Talent.com
Principal Manufacturing Technician
Principal Manufacturing TechnicianCurium Pharma • Maryland Heights, MO, United States
Principal Manufacturing Technician

Principal Manufacturing Technician

Curium Pharma • Maryland Heights, MO, United States
5 days ago
Job type
  • Full-time
Job description

Principal Manufacturing Technician

Date : Nov 13, 2025

Location :

Maryland Heights, MO, United States

About Curium

Curium is the world's largest nuclear medicine company with more than a century of industry experience. We develop, manufacture and distribute world-class radiopharmaceutical products to help patients around the globe. Our proven heritage combined with a pioneering approach are the hallmarks to deliver innovation, excellence and unparalleled service.

With manufacturing facilities across Europe and the United States, Curium delivers SPECT, PET and therapeutic radiopharmaceutical solutions for life-threatening diseases to over 14 million patients annually. The name 'Curium' honors the legacy of pioneering radioactive researchers Marie and Pierre Curie, after whom the radioactive element curium was named and emphasizes our focus on nuclear medicine. The tagline 'Life Forward' represents our commitment to securing a brighter future for all those we serve : An enhanced quality of care for our patients. A trusted partner to our customers. A supportive employer to our valued team.

Summary of Position

The Principal Manufacturing Technician - Cyclotron Operator is responsible for the safe and efficient operation of a particle accelerator (cyclotron) used in the production of radioisotopes for medical imaging, research, or industrial applications. This senior-level role includes oversight of daily operations, troubleshooting, routine maintenance, and mentoring junior staff. The operator ensures adherence to safety protocols and regulatory requirements governing radiation, equipment, and facility operations.

Schedule :

Tuesday - Friday (W1), Saturday - Monday (W2) (12-hour shifts)

Work Hours : 6 : 00 am to 6 : 00 pm, or 6 : 00 pm to 6 : 00 am

Ability to work overtime when necessary

Essential Functions

  • Must maintain operational compliance with US and international regulatory agencies and guidelines (i.e. FDA, EU, HC, TGA, PIC / S, ISO, USP, NRC, cGMP, etc.).
  • Ensure a safe and quality working environment.
  • Operate the cyclotron according to established protocols.
  • Monitor, adjust, and control beam parameters to optimize isotope yields and quality.
  • Perform routine start-up, shutdown, and preventative maintenance tasks.
  • Troubleshoot system failures and coordinate complex repairs with Cyclotron Specialist
  • Keep detailed logs of maintenance and operational activities.
  • Follow radiation safety procedures and use protective equipment.
  • Complete and maintain all required safety and operational documentation.
  • Record production data, radiation levels, and equipment performance metrics.
  • Generate reports on cyclotron output and operational incidents.
  • Provide oversight for cyclotron bombardments and technical training to junior operators
  • Perform other duties as assigned by area management (i.e. inventory management, spare parts, training, etc).
  • Willingness to work rotating shifts, weekends, and overtime, as necessary.

Requirements

  • Associate's degree in Electronics, Physics, Engineering, Nuclear Medicine Technology, or related field preferred.
  • Six or more years of relevant work experience required.
  • Equivalent technical training and experience will be considered.
  • Training in radiological safety and cyclotron operations preferred.
  • Ability to use a variety of general-purpose test equipment and bench test electronic system components.
  • Good mechanical inclination and proficiencies.
  • Good technical troubleshooting skills with and without schematics.
  • Experience in maintaining, troubleshooting, and repairing the following : solid state and vacuum tube based electronics, analog and digital circuits, logic circuits / PLCs, high power RF systems (high HF through low VHF ranges), high voltage DC power equipment, electro-mechanical systems, and vacuum systems (mechanical, cryogenic, and / or diffusion pumps) preferred.
  • Experience working around ionizing radiation sources preferred.
  • Experience working with pneumatics and hydraulics is preferred.
  • Ability to communicate equipment issues to Cyclotron Specialist.
  • Working Conditions :

