Director Clinical Operations

Director, Clinical Operations

San Diego, CA - Onsite

$180,000-$2100,000

An emerging biotech company in San Diego is seeking a Director of Clinical Operations to lead early-stage clinical programs in the cardiology space. The company is advancing a novel therapeutic platform focused on gene regulation, with applications in complex diseases such as fibrosis and oncology.

This role will be responsible for overseeing clinical trial execution from start-up through completion, including vendor and CRO management, cross-functional coordination, and operational strategy. The ideal candidate will bring strong leadership in trial design, site engagement, and regulatory compliance, along with a hands-on approach to building clinical infrastructure in a fast-paced, science-driven environment.

Key Responsibilities :

• Lead execution of Phase 1 and 2 trials, including investigator-initiated studies
• Collaborate on protocol development and trial design
• Manage CROs, vendors, and external partners
• Coordinate across clinical science, regulatory, biostats, and other functions
• Oversee drug supply logistics and biospecimen management
• Develop and implement enrollment strategies and patient-facing materials
• Ensure GCP / ICH compliance and clinical quality systems
• Support safety monitoring and pharmacovigilance activities
• Manage study budgets, site payments, and financial tracking
• Serve as primary liaison for clinical sites and oversee site performance
• Contribute to data integrity, interim analyses, and reporting

Qualifications