PK/PD Modeling / Pharmacometrics LeadMercor • Longview, Texas, US
No longer accepting applications
PK / PD Modeling / Pharmacometrics Lead
Mercor • Longview, Texas, US
1 day ago
Job type
- Part-time
- Remote
Job descriptionWho we’re looking for Deep hands-on experience in PK, PD, exposure–response modeling , and ideally population PK or QSP . - Expert at model fitting, sensitivity analysis, and identifying non-plausible parameter spaces. - Can evaluate the validity of dose–exposure predictions and detect high-risk extrapolations. - Comfortable designing model evaluation rubrics that distinguish between acceptable vs. non-credible outputs. - Able to articulate how quantitative checks should complement narrative decision logic. Nice-to-have : Experience supporting translational or clinical pharmacology leads in dose justification. - Familiarity with integrating nonclinical PK / PD data (2-species GLP → human FIH extrapolation). ### Experience level ~8–12 years of quantitative pharmacology experience in pharma, CROs, or modeling consultancies . - Strong portfolio in population PK / PD exposure–response , and parameter estimation using NONMEM, Monolix, or equivalent tools. - Demonstrated ability to interpret model results for decision-making, not just fit data. - Can create fit-for-purpose models and critique model structures or assumptions under uncertainty. ### Expectations Design and refine micro-evaluations for PK / PD performance (curve fits, parameter checks, error taxonomies). - Encode quantitative sanity checks into model rubrics for automated evaluation. - Define failure conditions (e.g., unsafe extrapolation, poor coverage curves, invalid assumptions). Inputs we give : PK / PD datasets, tox summaries, and performance prompts (e.g., “fit exposure–response curves, interpret safety margins”). - Example model outputs from automated systems. Expected outputs : Quantitative Rubrics : clear thresholds for acceptable parameter fits, coverage curve quality, and model integrity checks. - Golden Fit Examples : representative “ideal” PK / PD model outputs and visualizations for calibration. - Error Taxonomy : structured list of typical modeling or fitting errors, with root-cause annotations. - Meta-Layer Commentary : short note per rubric capturing how expert modelers recognize implausible or unsafe fits beyond numeric error values. ### Engagement Model & Compensation Contract / part-time , remote, outcome-based deliverables.
This person complements the client’s “Translational / Clinical Pharmacology Decision-Maker” team by grounding dose selection and exposure–response analysis in
- quantitative structure and parameter plausibility
###
Create a job alert for this search
Modeling • Longview, Texas, US
Related jobs
DocCafe has an immediate opening for the following position : Physician - Hematology / Oncology in Longview, Texas.DocCafe is the premier physician and advanced practice job board to help you advance ...Show more
DocCafe has an immediate opening for the following position : Physician - Emergency Medicine in Texas.DocCafe is the premier physician and advanced practice job board to help you advance your health...Show more
AlliedTravelCareers is working with Host Healthcare to find a qualified Physical Therapist (PT) in Longview, Texas, 75605! Pay Information $1,524 to $...Show more
All pharmacists fill orders for drugs, monitor patient drug therapies and provide drug information.Pharmacists provide pharmacy services with compassion, excellence, and efficiency.Meets expectatio...Show more
Are you a compassionate and dependable individual who is looking for a career that means something? Do you have a passion for serving others and a desire to know you are making a difference? If so,...Show more
We are hiring for a PRN Physical Therapist in the Longview area.At CHRISTUS Good Shepherd HomeCare, a part of LHC Group, we embrace a culture of caring, belonging, and trust and enjoy the meaningfu...Show more
We are hiring for a PRN Physical Therapist in the Longview area.At CHRISTUS Good Shepherd HomeCare, a part of LHC Group, we embrace a culture of caring, belonging, and trust and enjoy the meaningfu...Show more
LocumJobsNetwork is working with Weatherby Healthcare to find a qualified Pulmonology MD in Longview, Texas, 75605!.Interested? Give Weatherby a call today and speak with one of our specialty-speci...Show more
Endocrinology physician employment in Texas : CompHealth exists to make the locums process easier.Not only will we search for jobs that fit your interests, we'll be here to handle all the details l...Show more
PeaceHealth Medical Group is seeking a full-time Dermatologist in beautiful Longview, Washington.The PeaceHealth Dermatology Clinic is a thriving practice that focuses on the diagnosis and manageme...Show more LocumJobsNetwork is working with CompHealth to find a qualified Endocrinology MD in Longview, Texas, 75601!.CompHealth exists to make the locums process easier.
