Associate Director / Director, Computational ChemistryAerial Talent • South San Francisco, CA, US
No longer accepting applications
Associate Director / Director, Computational Chemistry
Aerial Talent • South San Francisco, CA, US
24 days ago
Job type
- Full-time
Job descriptionReports to SVP, Discovery Potential to have one or more direct reports Two lead targets : CNS oncology + neurodegeneration Financial runway forecasted through Spring 2027 ~25 full-time employees Provide strategic leadership and hands-on execution of our CADD efforts Collaborate closely with chemists and biologists on virtual screening, hit identification and structure-based design Guide the optimization of drug candidates that induce protein degradation Use machine-learning (ML) to build in silica models to predict DMPK properties Perform and automate high throughput molecular dynamics simulations to predict protein function and protein-ligand binding Utilize established tools and design new methods / tools Scientific programming as needed PhD in Computational Chemistry or related discipline 7+ years of relevant experience in drug discovery Computer aided drug design (CADD) / structure- and ligand-based design for small molecules Dotmatics, Schrodinger, MOE, OpenEye, or Gaussian software QSAR, QSPR, and conformational analysis Molecular mechanics and dynamics simulations Understanding of in vitro and in vivo DMPK principles Artificial Intelligence / Machine Learning (AI / ML) approaches to predictive modeling Quantum mechanics methods Statistical design of experiments (DoE) Multiparameter optimization Experimental assay methods and technology for protein-ligand interactions Programming with languages such as perl, python, or C++ Cheminformatics / database algorithms Emerging drug modalities such as covalent inhibitors, bifunctionals, molecular glues and / or PROTACs
Job Description
Well-funded biotech in SSF seeks a Computational Chemistry Director or Associate Director with experience in CADD- and structure-based design for lead optimization of small molecules to advance the pipeline of innovative therapeutics toward the clinic.
- Onsite in South San Francisco Monday through Friday (5 days / week)
Highlights :
Responsibilities :
Required Qualifications :
Preferred Skills & Knowledge :
Create a job alert for this search
Associate Director • South San Francisco, CA, US
Related jobs
If you are a current Jazz employee please apply via the Internal Career site.Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and ...Show more
Key Responsibilities : Lead the clinical science for CAR-T programs, collaborating on study design and execution Author and oversee clinical documents and regulatory submissions Analyze and inte...Show more A company is looking for a Director of UX Research to lead and scale their research practice.Key Responsibilities Lead high-impact research projects addressing critical and ambiguous questions ac...Show more A company is looking for a Director of Psychometrics and Research.Key Responsibilities Direct activities related to psychometrics, data systems, and applied quantitative research Oversee a team ...Show more A company is looking for an Associate Director of Quality Improvement Science.Key Responsibilities Lead and manage multiple complex projects as a Principal Investigator or team lead Mentor and s...Show more A company is looking for a Senior Director, Biostatistics.Key Responsibilities Oversee P&L management of the biostatistics department and develop the annual budget Ensure quality of all biostati...Show more A company is looking for an Associate Director, Investigations.Key Responsibilities : Support the implementation of the Global Compliance Program and enhance processes related to Ethics & Complian...Show more 
Associate Director for Collections and Operations - School of Law.Associate Director for Collections and Operations.The UC academic salary scales set the minimum pay determined by rank and step at ...Show more
Postdoctoral Research Associate, Computational Design.The Computational Design (CD) group of the AI Center at SRI International is seeking a strong and enthusiastic researcher with a Ph.Postdoctora...Show more Director of Innovative Programs (4801) Job 81039 - The Fung Institute.At the University of California, Berkeley, we are dedicated to fostering a community where everyone feels welcome and can thriv...Show more A company is looking for a Research Director / Principal Researcher.Key Responsibilities Lead the design and execution of complex research projects on K-12 education topics Manage project budgets,...Show more A company is looking for a Senior Director, Drug Product Development (Remote / Home Based).Key Responsibilities Directs the Small Molecule Drug Product Development team and manages budgetary resp...Show more If you are a current Jazz employee please apply via the Internal Career site.Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and ...Show more The President and the Regents of the University of California invite nominations and applications for the position of Director of the .
