PK/PD Modeling / Pharmacometrics LeadMercor • Weslaco, Texas, US
No longer accepting applications
PK / PD Modeling / Pharmacometrics Lead
Mercor • Weslaco, Texas, US
1 day ago
Job type
- Part-time
- Remote
Job descriptionWho we’re looking for Deep hands-on experience in PK, PD, exposure–response modeling , and ideally population PK or QSP . - Expert at model fitting, sensitivity analysis, and identifying non-plausible parameter spaces. - Can evaluate the validity of dose–exposure predictions and detect high-risk extrapolations. - Comfortable designing model evaluation rubrics that distinguish between acceptable vs. non-credible outputs. - Able to articulate how quantitative checks should complement narrative decision logic. Nice-to-have : Experience supporting translational or clinical pharmacology leads in dose justification. - Familiarity with integrating nonclinical PK / PD data (2-species GLP → human FIH extrapolation). ### Experience level ~8–12 years of quantitative pharmacology experience in pharma, CROs, or modeling consultancies . - Strong portfolio in population PK / PD exposure–response , and parameter estimation using NONMEM, Monolix, or equivalent tools. - Demonstrated ability to interpret model results for decision-making, not just fit data. - Can create fit-for-purpose models and critique model structures or assumptions under uncertainty. ### Expectations Design and refine micro-evaluations for PK / PD performance (curve fits, parameter checks, error taxonomies). - Encode quantitative sanity checks into model rubrics for automated evaluation. - Define failure conditions (e.g., unsafe extrapolation, poor coverage curves, invalid assumptions). Inputs we give : PK / PD datasets, tox summaries, and performance prompts (e.g., “fit exposure–response curves, interpret safety margins”). - Example model outputs from automated systems. Expected outputs : Quantitative Rubrics : clear thresholds for acceptable parameter fits, coverage curve quality, and model integrity checks. - Golden Fit Examples : representative “ideal” PK / PD model outputs and visualizations for calibration. - Error Taxonomy : structured list of typical modeling or fitting errors, with root-cause annotations. - Meta-Layer Commentary : short note per rubric capturing how expert modelers recognize implausible or unsafe fits beyond numeric error values. ### Engagement Model & Compensation Contract / part-time , remote, outcome-based deliverables.
This person complements the client’s “Translational / Clinical Pharmacology Decision-Maker” team by grounding dose selection and exposure–response analysis in
- quantitative structure and parameter plausibility
###
Create a job alert for this search
Modeling • Weslaco, Texas, US
Related jobs
Physical Therapist (PT) at Care Options for Kids summary : .As a Physical Therapist (PT) in Weslaco, TX, you will have the opportunity to significantly impact children's lives through high-quality pe...Show more
About Us : MRG Exams is a premier provider of independent medical examinations, dedicated to supporting United States Veterans through the VA's disability benefits process.Our mission is to deliver ...Show more
Join an award-winning team of dedicated professionals committed to our core values of quality, compassion, and community! Knapp Medical Center, a member of the Prime Healthcare Foundation, offers i...Show more
We are seeking a Physical Therapist , sometimes referred to as a Movement Specialist.The Physical Therapist (PT ) will help patients regain mobility and function after illness, injury, or surgery t...Show more
Top-Paying Reefer OTR Positions Now Available at APL Cargo.Average 2,500 - 3,500 Weekly Miles.Start at 60 CPM - Earn $78,000 - $109,200 per year.
Up to 2 CPM performance bump after 90 days.Up to 2 C...Show more
Our client is a leading force in advancing safer, smarter AI technology.Their work has been featured in.They’ve built a global community of expert contributors and have already paid out more ...Show more
LRS Healthcare - Allied is seeking an experienced CT Tech for an exciting Travel Allied job in Weslaco, TX.Shift : Inquire Start Date : ASAP Duration : 13 weeks Pay : $2590 / Week.Ready to start your n...Show more
Physical Therapy Assistant (PTA).We're seeking Physical Therapy Assistants looking for an opportunity to work with experienced Physical Therapists dedicated to their patients and their assistan...Show more
MSSI is seeking a travel CT Technologist for a travel job in Weslaco, Texas.Job Description & Requirements.Pay package is based on 12 hour shifts and 36 hours per week (subject to confirmation) wit...Show more
Certified Medication Aide (CMA) – Join Our Compassionate Care Team! .ALFREDO GONZALEZ TEXAS STATE VETERANS HOME- MCALLEN, TX.
