PK/PD Module expert: Translational / Clinical Pharmacology Decision-MakerMercor • Urbana, Illinois, US
PK / PD Module expert : Translational / Clinical Pharmacology Decision-Maker
Mercor • Urbana, Illinois, US
22 hours ago
Job type
- Full-time
- Remote
Job descriptionWho we’re looking for Has owned FIH starting dose, SAD / MAD design, and Phase 2 dose selection for multiple assets. - Participated in governance or review boards, defending dose / exposure rationale in front of senior leadership or regulators. - Demonstrates ability to balance nonclinical → clinical translation : tox, PK, PD, potency, and MoA. - Can articulate the real decision calculus behind dose selection (safety, pharmacology, speed-to-proof). - Capable of turning narrative judgment into explicit decision rules and rubrics for AI training and evaluation. ### Experience level ~10+ years in major biopharma or biotech (e.g., Lilly, Roche, AbbVie, Amgen, Novartis, GSK, Regeneron, Vertex, Incyte, Gilead) or in specialized translational pharmacology consulting. - Has personally led FIH dose and / or SAD / MAD escalation for ≥2–3 assets. - Proven governance experience : IND sign-off, dose justification memos, exposure–response presentations. - CV or track record includes statements like _“led clinical pharmacology strategy and FIH dose selection”_ or _“accountable for exposure–response in Phase 1 / 2.”_ - Avoid pure modeling profiles; the ideal expert has decision accountability , not just analytical skill. ### Expectations Write “golden” FIH dose rationales and escalation strategies for representative programs. - Encode the decision heuristics and trade-offs used by senior translational leaders into structured guidance and rubrics. - Surface unwritten decision rules — when and why experienced teams override model-based recommendations. Inputs given : Representative drug programs or data packets (GLP tox summaries, PK / PD tables, potency & MoA context). - Target prompts for translational decision-making (e.g., _“Recommend FIH dose and escalation strategy given these data”_). Expected outputs : Golden Decision Memos : exemplar dose justification memos that reflect the level of reasoning and format expected from top-tier translational pharmacologists. - Decision Rubrics : scoring guides capturing acceptable vs. unsafe dose rationales, missed edge cases, or failure modes. - Meta-Layer Commentary : short narrative explaining unspoken heuristics — how senior teams weigh risk tolerance, potency data, or tox uncertainty.
The client is seeking an external expert who brings a
- decision-maker’s mindset
- — someone who has personally driven translational pharmacology choices under governance and uncertainty.
###
Create a job alert for this search
Clinical Pharmacology • Urbana, Illinois, US
Related jobs
FlexCare is seeking an experienced Nuclear Medicine Technologist for an exciting Travel Allied job in Urbana, IL.Shift : 5x8 hr days Start Date : 12 / 22 / 2025 Duration : 26 weeks Pay : $2769.Level I Trau...Show more
Host Healthcare is seeking a travel Nuclear Medicine Technologist for a travel job in Urbana, Illinois.Job Description & Requirements.
Host Healthcare Job ID #a1fVJ000007zR45YAE.Pay package is based...Show more
LocumJobsOnline is working with CompHealth to find a qualified Emergency Medicine MD in Urbana, Illinois, 61801!.Some locum assignments can be as short as a day, others, years.Some are far from hom...Show more
Preferred Healthcare Staffing is seeking a travel Nuclear Medicine Technologist for a travel job in Urbana, Illinois.Job Description & Requirements.
Travel CT Technologist (CT) - Acute Care.Plea...Show more Host Healthcare is seeking a local contract Nuclear Medicine Technologist for a local contract job in Urbana, Illinois.Job Description & Requirements.
Host Healthcare Job ID #La1fVJ000007zR45YAE.Pay...Show more 
Aequor Allied is seeking a travel Nuclear Medicine Technologist for a travel job in Urbana, Illinois.Job Description & Requirements.
Pay package is based on 8 hour shifts and 40 hours per week (subj...Show more
LRS Healthcare - Allied is seeking an experienced Nuclear Medicine Technologist for an exciting Travel Allied job in Urbana, IL.
Shift : Inquire Start Date : 12 / 22 / 2025 Duration : 26 weeks Pay : $2724 / ...Show more
Are you a Urologist searching for your next perm position? This position with one of VISTA's healthcare partners in Urbana, Illinois might just be the opportunity for you Vertically integrated...Show more
DocCafe has an immediate opening for the following position : Physician - Hematology / Oncology in Urbana, Illinois.DocCafe is the premier physician and advanced practice job board to help you advance...Show more
LocumJobsNetwork is working with Curative to find a qualified Physical Medicine MD in Urbana, Illinois, 61801!.No Call PM&R - Inpatient Assignment in Illinois.
