PK/PD Modeling / Pharmacometrics LeadMercor • Beaumont, California, US
No longer accepting applications
PK / PD Modeling / Pharmacometrics Lead
Mercor • Beaumont, California, US
1 day ago
Job type
- Part-time
- Remote
Job descriptionWho we’re looking for Deep hands-on experience in PK, PD, exposure–response modeling , and ideally population PK or QSP . - Expert at model fitting, sensitivity analysis, and identifying non-plausible parameter spaces. - Can evaluate the validity of dose–exposure predictions and detect high-risk extrapolations. - Comfortable designing model evaluation rubrics that distinguish between acceptable vs. non-credible outputs. - Able to articulate how quantitative checks should complement narrative decision logic. Nice-to-have : Experience supporting translational or clinical pharmacology leads in dose justification. - Familiarity with integrating nonclinical PK / PD data (2-species GLP → human FIH extrapolation). ### Experience level ~8–12 years of quantitative pharmacology experience in pharma, CROs, or modeling consultancies . - Strong portfolio in population PK / PD exposure–response , and parameter estimation using NONMEM, Monolix, or equivalent tools. - Demonstrated ability to interpret model results for decision-making, not just fit data. - Can create fit-for-purpose models and critique model structures or assumptions under uncertainty. ### Expectations Design and refine micro-evaluations for PK / PD performance (curve fits, parameter checks, error taxonomies). - Encode quantitative sanity checks into model rubrics for automated evaluation. - Define failure conditions (e.g., unsafe extrapolation, poor coverage curves, invalid assumptions). Inputs we give : PK / PD datasets, tox summaries, and performance prompts (e.g., “fit exposure–response curves, interpret safety margins”). - Example model outputs from automated systems. Expected outputs : Quantitative Rubrics : clear thresholds for acceptable parameter fits, coverage curve quality, and model integrity checks. - Golden Fit Examples : representative “ideal” PK / PD model outputs and visualizations for calibration. - Error Taxonomy : structured list of typical modeling or fitting errors, with root-cause annotations. - Meta-Layer Commentary : short note per rubric capturing how expert modelers recognize implausible or unsafe fits beyond numeric error values. ### Engagement Model & Compensation Contract / part-time , remote, outcome-based deliverables.
This person complements the client’s “Translational / Clinical Pharmacology Decision-Maker” team by grounding dose selection and exposure–response analysis in
- quantitative structure and parameter plausibility
###
Create a job alert for this search
Modeling • Beaumont, California, US
Related jobs
AlliedTravelCareers is working with Prime HealthCare Staffing to find a qualified Physical Therapist (PT) in Hemet, California, 92543!.
Prime HealthCare Staffing, a national health care staffing com...Show more AlliedTravelCareers is working with Windsor Healthcare Recruitment Group, Inc.Physical Therapist (PT) in Big Bear Lake, California, 92315!.
Evaluates, plans, directs and administers medically prescr...Show more 
Powerback - Contract - Hemet CA.Stay updated with job opportunities from Talent4Health that match your skills! You can reply "STOP" anytime to unsubscribe or send e-mail at nexusqueries@talent4health.Show more
Our client is a leading force in advancing safer, smarter AI technology.Their work has been featured in.They’ve built a global community of expert contributors and have already paid out more ...Show more
Our Client is currently seeking Physical Therapist for positions in Hemet, CA for a 5×8 Days shift.The ideal candidate will possess a current CA license or Compact license Depending on the state.Yo...Show more
DocCafe has an immediate opening for the following position : Physician - Pediatrics in Hemet, California.DocCafe is the premier physician and advanced practice job board to help you advance your he...Show more
Estimated Gross Weekly Wage $2083.A valid license in the state of practice.Strong communication, organizational, and interpersonal skills are essential.
Must be able to interact effectively with pat...Show more
We are looking for a Physical Therapist (PT) for an immediate travel opening in Hemet, CA.The right PT should have 1 year of experience.
for an exceptional candidate with an appropriate background,...Show more
California Physical Therapist License.We are an equal opportunity employer.Show more
Triage Staffing is seeking a travel Physical Therapist for a travel job in Hemet, California.Job Description & Requirements.
Travel Rehab : Physical Therapy Hemet.Shift Details : 8H Days (12 : 00 AM-1...Show more
AlliedTravelNetwork is working with AMN Healthcare Allied to find a qualified Physical Therapist (PT) in HEMET, California, 92544!.
