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Upstream Process Engineer
Upstream Process EngineerHarba Solutions Inc. • Boston, MA, United States
Upstream Process Engineer

Upstream Process Engineer

Harba Solutions Inc. • Boston, MA, United States
2 days ago
Job type
  • Full-time
Job description

This range is provided by Harba Solutions Inc.. Your actual pay will be based on your skills and experience talk with your recruiter to learn more.

Base pay range

$110,000.00 / yr - $146,000.00 / yr

Direct message the job poster from Harba Solutions Inc.

Responsibilities

  • Independently design and execute experiments to optimize upstream manufacturing processes for viral vector production.
  • Perform statistical analysis of experimental data to identify trends and support process improvements.
  • Develop and apply empirical or theoretical models to predict process performance and enhance process understanding.
  • Evaluate, test, and implement innovative upstream technologies.
  • Collaborate cross-functionally with downstream process development, analytical development, and research teams to ensure high product quality and seamless process integration.
  • Provide technical support for the successful transfer of processes to contract manufacturing organizations.
  • Conduct routine cell culture operations, including bioreactor setup, probe calibration, maintenance, and cell culture passaging.
  • Manage experimental data, maintain accurate records using electronic notebooks, and generate comprehensive reports.
  • Perform sample analysis using various laboratory analytical tools.
  • Contribute to a collaborative team environment by sharing knowledge and supporting team goals.

Qualifications

  • PhD in Science, Engineering, or a related field with 2-5 years of experience; or MS with 5-8 years of experience.
  • Experienced with mammalian cell culture, bioreactors, AAV production, and upstream process development.
  • Knowledge of empirical or theoretical modeling, including machine learning or statistical methods.
  • Strong analytical and problem-solving skills.
  • Effective communication, organizational, and collaboration abilities.
  • Flexibility to work occasional weekends (for active cell culture).
  • Familiarity with transient transfections, AAV, automation, and technology transfer is preferred.
  • The Company

    Unlock the opportunity to revolutionize viral vector production in a cutting-edge upstream process development role. Collaborate with a dynamic team to optimize manufacturing processes, integrate innovative technologies, and drive impactful projects. With your expertise in cell culture, bioreactors, and process modeling, youll play a key role in advancing groundbreaking therapies. Take the next step in your career and make a lasting impact in a rapidly growing field!

    Seniority level

    Mid-Senior level

    Employment type

    Full-time

    Job function

    Science, Research, and Engineering

    Industries

    Biotechnology Research, Pharmaceutical Manufacturing, and Manufacturing

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