Talent.com
Director, Translational Medicine
Director, Translational MedicineVor Bio • Boston, MA, US
Director, Translational Medicine

Director, Translational Medicine

Vor Bio • Boston, MA, US
15 days ago
Job type
  • Full-time
Job description

Director Of Translational Medicine

Join us in tackling autoimmune disease at its root.

At Vor, we believe science can do more than manage symptoms. It can change the course of disease. By advancing telitacicept, a first- and potentially best-in-class dual BAFF / APRIL inhibitor, we are silencing upstream survival signals and stopping downstream autoimmune cascades. Together, we are addressing disease at its root cause and rewriting what is possible for patients worldwide.

When you join Vor, you're not just working on a medicine. You're part of a mission to redefine the future of autoimmune care.

Why work at Vor?

Impact : Contribute directly to a medicine with best-in-disease Phase 3 results in myasthenia gravis and expansion into multiple autoimmune diseases.

Growth : Be part of a rapidly scaling company with opportunities to grow your career in science, clinical development, commercial strategy, and beyond.

Innovation : Work on a platform with potential beyond one indication a therapy that has already shown consistent results across lupus, IgA nephropathy, and Sjgren's syndrome.

Belonging : Join a culture where every voice is heard, and where our shared mission unites us across functions and geographies.

We are seeking a visionary and scientifically driven Director of Translational Medicine to lead the strategic integration of preclinical and clinical research, accelerating the development of innovative therapies from bench to bedside. This leadership role bridges discovery science and clinical application, ensuring that our R&D pipeline is informed by cutting-edge translational insights and patient-centric strategies.

Key responsibilities :

  • Strategic leadership : Define and execute the translational medicine strategy across therapeutic programs, aligning with corporate R&D goals.
  • Biomarker development : Oversee the identification, validation, and implementation of predictive, pharmacodynamic, and safety biomarkers.
  • Clinical-preclinical integration : Translate preclinical findings into clinical hypotheses and study designs; ensure bidirectional flow of insights between lab and clinic.
  • Cross-functional collaboration : Partner with discovery, preclinical toxicology, clinical development, regulatory, bioinformatics, and commercial teams to drive data-informed decision-making.
  • External engagement : Build and maintain relationships with academic collaborators, CROs, consortia, and regulatory bodies to advance translational objectives.
  • Data strategy : Guide the integration of multi-omics, imaging, and real-world data to inform patient stratification and therapeutic response.
  • Team leadership : Mentor and lead a high-performing team of translational scientists and project leads.

Qualifications :

  • PhD, MD, or MD / PhD in a relevant scientific discipline (e.g., immunology, oncology, neuroscience, pharmacology).
  • 10+ years of experience in translational medicine, clinical development, or related R&D roles in biotech / pharma.
  • Proven track record of advancing drug candidates through late phase clinical development (Phase IIIII).
  • Deep understanding of biomarker science, clinical trial design, and regulatory considerations.
  • Strong leadership, communication, and cross-functional collaboration skills.
  • Experience with omics technologies, bioinformatics, and data integration is highly desirable.
  • Preferred attributes :

  • Therapeutic area expertise in autoimmune, immunology, and / or rare diseases.
  • Experience working in fast-paced, innovative biotech environments.
  • Familiarity with regulatory submissions (e.g., IND, CTA, BLA) and companion diagnostics development.
  • The salary range for this position is expected to be between $225,854 and $239,439 per year. Individual pay may vary based on multiple factors including but not limited to relevant job-related skills, experience, education or training, market factors, and work location.

    At Vor, we support our team with robust benefits, including comprehensive health coverage, flexible paid time off, generous parental leave, and a competitive 401(k). From education assistance to wellness resources and financial security, we invest in your well-being so you can thrive at work and beyond.

    As an equal opportunity employer, we at Vor Bio know that diversity inspires innovation, inclusiveness, and creativity. We invite you to come as you are. All applicants will be considered for employment agnostic to race, age, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

    Create a job alert for this search

    Director Translational Medicine • Boston, MA, US

    Related jobs
    Global Medical Director, Povetacicept

    Global Medical Director, Povetacicept

    Ccrps • Boston, MA, United States
    Full-time
    General Summary : The Global Medical Affairs Strategy Medical Director will provide medical leadership for the Povetacicept programs. Povetacicept (pove) is an enhanced, dual BAFF / APRIL inhibitor in ...Show more
    Last updated: 8 days ago • Promoted
    Associate Director, Clinical and Translational Imaging

    Associate Director, Clinical and Translational Imaging

    Novartis Group Companies • Cambridge, MA, United States
    Full-time
    The Biomarker Development (BMD) group at the Novartis Institutes for BioMedical Research (NIBR) is seeking a Senior Expert Imaging to join our Clinical Imaging team and actively provide strategic, ...Show more
    Last updated: 1 day ago • Promoted
    Director - In Vivo Pharmacology

    Director - In Vivo Pharmacology

    Eli Lilly and • Boston, MA, United States
    Full-time
    At Lilly, we unite caring with discovery to make life better for people around the world.We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work...Show more
    Last updated: 12 days ago • Promoted
    Global Medical Director, Povetacicept

    Global Medical Director, Povetacicept

    Teredesai, McCann & Assoc • Boston, MA, United States
    Full-time
    General Summary : The Global Medical Affairs Strategy Medical Director will provide medical leadership for the Povetacicept programs. Povetacicept (pove) is an enhanced, dual BAFF / APRIL inhibitor in ...Show more
    Last updated: 3 days ago • Promoted
    Medical Director, North America

