Senior Director / Vice President, Computational Test Development

The Opportunity

We are seeking a senior level computational biology / bioinformatics scientist with background in diagnostic test development and a focus on NGS and ideally epigenomic modalities. This role is responsible for the data analysis and development aspects of clinical diagnostic test development for a novel blood-based epigenomic platform, as well as analysis relating to the development of the platform itself. This is a unique opportunity for someone passionate about pushing the boundaries of diagnostic testing, building novel diagnostic tests and methods for assay characterization and optimization, and ultimately improving data interpretation to create better predictors and diagnostics. If you're excited about joining an early-stage company with an experienced team operating at a rapid pace, and applying a novel platform for clinical diagnostics testing, this could be your perfect match.

About Us

We are pioneering an advanced, minimally invasive, comprehensive epigenomics platform with the potential to profoundly impact the research and development of new medicines and the use of approved medicines in clinical practice across a number of conditions, including cancer. More information on our company and platform can be found on our company website and in our recent publication in Nature Medicine.

We care deeply about creating a place where folks can do their best work from the start and have intentionally created an environment that is defined by purpose, teamwork, and excellence. This means nurturing team spirit, facing challenges together, collaboratively solving complex problems, while also ensuring a strong focus on individual initiative, accountability, and delivery.

What You’ll Do

• Develop computational approaches for characterizing the performance of existing and new epigenomic assays and tests.
• Define and implement metrics and analyses to assess NGS and epigenomic data quality to enable coordinated optimization of assay and diagnostic performance to address test requirements.
• Assume responsibility for the computational aspects of late-stage development and validation of novel epigenomic liquid biopsy diagnostic tests.
• Take part in design and execution of validation studies of epigenomic-based diagnostic tests for use in a regulated clinical lab.
• Share data driven insights of test and assay performance with leadership and wet lab development teams to inform assay development priorities.
• As a key member of a cross‑functional team, you will work closely with various stakeholders, especially those within our platform development laboratory team and regulatory team, to make innovative diagnostics a reality.

Who You Are

We believe in building an inclusive and balanced team. We also know meeting every single‑exact‑criteria can get in the way of meeting stellar folks. Please don’t hesitate to apply!

We are an equal opportunity employer. We do not discriminate in regard to race, color, religion, national origin, age, sex, sexual orientation, gender identity, marital status, ancestry, physical or mental disability, veteran status, or any other legally protected characteristics.

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