  • Willingness to work in plant producing radioactive materials and requiring all employees to participate in safety programs designed to minimize potential and / or actual exposure levels.
  • Responsibilities include the ability to lift up to 70 pounds, kneeling, crouching, twisting the upper body, walking, bending, stooping, pushing, pulling, reaching, must be able to physically negotiate stairs and evacuation ladders with or without accommodation, wear and operate safety equipment, enter vessels, and inspect equipment.
  • Material handling devices (e.g., hand truck, fork truck, and conveyors) are used when possible, however, use of proper lifting and movement techniques is necessary to prevent injury.
  • Must be willing to wear a variety of Personal Protective Equipment (PPE) and hearing protection as needed.
  • May be required to sit or stand for long periods of 8+ hours a day while performing duties.
  • Must possess good hand-eye coordination; close attention to detail is required.
  • Must be able to work indoors and outdoors with exposure to mechanical / moving parts, hazards including corrosive, flammable and toxic material, dust, dirt, odors, and irritants.
  • Willingness to complete safety training within allotted timeframes, and work in a team-based environment.
  • Must be able to work outside of regular work hours, including off shift, weekend, and holiday work as business needs require.
  • Disclaimer

    The above statements are intended to describe the general nature and level of work being performed by employees assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of employees assigned to this position.

    Equal Opportunity Employer

    Curium is anequal opportunity employerand believes everyone deserves respect, dignity and equality.All applicants will be considered for employmentwithout attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

    Job Segment :

    Rad Tech, Medical Technologist, Facilities, Nuclear Engineering, Nuclear Physics, Healthcare, Operations, Science, Engineering

    Create a job alert for this search

    Manufacturing Technician • Maryland Heights, MO, United States

    Related jobs
    Production Tech 1-2nd Shift

    Production Tech 1-2nd Shift

    bioMérieux • Hazelwood, MO, United States
    Full-time
    The Production Technician I position is responsible for the operation of high speed equipment used in the production and packaging of VITEK 2 cards in a cGMP compliant manner.The position may perfo...Show more
    Last updated: 3 hours ago • Promoted • New!
    Manufacturing Engineer II

    Manufacturing Engineer II

    Donaldson Company • Chesterfield, MO, United States
    Full-time
    Donaldson is committed to solving the world's most complex filtration challenges.As an established technology and innovation leader, we are continuously evolving to meet the filtration needs of our...Show more
    Last updated: 29 days ago • Promoted
    Printer Technician Team Lead

    Printer Technician Team Lead

    Sage Solutions Group • St. Louis, MO, US
    Full-time
    Quick Apply
    Printer Technician Team Lead Location : .Fenton, Missouri (On-site) Compensation : $60,000 - $65,000 annually Imagine working in a place where your manager truly believes in your personal and pr...Show more
    Last updated: 30+ days ago
    Proprietary Program Systems Engineering Technician (Experienced or Lead)

    Proprietary Program Systems Engineering Technician (Experienced or Lead)

    Boeing • Hazelwood, MO, US
    Full-time +1
    At Boeing, we innovate and collaborate to make the world a better place.We’re committed to fostering an environment for every teammate that’s welcoming, respectful and inclusive, with great opportu...Show more
    Last updated: less than 1 hour ago • Promoted • New!
    Blood Component Manufacturing Technician

    Blood Component Manufacturing Technician

    American Red Cross • St. Louis, MO, United States
    Full-time
    Please use Google Chrome or Mozilla Firefox when accessing Candidate Home.By joining the American Red Cross you will touch millions of lives every year and experience the greatness of the human spi...Show more
    Last updated: 30+ days ago • Promoted
    Maintenance Technician

    Maintenance Technician

    Avantor • St. Louis, MO, United States
    Full-time
    Avantor is looking for a dedicated and experienced.The Maintenance Technician will conduct general maintenance activities primarily on machinery and related equipment. maintain repair and maintenan...Show more
    Last updated: 18 days ago • Promoted
    Sr. Downstream Processing Technician

    Sr. Downstream Processing Technician

    Actalent • St Louis, MO, United States
    Full-time
    Downstream Processing Technician.The Downstream Processing Technician will support the manufacture of commercial and clinical biologics by performing operations in accordance with Current Good Manu...Show more
    Last updated: 18 days ago • Promoted
    Production Tech 1-2nd Shift

