Global Commercial Director T2D, CVRM

At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We’re focused on the potential of science to address the unmet needs of patients around the world. We commit to those areas where we think we can really change the course of medicine.

Within our BBU CVRM franchise, we’ve established a new commercial area focused on Weight Management and Type 2 Diabetes (T2D). Our ambition is to deliver a portfolio of simple, scalable, and sustainable solutions that improve health and wellbeing, reduce cardiometabolic risk and protect organs for people living with diabetes, overweight, and / or obesity.

To achieve this, we’re seeking an experienced commercial leader to shape the launch strategy for one of our lead assets in T2D and related cardiometabolic conditions. This is a pivotal pre-launch role that defines how we bring the science to market and prepare the organization for launch success.

The role reports to the Global Commercial Head Weight Management

Key Responsibilities

Lead development of a global go-to-market (GTM) strategy — including market segmentation, positioning, target audiences, and launch sequencing.

Translate strategic objectives into an actionable global pre-launch roadmap, defining the value proposition, brand narrative, and engagement approach.

Partner with regional and country commercial leaders to ensure global alignment and adaptability to local market realities.

Create and socialize a clear brand strategy that balances scientific differentiation with emotional resonance across key stakeholders (HCPs, payers, patients, advocacy).

Lead deep analysis of market dynamics, competitive environment, and evolving treatment paradigms to anticipate opportunities and risks.

Partner with Insights, Analytics & Forecasting teams to generate actionable market and customer insights that inform TPP design, clinical plans, and launch assumptions.

Develop and execute market-shaping initiatives — including awareness, disease-education, and early-access strategies — to create readiness ahead of launch.

Build external validation loops through advisory boards, stakeholder mapping, and co-creation with key opinion leaders and advocacy groups.

Partner closely with R&D, Clinical, Regulatory, Medical Affairs, Pricing & Market Access, and Global Product Teams to ensure the commercial voice is embedded early in development.

Align global functions around clear pre-launch milestones (e.g., TPP validation, pricing strategy, access readiness, global narrative, and launch framework).

Define and track KPIs to measure organizational readiness and strategic progress toward launch.

Collaborate with regional / country teams to ensure knowledge transfer, toolkit development, and capability building for first-wave markets.

Oversee creation of core global brand assets and messaging frameworks to ensure consistency across markets and channels.

Manage relationships with creative and strategic agencies, consultants, and other third-party partners to develop pre-launch materials and campaigns.

Lead development of the brand identity system — naming, tone of voice, and creative direction — in alignment with AstraZeneca standards and scientific integrity.

Serve as a key member of the Global Commercial Leadership Team, ensuring transparency of strategy, timelines, and investment decisions.

Present GTM recommendations, forecasts, and business cases to governance boards and senior leadership.

Foster strong collaboration across functions and geographies; champion a culture of curiosity, accountability, and evidence-based decision making.

Essential Skills / Experience

Bachelor’s degree required; advanced degree (MBA, PhD, or MSc) preferred.

10+ years experience in pharmaceutical commercial strategy or marketing, ideally in pre-launch or early launch settings.

Relevant experience in TA : cardiometabolic, obesity, or T2D

Strong track record in developing and executing go-to-market or brand strategies that integrate insight generation, forecasting, and positioning.

Proven ability to collaborate across scientific, regulatory, and commercial interfaces to drive alignment.

Excellent analytical, strategic, and communication skills; comfortable influencing at senior levels in a matrixed environment.

Self-starter with high energy, intellectual curiosity, and the ability to lead through ambiguity

Desirable Skills

Experience in US or other large market

Previous experience in global role

Direct experience in market shaping, disease education, or pre-launch activation.

Strong working knowledge of pricing, reimbursement, and access strategy.

Familiarity with digital ecosystem development and omnichannel stakeholder engagement.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

AstraZeneca offers an environment where diversity is our strength, reflecting the variety of patients we serve. Here, you'll find a place for continuous learning, exchanging knowledge, and building best practices to grow your career. With a fusion of support, trust, and agility, you'll be encouraged to bring your whole self to work and embrace all the investment, feedback, and ample opportunities on offer. It's an exciting time for our team as we redefine the future of healthcare.

Ready to jump in and be part of something extraordinary? Apply now and take the next step in your career journey with AstraZeneca!

The annual base pay for this position ranges from $229,303 to $343,955. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles),to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department / team performance, and market factors.

Date Posted

06-Nov-2025

Closing Date

19-Nov-2025

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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