Senior Director, Translational Medicine, CNS - Early Development

Job Summary

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The Senior Director will serve as the Translational Medicine CNS Therapeutic Area Head, reporting to the VP, Translational Medicine and Early Clinical Development within OPDC’s Early Development Organization (EDO). The Senior Director Translational Medicine will oversee a small team of CNS Translational Medicine Experts reporting to her / him on the early development CNS portfolio and Early Development Teams. This Senior Director is a strategic scientific and clinical leader accountable for the end-to-end translational strategy and execution for Otsuka's early phase portfolio, with emphasis on CNS, particularly psychiatry, neurodegenerative disease, and neuroinflammation. The role shapes program strategy from indication selection through early clinical development (pre-IND through first-in-human and clinical proof of concept), and go / go no decisions based on clinical and / or biomarker driven endpoints ensuring seamless integration across discovery, nonclinical, clinical pharmacology, regulatory, and commercial functions. As an industry-leading expert and trusted advisor to senior leadership, this leader directs complex, cross-functional initiatives with enterprise impact, and helps define the operating model and culture of the EDO.

Key Responsibilities

Enterprise and Portfolio Leadership

• Serve as subject matter expert and thought leader in areas of strategic importance to Otsuka; act as a trusted advisor to senior leadership on early development strategy in the CNS space.
• Lead CNS TM team on complex, business-critical programs with enterprise impact; shape portfolio strategy and influence resource allocation for Otsuka's early phase assets.
• Drive Research-to-Development (R2D) strategies and stage-gate decision-making, including indication prioritization and go / no-go based on mechanistic rationale, benefit-risk, and clinical unmet need as well as on clinical and / or biomarker driven endpoints.
• Serve as a functional cultural ambassador, modeling EDO Ways of Working and fostering a high-performance, inclusive, and learning-oriented environment.

Translational and Clinical Development

Cross-Functional and Governance Leadership

External Innovation and Business Development

People and Organizational Leadership

Compliance, Quality, and Risk Management

Qualifications

Required

Preferred