    Medical Director, North America

    Cedent Consulting • Boston, MA, United States
    Full-time
    As Medical Director in North America Medical Affairs, you will be a strategic thought partner providing expert medical leadership and launch excellence, leading Medical Affairs strategy, content de...Show more
    Last updated: 30+ days ago • Promoted
    Director of Endocrinology

    Director of Endocrinology

    Signature Healthcare • Brockton, US
    Full-time
    Come join our team at Signature Healthcare! This is a great opportunity for a BC Endocrinologist that thrives on providing excellent patient care and has an interest in clinical leadership.Our team...Show more
    Last updated: 30+ days ago • Promoted
    OBGYN Director | Near Portland, OR | $100,000 Sign-On

    OBGYN Director | Near Portland, OR | $100,000 Sign-On

    Jackson Physician Search • Salem, US
    Full-time
    A large community hospital 45 minutes from Portland, OR is searching for a physician leader to oversee Women's Services.The typical schedule consists of 3 days in clinic, 1 OR day, and 1 dedicated ...Show more
    Last updated: 30+ days ago • Promoted
    Medical Director, Rheumatology

    Medical Director, Rheumatology

    argenx • Boston, MA, United States
    Full-time
    Join us as we transform immunology and deliver medicines that help autoimmune patients get their lives back.VYVGART, our first-in-class neonatal Fc receptor blocker approved for the treatment of gM...Show more
    Last updated: 12 days ago • Promoted
    Global Translational Medicine Lead - Ophthalmology

    Global Translational Medicine Lead - Ophthalmology

    Astellas • Cambridge, MA, United States
    Full-time
    Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patien...Show more
    Last updated: 30+ days ago
    Medical Director, Rheumatology

    Medical Director, Rheumatology

    argenx SE • Boston, MA, United States
    Full-time
    VYVGART, our first-in-class neonatal Fc receptor blocker approved for the treatment of gMG, and with the potential to treat patients across dozens of severe autoimmune diseases.We are building a ne...Show more
    Last updated: 13 days ago • Promoted
    Global Senior Medical Director, Solid Tumor Oncology

    Global Senior Medical Director, Solid Tumor Oncology

    Takeda Pharmaceuticals • Boston, MA, United States
    Full-time
    A leading global pharmaceutical company is seeking a Senior Medical Director in Boston, MA to lead clinical development strategies for multiple pipeline compounds. The ideal candidate will have exte...Show more
    Last updated: 6 hours ago • Promoted • New!
    Global Medical Director, Povetacicept

    Global Medical Director, Povetacicept

    Vertex Pharmaceuticals • Boston, MA, United States
    Full-time
    General Summary : The Global Medical Affairs Strategy Medical Director will provide medical leadership for the Povetacicept programs. Povetacicept (pove) is an enhanced, dual BAFF / APRIL inhibitor in ...Show more
    Last updated: 13 days ago • Promoted
    Senior Medical Director

    Senior Medical Director

    Zevra Therapeutics, Inc. • Boston, MA, United States
    Full-time
    We are a rare disease therapeutics company leading with science to make life-changing therapeutics available to patients with significant unmet needs. We involve key thought leaders, physicians, pat...Show more
    Last updated: 30+ days ago • Promoted
    Medical Director

    Medical Director

    Highmark Health • Boston, MA, United States
    Full-time
    JOB SUMMARY : This job, as part of a physician team, ensures that utilization management responsibilities are performed in accordance with the highest and most current clinical standards.The incumbe...Show more
    Last updated: 30+ days ago • Promoted
    Lead Medical Director, Product Development, Hematology / Oncology

    Lead Medical Director, Product Development, Hematology / Oncology

    Genentech • Boston, MA, United States
    Full-time
    Lead Medical Director, Product Development, Hematology / Oncology.We advance science so that we all have more time with the people we love. Roche's Clinical Development organization is structured by t...Show more
    Last updated: 30+ days ago • Promoted
    Director, Toxicology

    Director, Toxicology

    Editas Medicine • Cambridge, MA, US
    Full-time
    Quick Apply
    At Editas Medicine, we are pioneering the possible.Our mission and commitment is to translate the power and potential of the CRISPR / Cas12a and CRISPR / Cas9 genome editing systems into a robust pipel...Show more
    Last updated: 30+ days ago
    Regional Medical Scientific Director, Pulmonary Hypertension (Remote : Colorado, Kansas, New Mex[...]

    Regional Medical Scientific Director, Pulmonary Hypertension (Remote : Colorado, Kansas, New Mex[...]

    Merck • Boston, MA, United States
    Remote
    Full-time
    We are seeking a Growth and Improvement minded Regional Medical Scientific Director | Cardiopulmonary & Pulmonary Hypertension that can help drive our Strategic Operating Priorities.Invent | Pursue...Show more
    Last updated: 6 hours ago • Promoted • New!
    Endocrinology, Salem, MA

    Endocrinology, Salem, MA

    Mass General Brigham • Salem, US
    Full-time +1
    Mass General Brigham is seeking a Board Certified or Board Eligible Endocrinologist with experience / special interest in Transgender care to join our multidisciplinary practice in Salem, Massachuset...Show more
    Last updated: 30+ days ago • Promoted