Seeking a Physical Medicine & ...Show more
Clinical Documentation Specialist Qualifications.License to practice as a Registered Nurse preferred (any state).Credentialed as a RHIA (Registered Health Information Administrator), RHIT (Register...Show more
Looking for a new Cytology Tech job? My name is Leah and I'm a healthcare recruiter, I'm here to help!.I have an awesome Cytology Tech role available near Humboldt, Illinois!.Full, comprehensive be...Show more
Client seeking an experienced full-time BC / BE Reproductive Endocrinologist to join their Division of Reproductive Medicine.
Practice opportunity details include : .Hospital based service with research...Show more
Excited to add BE / BC Hematology / Oncology Physicians with opportunity to specialize in his / her area of interest in oncology.
Hematology / Oncology Physicians would practice at our main campus with one ...Show more
CrossMed Healthcare is seeking an experienced Nuclear Medicine Technologist for an exciting Travel Allied job in Urbana, IL.
Shift : Inquire Start Date : 12 / 22 / 2025 Duration : 26 weeks Pay : $2604 / Wee...Show more
Pharmaceutical Sales Representative.We are a national healthcare company bring life-changing medicines to those who need them, as well as improve the understanding and management of disease.We give...Show more
Medical Experts - AI Training Role.Our client is a leading force in advancing safer, smarter AI technology.Their work has been featured in.
They have built a global community of expert contributors ...Show more
Christie Clinic in Champaign, IL, a physician-owned, physician-led, multi-specialty group is seeking providers who desire an autonomous environment offering leadership, team collaboration, and to b...Show more
Travel Nuclear Medicine Technologist - $2769.2 / Week
FlexCare • Urbana, IL, US
Full-time
Last updated: 2 days ago • Promoted
Travel Nuclear Medicine Technologist (PET / CT) - $2,826 per week
Host Healthcare • Urbana, IL, United States
Full-time
Last updated: 2 days ago • Promoted
Locum Physician (MD / DO) - Emergency Medicine in Urbana, IL
LocumJobsOnline • Urbana, IL, US
Full-time +1
Last updated: 30+ days ago • Promoted
Travel Nuclear Medicine Technologist
Preferred Healthcare Staffing • Urbana, IL, US
Full-time
Last updated: 1 day ago • Promoted
Local Contract Nuclear Medicine Technologist (PET / CT) - $59-63 per hour
Host Healthcare • Urbana, IL, United States
Full-time
Last updated: 2 days ago • Promoted
Travel Nuclear Medicine Technologist (PET / CT) - $2,812 per week
Aequor Allied • Urbana, IL, United States
Full-time
Last updated: 2 days ago • Promoted
Travel Nuclear Medicine Technologist - $2724 / Week
LRS Healthcare - Allied • Urbana, IL, US
Full-time
Last updated: 2 days ago • Promoted
Urology
VISTA Staffing Solutions • Urbana, US
Permanent
Last updated: 30+ days ago • Promoted
Hematology / Oncology Physician - Competitive Salary (Urbana)
DocCafe • Urbana, IL, US
Part-time
Last updated: 30+ days ago • Promoted
Locum Physician (MD / DO) - Physical Medicine - $225 to $260 per hour in Urbana, IL
LocumJobsNetwork • Urbana, IL, US
Full-time +1
Last updated: 30+ days ago • Promoted
Clinical Documentation Specialist - Remote (Must have CCDS OR CDIP)
Revolution Technologies • Champaign, IL, US
Remote
Full-time
Last updated: 30+ days ago • Promoted
Cytotechnologist or Cytotech in Illinois
KA Recruiting Inc. • Humboldt, IL, US
Full-time +1
Last updated: 19 hours ago • Promoted • New!
Endocrinologist - Reproductive Job
Continuum Medical Staffing • Urbana, IL, US
Full-time
Last updated: 30+ days ago • Promoted
Hematology / Oncology Physician
Arlington HealthCare • Urbana, IL, USA
Full-time
Last updated: 30+ days ago • Promoted
Travel Nuclear Medicine Technologist - $2604 / Week
CrossMed Healthcare • Urbana, IL, US
Full-time
Last updated: 1 day ago • Promoted
Oncology Rep Pharmaceutical
Innovativ Pharma, Inc. • Champaign, IL, United States
Full-time
Last updated: 4 days ago • Promoted
Medical Experts
Quality Talent Group • Urbana, Illinois, United States
Full-time
Quick Apply
Last updated: 7 days ago
Endocrinology Physician
Adkisson Search • Champaign, IL, USA
Full-time
Last updated: 30+ days ago • Promoted