    Production Tech 1-2nd Shift

    Biomerieux • Hazelwood, MO, United States
    Full-time
    The Production Technician I position is responsible for the operation of high speed equipment used in the production and packaging of VITEK 2 cards in a cGMP compliant manner.The position may perfo...Show more
    Last updated: 3 hours ago • Promoted • New!
    Proprietary Program Systems Engineering Technician (Experienced or Lead)

    Proprietary Program Systems Engineering Technician (Experienced or Lead)

    BOEING • Hazelwood, MO, US
    Full-time +1
    At Boeing, we innovate and collaborate to make the world a better place.We’re committed to fostering an environment for every teammate that’s welcoming, respectful and inclusive, with great opportu...Show more
    Last updated: 4 days ago • Promoted
    Process Technician

    Process Technician

    C.L. Smith Company • St. Louis, MO, USA
    Full-time
    Quick Apply
    Become a part of the new LBM culture.We are now partnered with Novvia Group! Fun family work environment.Paid vacation and personal time, 8 company holidays, 401(k), health insurance (medical, dent...Show more
    Last updated: 30+ days ago
    Maintenance Technician - Aerospace Manufacturing

    Maintenance Technician - Aerospace Manufacturing

    Seyer Industries Inc. • St Peters, MO, USA
    Full-time
    Quick Apply
    Machine Maintenance Technician!.Year-round climate-controlled work environment.Start accruing vacation from day one! Accrued each pay period, you will. Anniversary paid day off awarded each year.Tha...Show more
    Last updated: 30+ days ago
    Manufacturing Lead

    Manufacturing Lead

    Winco Window Company • University City, Missouri, United States
    Full-time
    Quick Apply
    Winco Windows is currently looking to hire a full-time Manufacturing Lead or Supervisor in Training.Skills desired for an applicant : . Able to work from 7 : 00 am to 3 : 30 pm for the day shift or 3 : 30 p...Show more
    Last updated: 30+ days ago
    Maintenance Technician

    Maintenance Technician

    Wieland Group • East Alton, IL, United States
    Full-time
    Wieland - Creating Value for Generations!.Wieland is a global leader in copper and copper alloy manufacturing, processing, and distribution. We provide a large product and service portfolio includin...Show more
    Last updated: 30+ days ago • Promoted
    Maintenance Technician

    Maintenance Technician

    Recruiting Module • St. Louis, MO, US
    Full-time
    Assemble, calibrate, and repair valve actuators and instruments.Diagnose and resolve equipment issues both in-shop and on-site. Conduct steam surveys, perform Hot-Water heater cleanouts and support ...Show more
    Last updated: 2 days ago • Promoted
    Printer Technician

    Printer Technician

    Revolution Technologies • St Louis, MO, US
    Full-time
    Onsite Service Technician supporting large medical facility.Delivery and installation of printer supplies, maintains, repairs equipment. Conducts technical analysis of product implementations, to pr...Show more
    Last updated: 7 hours ago • Promoted • New!
    Operations Manufacturing Leader

    Operations Manufacturing Leader

    Watlow • St. Louis, MO, United States
    Full-time
    Watlow is a global technology and manufacturing leader who provides world class engineering expertise through innovative thermal products and systems, enabling our customers to thrive.We are making...Show more
    Last updated: 30+ days ago • Promoted
    Maintenance Technician, 3rd Shift

    Maintenance Technician, 3rd Shift

    C.L. Smith Company • St. Louis, MO, USA
    Full-time
    Quick Apply
    Become a part of the new LBM culture.We are now partnered with Novvia Group! Fun family work environment.Paid vacation and personal time, 8 company holidays, 401(k), health insurance (medical, dent...Show more
    Last updated: 30+ days ago
    Production Technicians - 2nd and 3rd Shift Opportunities

    Production Technicians - 2nd and 3rd Shift Opportunities

    Woodbridge Corporation • St Peters, MO, USA
    Full-time
    Quick Apply
    Woodbridge is a privately-owned company offering innovative material technologies for applications in automotive, commercial, recreational, packaging, healthcare and building products.In addition t...Show more
    Last updated: 30+ days ago