Remote PK/PD Module expert: Translational / Clinical Pharmacology Decision-Maker - AI Trainer ($175-$250 per hour)Mercor • Shakopee, Minnesota, US
Remote PK / PD Module expert : Translational / Clinical Pharmacology Decision-Maker - AI Trainer ($175-$250 per hour)
Mercor • Shakopee, Minnesota, US
5 days ago
Job type
- Full-time
- Remote
Job descriptionWho we’re looking for Has owned FIH starting dose, SAD / MAD design, and Phase 2 dose selection for multiple assets. - Participated in governance or review boards, defending dose / exposure rationale in front of senior leadership or regulators. - Demonstrates ability to balance nonclinical → clinical translation : tox, PK, PD, potency, and MoA. - Can articulate the real decision calculus behind dose selection (safety, pharmacology, speed-to-proof). - Capable of turning narrative judgment into explicit decision rules and rubrics for AI training and evaluation. ### Experience level ~10+ years in major biopharma or biotech (e.g., Lilly, Roche, AbbVie, Amgen, Novartis, GSK, Regeneron, Vertex, Incyte, Gilead) or in specialized translational pharmacology consulting. - Has personally led FIH dose and / or SAD / MAD escalation for ≥2–3 assets. - Proven governance experience : IND sign-off, dose justification memos, exposure–response presentations. - CV or track record includes statements like _“led clinical pharmacology strategy and FIH dose selection”_ or _“accountable for exposure–response in Phase 1 / 2.”_ - Avoid pure modeling profiles; the ideal expert has decision accountability , not just analytical skill. ### Expectations Write “golden” FIH dose rationales and escalation strategies for representative programs. - Encode the decision heuristics and trade-offs used by senior translational leaders into structured guidance and rubrics. - Surface unwritten decision rules — when and why experienced teams override model-based recommendations. Inputs given : Representative drug programs or data packets (GLP tox summaries, PK / PD tables, potency & MoA context). - Target prompts for translational decision-making (e.g., _“Recommend FIH dose and escalation strategy given these data”_). Expected outputs : Golden Decision Memos : exemplar dose justification memos that reflect the level of reasoning and format expected from top-tier translational pharmacologists. - Decision Rubrics : scoring guides capturing acceptable vs. unsafe dose rationales, missed edge cases, or failure modes. - Meta-Layer Commentary : short narrative explaining unspoken heuristics — how senior teams weigh risk tolerance, potency data, or tox uncertainty.
The client is seeking an external expert who brings a
- decision-maker’s mindset
- — someone who has personally driven translational pharmacology choices under governance and uncertainty.
###
Create a job alert for this search
Module Translational • Shakopee, Minnesota, US
Related jobs
Join Our Part-Time Research Studies Today!.Are you eager to earn extra income from the comfort of your home? We are looking for motivated individuals to participate in paid research studies includi...Show more UK / Canada / Europe / Singapore / Dubai / Australia-based • •Investment Banking or Private Equity Experts • • for a research project with a leading foundational model AI lab.
You are a good fit if you : - Have •...Show more 
Receive a $5 welcome bonus when you complete your first offer!Make money in your spare time by completing online tasks : .
Take paid surveys (5-15 minutes each).Test new mobile games and apps.Share yo...Show more
Home Care Physical Therapist -.Enjoy independence, autonomy, and flexibility in the field to visit patients one on one in their home environment.
Hours : Full-time - Days, Monday - Friday ...Show more
Candidates within commuting distance of a Wolters Kluwer office will be considered for hybrid employment.Candidates not within commuting distances will be considered for remote employment.FTE commi...Show more Join Our Part-Time Research Studies Today!.Are you eager to earn extra income from the comfort of your home? We are looking for motivated individuals to participate in paid research studies includi...Show more 
We are urgently looking for people interested in taking online surveys for Fortune 500 brands.If you are a self-starter, looking for flexible hours throughout the week, this may be for you! Earn up...Show more
Top Technical Skills & Requirements.Programming Expertise : 3+ years of hands-on experience with C# and Python, including building scalable applications and integrating ML models.API Development & M...Show more
UK / Canada / Europe / Singapore / Dubai / Australia-based • •Investment Banking or Private Equity Experts • • for a research project with a leading foundational model AI lab.
You are a good fit if you : - Have •...Show more
Focus Group We are a gambling technology company looking for individuals to join our focus group on an ongoing, part-time basis.
