Associate Scientist II

Associate Scientist II

The experienced Research Associate Scientist II, with a background in in vitro screening, will be part of our dynamic, fast-paced and interdisciplinary lead development team. Our mission is to advance novel RNAi therapeutic programs from target discovery through lead candidate selection. The Associate Scientist II will be technically skilled in molecular and / or cell biology, and bring a rigorous, analytical approach to research.

Key Responsibilities

• Perform cell culture (iPSCs, primary cells, immortalized cell lines) to support the research needs of the group and high-throughput screening of siRNAs using qPCR and a variety of cell-based assays
• Execute day to day operations for RNASeq sample preparation, including : library preparation, QC and sequencing. Maintain sample tracking & records.
• Conduct assays that support in vivo studies (e.g. qPCR, ELISA) for the quantitative analysis of biomarkers or siRNA activity
• Support lab maintenance including equipment operation & maintenance , reagent inventory and reagent preparation
• Troubleshoot technical problems and participate in the continuing development and optimization of existing and new protocols.
• Utilize instrumentation and robotics to aid in high throughput (384-well) screening.
• Adapts well to the changing platform needs, in workflow, projects and other tasks as required by the platform.

Qualifications