Global Head of Research and Biomarkers- Vaccines

Global Head of Research and Biomarkers- Vaccines

Join the team protecting half a billion lives every year with next-gen science, mRNA innovation, and AI-driven breakthroughs. In Vaccines, you'll help advance prevention on a global scale - and shape the future of immunization. Sanofi is a global biopharmaceutical company focused on human health transforming scientific innovation in healthcare solutions. At Sanofi, we innovate in immunology, rare diseases & prevention. Sanofi Pasteur has been a leader in the vaccine industry for over 100 years. We are building a world in which no one suffers or dies from a vaccine preventable disease. We produce more than 1 billion doses of high-quality vaccines each year and save over 3 million lives worldwide. Sanofi Pasteur is embracing the digital revolution. Today we incorporate big data, machine learning and advanced analytics into R&D, evidence generation, commercial operation and manufacturing. mRNA technology stands at the forefront of these scientific breakthroughs. In an ever-evolving healthcare landscape, we recognize mRNA's transformative potential to revolutionize how we prevent and treat diseases, making innovative solutions accessible to more people, faster than ever before. That's why we've established our mRNA Center of Excellence. With an annual investment of 200m and a dedicated team of 500+ experts, we built an integrated end-to-end mRNA platform that brings together R&D, digital capabilities, and CMC expertise under one roof. Bring your ambition and optimism and join us on our journey to discover and deliver transformative medicine to patients through the advancement of our cutting-edge mRNA technology!

In this role, the CTO, Global Head of Research & Biomarkers will be overseeing the overall end to end COE Research group covering pDNA, mRNA & Delivery (including Lipids discovery, associated synthesis) research teams and capabilities supporting Sanofi ambition in the field of therapeutic and prophylactic approaches serving unmet medical needs. Additionally, the CTO, Global Head of Research & Biomarkers will oversee a best-in-class mRNA Biomarker platform team based in France and Orlando, with the aim to :

• Maximize efficacy and safety of LNP-mRNA through deep molecular and cellular immune profiling
• Deciphering the impact of the LNPs components on immune innate response as well as overall humoral and cellular immunity
• Gain confidence in mRNA-based technology performance prediction

Overall, as such the Research and Biomarker Team will drive platform evolution and optimization through innovation in mRNA / LNP Design in prophylactic & therapeutic areas and will collaborate closely across the R&D team (Ag Design, Immunology Group, Clinical Development) and project teams to support development candidates.

As executive leader of the organization, the CTO, Global Head of Research & Biomarker is providing the best environment and support to project teams and scientists, enhance excellence in Science & Innovation in collaboration with key internal and external partners

Main Responsibilities

Lead, engage, drive and develop a team whose mission is to conduct research on mRNA, LNP and formulation (Delivery) design for various applications and specific routes of administration, including :

Lead, engage, drive, and develop the biomarker platform, including :

People

Is responsible for the selection, attraction, and retention of talents within mRNA CoE

Science and Innovation

Provide best environment and support to project teams and scientists

Culture & Vx R&D Voice

Act as the spokesperson / host for Vx R&D at site events, visitor welcomes and site visits. Act as a liaison to transfer information between Vx R&D and other functions. Vx R&D representative at the National Hub Leadership Team. Be the voice of the site for Vx R&D externally, interactions with local communities as appropriate and in collaboration with External Engagement teams Contribute to Vx R&D communication strategy at local level Lead initiatives to promote culture change, work performance, innovation & well-being

About You

Required Skills :

Why Choose Us?

Bring the miracles of science to life alongside a supportive, future-focused team. Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.