Lead, Research Data Scientist Cancer, Dr. Cullen lab

Overview

Will play a vital role in creating managing and integrating clinical and research data infrastructure for the Cancer Prevention and Control Program (CPC). They will ensure data harmonization and compliance with industry standards. This position will oversee the development and optimization of data pipelines statistical data analysis facilitate research collaboration with other cancer centers and promote data quality initiatives. The ideal candidate will bridge the gap between technical data requirements and clinical research needs supporting CPC and its mission to advance cancer research through high-quality real-world data.

• Design implement and maintain a state-of-the-art data management infrastructure that includes robust DataMart from multiple novel sources reflecting medical social genomic and environmental drivers of health consistent with the departmental mission.
• Engage in strategic negotiations and collaborations with key data providers including institutional EMR teams the Texas Cancer Registry and other state and local agencies to secure access to data critical to understanding the medical and socioecological contexts of health in patients with cancer. Liaise with multidisciplinary teams to ensure seamless data flow integration and alignment with project objectives.
• Oversee strategic guidance on data elements methods and models required for clinical and research objectives and facilitate the identification and extraction of these elements from the EHR and data warehouse systems.
• Oversee data collection and harmonization processes ensuring compliance with applicable industry data standards (e.g. FHIR HL7 NAACCR).
• Collaboratively develop and deploy quality assurance (QA) and quality control (QC) measures to maintain data integrity and reliability.
• Apply statistical and epidemiological methods to analyze data on health outcomes and survival in patients with cancer. Develop and adhere to statistical analysis plans (SAP) prepare research presentations and draft results for peer-reviewed publications.
• Monitor emerging trends and developments in real-world clinico-omic data informatics and provide strategic recommendations on technologies and processes to optimize and advance the CPC data ecosystem.
• Prepare and present data insights integration strategies and progress reports to internal and external stakeholders.
• Enhance scientific discovery by contributing to hypothesis generation cohort identification publications presentations and proposals that advance CPC program goals.
• Establish a streamlined process for research approval that includes developing an umbrella IRB protocol and standardized data-use agreements for the novel data warehouses to facilitate quicker start times for research projects.
• Manage an expanding team with varied expertise within the Clinical Informatics and Data Sciences Group. Train mentor and supervise staff on data workflow processes good practices and standards.
• Strong understanding of data interoperability standards (e.g. FHIR HL7 OMOP CDISC NAACCR).
• Knowledge of regulatory frameworks such as HIPAA GDPR and GCP.
• Familiarity with cancer genomics repositories and / or cancer registries is highly desirable.

Technical Proficiency :

Houston Methodist Standard

PATIENT AGE GROUP(S) AND POPULATION(S) SERVED

Refer to departmental Scope of Service and Provision of Care plans as applicable for description of primary age groups and populations served by this job for the respective HM entity.

HOUSTON METHODIST EXPERIENCE EXPECTATIONS

INTEGRITY : We are honest and ethical in all we say and do.

Responsibilities

PEOPLE ESSENTIAL FUNCTIONS

SERVICE ESSENTIAL FUNCTIONS

QUALITY / SAFETY ESSENTIAL FUNCTIONS

FINANCE ESSENTIAL FUNCTIONS

GROWTH / INNOVATION ESSENTIAL FUNCTIONS

This job description is not intended to be all-inclusive; the employee will also perform other reasonably related business / job duties as assigned. Houston Methodist reserves the right to revise job duties and responsibilities as the need arises.

Qualifications

EDUCATION

WORK EXPERIENCE

License / Certification

LICENSES AND CERTIFICATIONS - REQUIRED

LICENSES AND CERTIFICATIONS - PREFERRED

KSA / Supplemental Data

KNOWLEDGE SKILLS AND ABILITIES

SUPPLEMENTAL REQUIREMENTS

WORK ATTIRE

ON-CALL

TRAVEL

Company Profile

Houston Methodist Research Institute was formed in 2004 to rapidly and efficiently translate discoveries made in the laboratory and the clinic into new diagnostics therapies and treatments. The research institute was created to provide the infrastructure and support for these endeavors and to house the technology and resources needed to make innovative breakthroughs in important areas of human disease. A 540000 square foot building dedicated to research the research institute houses over 1500 staff and trainees 284 principal investigators and has more than 570 ongoing clinical trials.

Key Skills

Laboratory Experience,Machine Learning,Python,AI,Bioinformatics,C / C++,R,Biochemistry,Research Experience,Natural Language Processing,Deep Learning,Molecular Biology

Employment Type : Full-Time

Experience : years

Vacancy : 1