Lab Operations Manager

Job Description

Job Description

Why Join Us?

Parabilis Medicines, Inc is a biopharmaceutical company pioneering the discovery and development of Helicon™ peptide therapeutics; these ultra diverse alpha-helical peptides are capable of efficient cell entry and modulation of both protein-protein and protein-DNA interactions. Through Helicon therapeutics, Parabilis is poised to revolutionize the medical possibilities for patients by precisely drugging intracellular targets long understood to be significant drivers of disease but never before drugged due to the limitations of existing drug modalities to act within the cell. FOG-001, the company's first-in-class TCF-blocking β-catenin inhibitor, is being evaluated in a Phase 1 / 2 study for patients with advanced solid tumors, including desmoid tumors and colorectal cancer. Parabilis is fully leveraging the unprecedented potential Helicons present by deploying proprietary, custom-built machine learning and computational methods as part of its discovery and development process. Parabilis Medicines has raised more than $500 million to date from leading life sciences investors. Parabilis is headquartered in Cambridge, Mass.

What's the opportunity?

The Lab Operations Manager will focus on strategic procurement, inventory systems, vendor partnerships, safety protocols, and regulatory compliance. Reporting to the AD, Research Operations, this individual will serve as a critical operational leader and bridge between scientific teams, operations, finance, and suppliers—ensuring the lab environment is resourced, compliant, and optimized for cutting-edge research and programs.

The ideal candidate brings a blend of scientific understanding and operational expertise, with a strong track record in driving continuous improvement, developing standard operating procedures (SOPs), and leveraging data for strategic decisions.

Procurement & Vendor Management

• Manage end-to-end procurement of reagents, consumables, chemicals, equipment, and specialty supplies.
• Evaluate and onboard new vendors, ensuring scientific compatibility and compliance with internal policies. Negotiate vendor contracts to optimize cost, lead time, and service quality. Collaborate with Finance and Procurement teams to maintain budget alignment and approval workflows.
• Monitor and report on vendor KPIs (e.g., delivery timeliness, quality issues, pricing trends), and drive corrective actions where needed.
• Coordinate customs, import / export logistics, and cold-chain shipments for regulated or overseas materials.

Inventory & Materials Management

Safety & Compliance

Additional Projects and Duties

What you'll need to be successful :

Core Values

Parabilis Medicines is a team of passionate pioneers who are trailblazing the future of precision medicine with the aim of making a meaningful difference in the lives of patients. The company is committed to promoting an inspiring and flourishing working environment for all employees across the business, in all departments, and driving innovation for patient benefit.

The base salary range for this position is $107,000 - $140,000 per year, depending on experience, qualifications, and internal practices. Parabilis's total compensation package also includes an annual target bonus, equity, and a comprehensive suite of competitive benefits designed to support our employees' overall well-being.

As an equal opportunity employer, Parabilis Medicines values an inclusive workplace and welcomes applicants of all backgrounds and experiences. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law.

30 Acorn Park Drive | Cambridge, MA 02140 | www.parabilismed.com