Lawrence Berkeley National Laboratory.LBNL,” “Berkeley Lab,” o...Show more 
This position can be 100% remote, but must be located in the United States.Dynavax is a commercial-stage biopharmaceutical company developing and commercializing novel vaccines to help protect the ...Show more A company is looking for an Associate Director, Underwriting Specialty Pricing, to lead underwriting initiatives and ensure appropriate risk assessment and pricing.
Key Responsibilities Lead the h...Show more A company is looking for a Senior Associate Study Manager to support the execution and monitoring of clinical studies.Key Responsibilities Support execution and monitoring of clinical studies and...Show more A company is looking for a Director of Engineering Integrations who can lead and implement technical integrations across the pharmacy ecosystem.
Key Responsibilities Own the end-to-end technical i...Show more If you are a current Jazz employee please apply via the Internal Career site.Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and ...Show more A company is looking for a Senior Scientific Director.Key Responsibilities Oversee the development of high-quality deliverables for Publications / Medical Affairs accounts Serve as a strategic par...Show more
Associate Director, Analytics & Insights Lead (Remote)
Jazz Pharmaceuticals • Palo Alto, CA, United States
Remote
Full-time
Last updated: 30+ days ago • Promoted
Senior Director Clinical Scientist
VirtualVocations • Concord, California, United States
Full-time
Last updated: 15 hours ago • Promoted • New!
Director of UX Research
VirtualVocations • Hayward, California, United States
Full-time
Last updated: 15 days ago • Promoted
Director of Psychometrics
VirtualVocations • Fremont, California, United States
Full-time
Last updated: 4 days ago • Promoted
Quality Improvement Science Director
VirtualVocations • Hayward, California, United States
Full-time
Last updated: 4 days ago • Promoted
Senior Director of Biostatistics
VirtualVocations • Hayward, California, United States
Full-time
Last updated: 19 days ago • Promoted
Associate Director of Investigations
VirtualVocations • Hayward, California, United States
Full-time
Last updated: 3 days ago • Promoted
Associate Director for Collections and Operations - School of Law
InsideHigherEd • Berkeley, California, United States
Full-time
Last updated: 6 days ago • Promoted
Postdoctoral Research Associate, Computational Design
SRI International • Menlo Park, CA, United States
Full-time
Last updated: 30+ days ago • Promoted
Director of Innovative Programs (4801) Job 81039 - The Fung Institute
InsideHigherEd • Berkeley, California, United States
Full-time
Last updated: 30+ days ago • Promoted
Research Director
VirtualVocations • Concord, California, United States
Full-time
Last updated: 30+ days ago • Promoted
Senior Director of Drug Development
VirtualVocations • Santa Clara, California, United States
Full-time
Last updated: 4 days ago • Promoted
Associate Director, Promotions - Oncology (Remote)
Jazz Pharmaceuticals • Palo Alto, CA, United States
Remote
Full-time
Last updated: 3 days ago • Promoted
Director of the Lawrence Berkeley National Laboratory
InsideHigherEd • Berkeley, California, United States
Full-time
Last updated: 2 days ago • Promoted
Director, Clinical Supplies
Dynavax Technologies • Emeryville, CA, United States
Full-time
Last updated: 20 days ago • Promoted
Associate Director Specialty Pricing
VirtualVocations • Concord, California, United States
Full-time
Last updated: 15 hours ago • Promoted • New!
Senior Associate Study Manager
VirtualVocations • Hayward, California, United States
Full-time
Last updated: 4 days ago • Promoted
Director of Engineering Integrations
VirtualVocations • Hayward, California, United States
Full-time
Last updated: 3 days ago • Promoted
Senior Director, Biological Analytical Development
Jazz Pharmaceuticals • Palo Alto, CA, United States
Full-time
Last updated: 18 days ago • Promoted
Senior Scientific Director
VirtualVocations • Concord, California, United States
Full-time
Last updated: 30+ days ago • Promoted