Not only will we search for jobs that...Show more 
Outpatient Internal Medicine PA position joining well established 73 year old practice with (3) Internal Medicine and (4) IM APP providers with a 4 day work week in a desirable family oriented SW W...Show more
LocumJobsOnline is working with CompHealth to find a qualified Endocrinology MD in Longview, Texas, 75601!About The PositionCompHealth exists to make the locums process easier.Not only will we sear...Show more
LocumJobsOnline is working with CompHealth to find a qualified Cardiology MD in Longview, Texas, 75601!.When it comes to finding the perfect locums assignment, sometimes it is all about who you kno...Show more
Certifications : FM, EM, IM / Peds.Are you an experienced and compassionate Emergency Medicine physician seeking an exciting locum tenens opportunity in Longview, TX? Look no further! Our esteemed me...Show more
Our client is a leading force in advancing safer, smarter AI technology.Their work has been featured in.They’ve built a global community of expert contributors and have already paid out more ...Show more LocumJobsNetwork is working with CompHealth to find a qualified Cardiology MD in Longview, Texas, 75601!.When it comes to finding the perfect locums assignment, sometimes it is all about who you kn...Show more 
CompHealth exists to make the locums process easier.Not only will we search for jobs that fit your interests, we'll be here to handle all the details like credentialing, housing, travel arrangement...Show more
Hematology / Oncology Physician - Competitive Salary (Longview)
DocCafe • Longview, TX, US
Part-time
Last updated: 1 day ago • Promoted
Emergency Medicine Physician - Competitive Salary (Longview)
DocCafe • Longview, TX, United States
Full-time
Last updated: 18 days ago • Promoted
Travel Physical Therapist (PT) - $1,547 to $1,696 per week in Longview, TX
AlliedTravelCareers • Longview, TX, USA
Full-time
Last updated: 30+ days ago • Promoted
Clinical Pharmacist I - Longview Pharmacy - PRN (Longview)
Christus Health • Longview, TX, US
Part-time
Last updated: 16 days ago • Promoted
Med Tech
Sagora Senior Living • Longview, TX, United States
Full-time
Last updated: 21 hours ago • Promoted • New!
Physical Therapist, PT PRN
CHRISTUS Good Shepherd • Longview, TX, US
Full-time
Last updated: 30+ days ago • Promoted
Physical Therapist, PT PRN
LHC Group • Longview, TX, United States
Full-time
Last updated: 30+ days ago • Promoted
Locum Physician (MD / DO) - Pulmonology in Longview, TX
LocumJobsNetwork • Longview, TX, US
Full-time
Last updated: 30+ days ago • Promoted
Endocrinology
CompHealth • Longview, Texas, US
Full-time
Last updated: 14 hours ago • Promoted • New!
Dermatologist
PeaceHealth • Longview, US
Full-time
Last updated: 30+ days ago • Promoted
Locum Physician (MD / DO) - Endocrinology in Longview, TX
LocumJobsNetwork • Longview, TX, US
Full-time +1
Last updated: 17 hours ago • Promoted • New!
Internal Medicine PA
Donohue and Associates • Longview, US
Full-time
Last updated: 30+ days ago • Promoted
Locum Physician (MD / DO) - Endocrinology in Longview, TX
LocumJobsOnline • Longview, Texas, United States
Permanent
Last updated: less than 1 hour ago • Promoted • New!
Locum Physician (MD / DO) - Cardiology - General / Other in Longview, TX
LocumJobsOnline • Longview, TX, US
Full-time +1
Last updated: 30+ days ago • Promoted
Emergency Medicine Physician -Longview, TX- $250 / hr
She Recruits, LLC • Longview, TX, United States
Full-time
Last updated: 30+ days ago • Promoted
Engineer
Quality Talent Group • Longview, Texas, United States
Full-time
Quick Apply
Last updated: 8 days ago
Locum Physician (MD / DO) - Cardiology - General / Other in Longview, TX
LocumJobsNetwork • Longview, TX, US
Full-time +1
Last updated: 30+ days ago • Promoted
Locum Physician (MD / DO) - Endocrinology in Longview, TX
CompHealth • Longview, TX, United States
Full-time
Last updated: 5 hours ago • Promoted • New!