MUST HAVE VALID CNA and Medication Aide certifications in TX • •.FULL TIM...Show more
POSITION SUMMARY : Clinical Pharmacist will act as Pharmacist-in-Charge for Free Standing Emergency Departments.As PIC, pharmacist will be responsible for compliance with Class F laws and rules per...Show more
QuickMD is a leading telemedicine provider, delivering high-quality virtual care across 44 states.Since our founding in 2019, we have helped more than 100,000 patients access essential medical trea...Show more
Physical Therapist (PT) at Care Options for Kids Careers summary : .The Physical Therapist (PT) plays a vital role in enhancing the well-being of children through flexible, community-focused care.Thi...Show more
Are you a forward-thinking and passionate Physical Therapist looking for an opportunity to make a meaningful impact on the lives of children in your community? This is an opportunity to create a ba...Show more At Care Options for Kids, a pediatric home health care company providing one-on-one care in the home, we do things a little differently.
There's no revolving door of patients or hospital setting...Show more Medical Experts - AI Training Role.Our client is a leading force in advancing safer, smarter AI technology.Their work has been featured in.
They have built a global community of expert contributors ...Show more 
Schedule : Flexible, up to 40 hours per week.Setting : Nursing Home, Rehabilitation Center, Skilled Nursing Facility.Location : Mid Valley Nursing & Rehabilitation - Mercedes, TX.We invest in your fut...Show more
HonorVet Technologies is seeking a travel CT Technologist for a travel job in Weslaco, Texas.Job Description & Requirements.
Tech that can do both cat scan and x-ray.Shift Time : 7pm – 7am,...Show more
Physical Therapist (PT)
Care Options for Kids • WESLACO, TX, USA
Full-time
Last updated: 30+ days ago • Promoted
Physical Medicine and Rehabilitation Doctor - McAllen TX
MRG Exams • Weslaco, TX, United States
Part-time
Last updated: 30+ days ago • Promoted
Patient Care Assist (PCA) 12 Hr - KMC Medical Surgical Acute
Knapp Medical Center • Weslaco, TX, United States
Full-time
Last updated: 2 days ago • Promoted
Physical Therapist - Rehab
Prime Healthcare • Weslaco, TX, United States
Full-time
Last updated: 30+ days ago • Promoted
2+ Yrs Exp. OTR CDL-A Drivers - Earn $78,000-$109,200 / Year + Benefits
APL Cargo, Inc. • Weslaco, TX, United States
Full-time
Last updated: 1 hour ago • Promoted • New!
Engineer
Quality Talent Group • Weslaco, Texas, United States
Full-time
Quick Apply
Last updated: 8 days ago
Travel CT Tech - $2590 / Week
LRS Healthcare - Allied • Weslaco, TX, US
Full-time
Last updated: 3 days ago • Promoted
Physical Therapy Assistant (PTA)
Care Options for Kids • Weslaco, TX, US
Part-time
Last updated: 30+ days ago • Promoted
Travel CT Technologist - $2,758 per week
MSSI • Weslaco, TX, United States
Full-time
Last updated: 17 days ago • Promoted
Certified Medication Aide
Touchstone Communities • Weslaco, TX, United States
Full-time
Last updated: 10 days ago • Promoted
Supervisor Pharmacy FT Weslaco
Universal Health Services, Inc. • Weslaco, TX, United States
Full-time
Last updated: 30+ days ago • Promoted
Telemedicine Physician
QuickMD • Progreso, TX, United States
Full-time
Last updated: 1 day ago • Promoted
Physical Therapist (PT)
Care Options for Kids Careers • WESLACO, TX, USA
Full-time
Last updated: 30+ days ago • Promoted
Physical Therapist (PT)
Care Options For Kids • Weslaco, TX, United States
Part-time
Last updated: 30+ days ago • Promoted
Pediatric Licensed Practical Nurse (LPN)
Care Options for Kids • Weslaco, TX, US
Full-time
Last updated: 30+ days ago • Promoted
Medical Experts
Quality Talent Group • Weslaco, Texas, United States
Full-time
Quick Apply
Last updated: 7 days ago
Physical Therapist / PT
Aegis Therapies • Mercedes, TX, United States
Full-time
Last updated: 30+ days ago • Promoted
Travel CT Technologist
HonorVet Technologies • Weslaco, TX, US
Full-time
Last updated: 30+ days ago • Promoted