Job Description & Requirements.Physical Therapist - Skilled - ...Show more
Medical Director (DVM) – Beaumont, CA.A well‑established small animal practice in Beaumont, California is seeking an experienced and motivated Medical Director to lead its clinical team.This positi...Show more
Powerback - Contract - Devonshire Care Cent -R05A15.All shown pay is an estimate based on pay package configuration, please apply now to learn more.Show more
Our client in Hemet CA has a (CA) 8HR DAY travel position for an Therapist traveler with current Physical Therapy - PT experience.
The ideal candidate must have at least 2 years of experience, with ...Show more
Job Description & Requirements.Physical Therapist - Skilled - (PT - Skilled) .StartDate : 12 / 15 / 2025 Available Shifts : 8 D Pay Rate : $2121.
Physical therapists (PTs) are health care professiona...Show more![Physical Therapist [SCAL Posting]](https://cdn-logos.talent.com/v1/logo/image?feedcode=thecareersphere&company_name=Interface%20rehab%2C%20inc.)
Salary Range : Dependent upon experience, schedule, location, and employee classification from $45.California with expertise in Post-Acute Care, retirement communities, and outpatient clinics.We inv...Show more
Genie Healthcare is seeking a travel Physical Therapist for a travel job in Hemet, California.Job Description & Requirements Specialty : Physical Therapist Discipline : Therapy Start Date : 12 / 22 / 2025...Show more Medical Director (DVM) – Beaumont, CA.A well‑established small animal practice in Beaumont, California is seeking an experienced and motivated Medical Director to lead its clinical team.This positi...Show more
Travel Physical Therapist (PT) - $1,929 per week in Hemet, CA
AlliedTravelCareers • Hemet, CA, US
Full-time
Last updated: 30+ days ago • Promoted
Travel Physical Therapist (PT) in Big Bear Lake, CA
AlliedTravelCareers • Big Bear Lake, CA, US
Full-time
Last updated: 30+ days ago • Promoted
PT
Powerback - Contract - Hemet CA • Hemet, CA, United States
Full-time
Last updated: 30+ days ago • Promoted
Engineer
Quality Talent Group • Hemet, California, United States
Full-time
Quick Apply
Last updated: 8 days ago
PT Physical Therapist
Specialty Professional Services, Corp. • Hemet, CA, United States
Full-time
Last updated: 30+ days ago • Promoted
Pediatrics Physician - Competitive Salary (Hemet)
DocCafe • Hemet, CA, US
Part-time
Last updated: 30+ days ago • Promoted
Physical Therapist
White Glove Placement • Hemet, CA, United States
Permanent
Last updated: 30+ days ago • Promoted
Travel Allied - Physical Therapist
Travel Nurse Across America • Hemet, CA, United States
Full-time
Last updated: 5 days ago • Promoted
Physical Therapy - PT SNF
Devonshire Care Center • Hemet, CA, United States
Full-time
Last updated: 30+ days ago • Promoted
Travel Physical Therapist - $2,369 per week
Triage Staffing • Hemet, CA, USA
Full-time
Last updated: 30+ days ago • Promoted
Travel Physical Therapist (PT) - $2,121 to $2,324 per week in Hemet, CA
AlliedTravelNetwork • HEMET, CA, US
Full-time
Last updated: 2 days ago • Promoted
Medical Director (DVM) – Rewarding Role with Growth Potential, Beaumont, CA
Desort • Beaumont, CA, United States
Full-time
Last updated: 18 days ago • Promoted
Physical Therapy - PT SNF
Powerback - Contract - Devonshire Care Cent -R05A15 • Hemet, CA, United States
Full-time
Last updated: 5 days ago • Promoted
Physical Therapy Therapist
GO Healthcare Staffing • Hemet, CA, United States
Full-time
Last updated: 30+ days ago • Promoted
Travel Physical Therapist (PT) - $2,121 to $2,324 per week in Hemet, CA
AMN Healthcare Allied • HEMET, CA, US
Full-time
Last updated: 2 days ago • Promoted
Physical Therapist [SCAL Posting]
Interface rehab, inc. • Hemet, CA, United States
Full-time +2
Last updated: 30+ days ago • Promoted
Travel Physical Therapist - $2,574 per week
Genie Healthcare • San Jacinto, CA, United States
Full-time
Last updated: 1 day ago • Promoted
Medical Director (DVM) – Leadership Opportunity + Great Pay + Work-Life Balance, Beaumont, CA
Desort • Beaumont, CA, United States
Full-time
Last updated: 18 days ago • Promoted