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Software Architect (Clinical Trials Platform)
Software Architect (Clinical Trials Platform)Azra AI • Nashville, TN, US
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Software Architect (Clinical Trials Platform)

Software Architect (Clinical Trials Platform)

Azra AI • Nashville, TN, US
4 days ago
Job type
  • Full-time
Job description

About the Role

We are seeking a Software Architect to design, develop, and lead the architecture of a modern clinical trials platform. This system will integrate directly with EMRs / EHRs, receive and normalize clinical data from multiple sources (HL7, FHIR, CCD, and APIs), standardize coded clinical information (ICD-10, SNOMED, LOINC), and support automated downstream decision and workflow engines.

You will define the architectural direction for secure integrations, ingestion pipelines, clinical data models, and event-driven processing. This role is both highly strategic and hands-on, partnering closely with engineering, data, and clinical informatics teams to build a scalable, compliant platform used across diverse healthcare environments.

Salary Range : $150-$180k

Key Responsibilities

System Architecture & Platform Design

  • Architect end-to-end systems for ingesting, normalizing, and operationalizing clinical data.
  • Create scalable, fault-tolerant service architectures using microservices, event-driven patterns, or modular domain-driven design.
  • Produce architectural diagrams, integration patterns, data models, and API standards.
  • Define platform-wide guidelines for service decomposition, state management, data contracts, and code quality.

EMR Integrations & Clinical Data Ingestion

  • Architect and implement secure, compliant EMR / EHR integrations using :
  • HL7 v2 (ADT, ORU, ORM, SIU, custom Z-segments)
  • FHIR R4 resources and RESTful APIs
  • CCD / C-CDA documents
  • Vendor interfaces (Epic, Cerner, Athenahealth, Meditech, etc.)
  • Build ingestion pipelines for pathology, radiology, diagnostic data, labs, medications, problems, encounters, and other clinical artifacts.
  • Normalize and standardize data using clinical coding systems, including :
  • ICD-10
  • SNOMED CT
  • LOINC
  • RxNorm
  • Implement clinical data validation, deduplication, reconciliation, and identity matching.
  • Interoperability & Integration Framework

  • Design reusable interoperability frameworks for onboarding new health systems.
  • Establish secure communication channels (VPN, SFTP, APIs, FHIR Subscriptions, eventing).
  • Ensure alignment with HIPAA, SOC2, HITRUST, and enterprise privacy / security policies.
  • Define repeatable onboarding patterns for rapid integration with hospital IT teams.
  • Application & Backend Development

  • Build core backend services using modern application frameworks (Java / Kotlin, Go, Python, etc.).
  • Develop APIs and event-driven microservices for data ingestion, normalization, storage, and downstream workflows.
  • Optimize system performance with caching, concurrency, streaming, and resilience patterns.
  • Provide hands-on engineering, code review, and mentorship to the development team.
  • Data Architecture & Storage Design

  • Define operational schemas for patient demographics, encounters, clinical observations, diagnostic results, and provider data.
  • Partner with data engineering teams on schema design, warehouse patterns, and lineage.
  • Create separation layers between real-time ingestion, normalized stores, and analytical datasets.
  • Ensure data integrity, primary / foreign key mappings, ICD / SNOMED / LOINC code handling, and longitudinal patient histories.
  • Quality, Security, & Compliance

  • Implement architectural patterns for encrypted PHI handling, IAM policies, access controls, and audit trails.
  • Establish automated testing strategies : contract tests, schema tests, integration tests, and workflow validation.
  • Ensure the platform meets healthcare compliance and interoperability expectations across diverse clients.
  • Required Qualifications

    Experience in Healthcare Application Architecture

  • 5+ years as a software architect or senior engineer designing distributed platforms.
  • Demonstrated experience with EMR / EHR integrations (HL7, FHIR, CCD, or vendor APIs).
  • Understanding of clinical data structures, patient-centric workflows, and healthcare interoperability standards.
  • Technical Expertise

  • Proficiency in one or more backend languages : Java / Kotlin, Python, Go, etc.
  • Experience with event-driven systems (Pub / Sub, Kafka, SNS / SQS, or similar).
  • Strong understanding of cloud platforms (GCP preferred; AWS or Azure acceptable).
  • Experience with operational and NoSQL databases for structured and semi-structured healthcare data.
  • Interoperability & Clinical Data Knowledge

  • Hands-on experience with HL7 v2 message structures and FHIR resources
  • Understanding of coded clinical systems, including ICD-10, SNOMED CT, LOINC, and RxNorm.
  • Architecture & Development Skills

  • Deep understanding of system design, API architecture, and microservices.
  • Ability to build scalable, high-availability systems.
  • Strong foundation in CI / CD, DevOps practices, infrastructure-as-code, and observability.
  • Bonus Skills (Preferred but Not Required)

  • Experience with workflow engines
  • Familiarity with AI / ML models for clinical text processing or structured data interpretation.
  • Experience with GCP analytics tools (BigQuery, Dataflow, Dataform / dbt / Sqlmesh).
  • Background in pathology, radiology, or structured and unstructured clinical document processing.
  • Experience building healthcare SaaS platforms.
  • Why Join Us?

  • Architect a modern clinical data platform used across large healthcare systems.
  • Work at the intersection of interoperability, cloud architecture, and real-world clinical data.
  • Collaborate with engineering, clinical informatics, and data teams to build mission-critical healthcare technology.
  • Work with modern, cloud-native tools in a fully remote environment with high autonomy and ownership.
  • Fully remote opportunity with a high-impact role.
  • Create a job alert for this search

    Clinical Trial • Nashville, TN, US

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