Senior Associate Scientist In Vivo Pharmacology

Alnylam PharmaceuticalsCambridge, MA, United States

9 days ago

Job type

Full-time

Job description

Overview

The Research Department at Alnylam is seeking a passionate and motivated Senior Associate Scientist to join our dynamic, fast-paced and interdisciplinary in vivo Pharmacology team within the RNAi Discovery Platform group.

The successful candidate will have a background in animal research and biological sciences and bring a robust

technical in vivo and ex vivo skillset. The role will require strong interpersonal and organizational skills, the capacity to multi-task, and the ability to learn, master, and share new techniques. We particularly seek someone who is detail-oriented and who will flourish in a goal-driven team environment under tight deadlines. This individual will join a dynamic and highly collaborative team. Experience and passion for working with animals is a must.

This position is onsite and is located in Cambridge, MA.

Summary of Key Responsibilities

Contribute to the design of and independently execute in vivo studies to evaluate and characterize molecules for RNAi therapeutic delivery to a diverse array of tissues in a variety of animal models.
Conduct in vivo procedures in mice and rats, including therapeutic administration using established methodologies and tissue collections.
Conduct routine assays such as qPCR, western blot, ELISA to support in vivo studies, and begin to develop and troubleshoot novel assays.
Maintain safe and clean working environment by complying with procedures, rules, and regulations.
Responsible for high quality data entry and data analysis in a timely manner and prepare clearly articulated experimental reports and presentations.
Adapt quickly to changing priorities in a dynamic work environment.
Effectively and pro-actively multi-task and operate in a team-based environment.
Communicate openly and directly within and across teams and management and demonstrate the ability to effectively manage conflict.

Qualifications

BS / MS in Biology, Animal / Veterinary Sciences, Cell / Molecular Biology, Biochemistry, or related field with 3-5 years of laboratory experience in an industrial or academic setting working with animals.

Basic rodent in vivo skills (animal handling, subcutaneous / intravenous dosing, blood collection, and necropsy / tissue dissection expertise).

Experience in specialized in vivo techniques such as direct tissue injections or collections (IT, ICV, ICM, IVT, IA, OP, PO etc.) is a plus.

Excellent lab techniques and the ability to work independently are a prerequisite, experience in molecular biology techniques including RNA / DNA / protein extraction, qPCR, Western blot, ELISA a plus.

Demonstrate keen knowledge of experimental design, underlying scientific principles, and the ability to rigorously and independently analyze results, propose future directions, and generate clear reports.

Must be flexible, open to new tasks and challenges and able to work on tight deadlines.

Exceptional interpersonal skills and the ability to function at a high capacity within a fast-paced team environment.

Excellent attention to detail, organizational skills, eagerness to learn, and the ability to follow written and verbal instruction.

Working knowledge of standard Microsoft Office applications including Excel, GraphPAD, Outlook, PowerPoint, and Word.

Good documentation and record-keeping in compliance with ELN (Electronic Lab Notebook) guidelines required.

U.S. Pay Range

$76,300.00 - $114,500.00

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website : https : / / www.alnylam.com / careers

AboutAlnylam

We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values : fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

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Associate Scientist • Cambridge, MA, United States