Description
Key Responsibilities
- Apply cryo-EM and/or X-ray crystallography to determine high-resolution structures of proteins and macromolecular complexes relevant to drug discovery
- Conduct cryo-EM workflows including grid preparation, data collection, image processing, 3D reconstruction, and model building
- Collaborate closely with cross-functional teams to integrate structural insights into medicinal chemistry and biologics design efforts including hit validation and hit-to-lead optimization.
- Contribute to the operation, optimization, and maintenance of cryo-EM instrumentation and workflows
- Present results clearly to internal project teams and contribute to scientific publications and reports
- Independently manage multiple projects in a fast-paced environment and deliver impactful results
Basic Qualifications
- PhD in Structural Biology or related field with postdoctoral training in solving atomic resolution structures of macromolecular complexes
- Minimum of 3 years of relevant experience in structural biology, preferably including biopharmaceutical industry experience
Preferred Qualifications
- Extensive experience in single-particle cryo-EM, including grid preparation, optimization, data acquisition, processing, 3D reconstruction, and model building
- Hands-on experience in recombinant protein construct design, expression, purification, and characterization
- Excellent communication, collaboration, and interpersonal skills in a matrixed team environment
- Strong organizational skills with the ability to manage multiple projects independently
The salary range for this position is: $169,320.00 - $219,120.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.
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* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.
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Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact for assistance.