data Annotation • Huber Heights, Ohio
Remote
Full-time +1
Last updated: 30+ days ago • Promoted
Travel Nurse RN - Med Surg - $2,478 per week
HonorVet Technologies • Sidney, OH, United States
Full-time
Last updated: 1 day ago • Promoted
Locum Physician (MD / DO) - Emergency Medicine in Sidney, OH
LocumJobsNetwork • Sidney, OH, US
Full-time
Last updated: 14 days ago • Promoted
Travel CT Tech - $2,382 to $2,575 per week in Sidney, OH
AlliedTravelCareers • Sidney, OH, US
Full-time +1
Last updated: 23 days ago • Promoted
Travel CT Technologist - $2,434 per week
Malone Healthcare - Nursing • Sidney, OH, United States
Full-time
Last updated: 13 days ago • Promoted
PK / PD Module expert : Translational / Clinical Pharmacology Decision-Maker
Mercor • Huber Heights, Ohio, US
Remote
Full-time
Last updated: 19 hours ago • Promoted • New!