Lead Researcher Antibody Discovery

The Lead Researcher for Antibody Discovery performs a variety of basic laboratory research tasks determined by the field and scope of the particular research project / study within HMI.

Join an excellent team of researchers dedicated to coming closer to the mission of St. Jude Childrens Research Hospital that no child will die at the dawn of life. Antibody Discovery Collaborative Centre (ADCC) within the Department of Host Microbe Interactions at St. Jude seeks a skilled and highly motivated protein sciences candidate with experience in gene-to-protein workflows . This role will be responsible for developing and implementing strategies that improve the efficiency scalability and fidelity of molecular biology processes ensuring that downstream teams receive high-quality protein and biologics for discovery purposes.

Candidates with experience in protein engineering expression and validation of biologics are encouraged to apply . Masters degree in relevant scientific area with proven performance in earlier role (3 years) OR PhD with suitable graduate training will be preferred.

What you will do :

• Work closely with mAb discovery platforms to support molecular biology workflows; design and execute construct generation for antibody expression.
• Perform DNA preparations to generate high-quality plasmid material for mammalian cell transfection.
• Develop and optimize high-throughput mammalian cell-based production platforms for recombinant antibodies antigens and other biologics.
• Establish scalable transient and stable expression workflows in CHO HEK293 and other mammalian expression systems.
• Purification using AKTA chromatography systems.
• High-Performance Liquid Chromatography Size Exclusion Chromatography (HPLC-SEC) analysis of purified proteins.
• Molecular assessment of early-stage development candidates (polyreactivity ELISA CE-SDS SEC-MALS DSF)
• Maintain accurate and timely ELN data

Preferred skills :

About St. Jude

St. Jude Childrens Research Hospital is a world-class research institution dedicated to pediatric cancer and other catastrophic diseases of childhood. The first and only National Cancer Institute (NCI)-designated Comprehensive Cancer Center devoted solely to children. Our 300 faculty work across the spectrum of basic translational clinical and population science in a highly collaborative multidisciplinary environment that includes a Nobel laureate and members of the National Academy of Science and the National Academy of Medicine. St. Jude is ranked on Fortune Magazines Best Workplaces in Health Care & Biopharma and Glassdoors Best Places to Work. St. Jude is one of the best-funded research institutes in the US with an annual budget of over $2 billion per year ( We Will Offer You

Working at St. Jude is a remarkable experience in many ways and you will be provided with many special perks.

St. Jude is located in the heart of Memphis Tennessee a vibrant and friendly city at the historic American crossroads of music trade food and culture. Living in Memphis provides several unique advantages including :

Breathtaking Nature : Memphis provides unique nature and scenery such as the Mississippi (the largest river in the US) or Shelby Farms Park with which 4500 acres is one of the largest urban parks in the country. See for more details.

Bachelors degree in a relevant scientific area is required

Minimum Experience :

Compensation

In recognition of certain U.S. state and municipal pay transparency laws St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets experience and training licensure and certifications and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $60320 - $105040 per year for the role of Lead Researcher Antibody Discovery.

Explore our exceptional benefits!

St. Jude is an Equal Opportunity Employer

No Search Firms

St. Jude Childrens Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email the internet or in any form and / or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Key Skills

Intelligence Community Experience,Python,Spss,Microsoft Word,R,Regression Analysis,Windows,Stata,Microsoft Powerpoint,Research Experience,Data Modeling,Writing Skills

Employment Type : Full-Time

Experience : years

Vacancy : 1

Yearly Salary Salary : 60320 - 105040