You will earn $800 to $1,200 for about 20 hours of participation, wit...Show more Join Our Part-Time Research Studies Today!.Are you eager to earn extra income from the comfort of your home? We are looking for motivated individuals to participate in paid research studies includi...Show more UK / Canada / Europe / Singapore / Dubai / Australia-based • •Investment Banking or Private Equity Experts • • for a research project with a leading foundational model AI lab.
You are a good fit if you : - Have •...Show more UK / Canada / Europe / Singapore / Dubai / Australia-based • •Investment Banking or Private Equity Experts • • for a research project with a leading foundational model AI lab.
You are a good fit if you : - Have •...Show more Candidates within commuting distance of a Wolters Kluwer office will be considered for hybrid employment.Candidates not within commuting distances will be considered for remote employment.FTE commi...Show more 
We are looking for a finance professional to join our team to train AI models.You will measure the progress of these AI chatbots, evaluate their logic, and solve problems to improve the quality of ...Show more UK / Canada / Europe / Singapore / Dubai / Australia-based • •Investment Banking or Private Equity Experts • • for a research project with a leading foundational model AI lab.
You are a good fit if you : - Have •...Show more 
Top Technical Skills & Requirements.Programming Expertise : 3+ years of hands-on experience with C# and Python, including building scalable applications and integrating ML models.API Development & M...Show more
This not-for-profit, 100-bed community hospital, located in one of Minnesota's most affluent suburbs, is seeking to add another BE / BC Endocrinologist to join its thriving practice.Join a collegial ...Show more
Online Research Participants (Pay up to $3,000 / study) - Flexible Earning Potential (Hiring Immediately)
Maxion Research • Mound, Minnesota, US
Part-time
Last updated: 30+ days ago • Promoted
Remote Financial Analyst - AI Trainer ($150 per hour)
Mercor • Shakopee, Minnesota, US
Remote
Full-time
Last updated: 5 days ago • Promoted
Remote Online Tasks - Earn Up to $1,500 / month Playing Games
Free Cash by Almedia • Victoria, MN, United States
Full-time
Last updated: 13 days ago • Promoted
Physical Therapist - Home Care
Interim HealthCare of the Twin Cities • Shakopee, MN, US
Full-time +1
Last updated: 30+ days ago • Promoted
Principal Clinical Content-Physician - UpToDate®, Physician Editor (Nephrology)
Wolters Kluwer • Victoria, MN, United States
Full-time
Last updated: 9 days ago • Promoted
Remote Research Study Contributor (Hiring Immediately)
Maxion Research • Mound, Minnesota, US
Remote
Part-time
Last updated: 30+ days ago • Promoted
Flexible Online Consumer Research Contributor (Hiring Immediately)
Earn Haus • Victoria, Minnesota, US
Full-time +1
Last updated: 30+ days ago • Promoted
AI / ML Engineer
IRIS Consulting LLC • Medina, MN, United States
Full-time
Last updated: 4 days ago • Promoted
Financial Planner - AI Development Expert ($150 per hour)
Mercor Inc • Shakopee, MN, United States
Full-time
Last updated: 4 days ago • Promoted
Research Study Participant
Reel Edge • Loretto, Minnesota, United States
Part-time
Last updated: 9 days ago • Promoted
Remote Research Contributor (Hiring Immediately)
Maxion Research • Chanhassen, Minnesota, US
Remote
Part-time
Last updated: 30+ days ago • Promoted
Remote Financial Planner - AI Trainer ($150 per hour)
Mercor Inc • Shakopee, MN, United States
Remote
Full-time
Last updated: 2 days ago • Promoted
Remote Financial Expert - AI Trainer ($150 per hour)
Mercor • Shakopee, Minnesota, US
Remote
Full-time
Last updated: 5 days ago • Promoted
Principal Clinical Content-Physician - UpToDate, Physician Editor (Nephrology)
Wolters Kluwer • Victoria, MN, United States
Full-time
Last updated: 9 days ago • Promoted
Remote M&A Associate - AI Trainer ($50-$60 / hour)
Data Annotation • Shakopee, MN, United States
Remote
Full-time +1
Last updated: 27 days ago • Promoted
Remote Financial Planner - AI Trainer ($150 per hour)
Mercor • Shakopee, Minnesota, US
Remote
Full-time
Last updated: 5 days ago • Promoted
AI / ML Engineer (Medina)
IRIS Consulting LLC • Medina, MN, US
Part-time
Last updated: 5 days ago • Promoted
Outpatient Endocrinology | $500K+ Proven Earnings | Affluent Minneapolis Suburb
Jackson Physician Search • Waconia, US
Full-time
Last updated: 30+ days ago • Promoted