Senior Scientist, Cell Science

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ.

It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs).

SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications.

Alongside ongoing clinical trials.

SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development.

We offer an opportunity for you to learn and grow while making significant contributions to the company's success.   The Senior Scientist in the Cell Science Department is responsible for the development and optimization of CHO-based processes for the production of biotherapeutics.

This role requires broad expertise and the ability to contribute to both drug discovery and development projects.

A strong interest in bench work and hands-on experience with mammalian cell culture is essential.

This position requires a full-time onsite presence at our Redmond, WA location.

Responsibilities :

• Design and execute cell line development workflows, including vector design, transfection, clone screening, and selection for stable expression.
• Perform cell culture experiments involving mammalian cells (e.g., CHO cells) under sterile, aseptic conditions.
• Develop and optimize expression systems, including promoters, selection markers, and gene amplification strategies for high-yield production.
• Screen and characterize clones for productivity, stability, growth characteristics, and product quality attributes using molecular and biochemical assays.
• Collaborate with project teams and downstream process development scientists to execute protocols, experimental plans, critical production batches, and technology transfers.
• Manage and prioritize multiple projects while supporting and coordinating with other departments to advance company objectives and develop scalable, robust culture processes.
• Write and review Standard Operating Procedures (SOPs) and technical reports for regulatory filings.
• Prepare process transfer documents and cGMP documentation to support the successful implementation of process technologies in clinical and commercial manufacturing operations.
• Collaborate with R&D and the manufacturing team in China, participating in meetings and providing technical support as needed.
• Availability to work weekend and holiday shifts, as required.
• Perform other duties as assigned.

Qualifications :

Compensation and Benefits :

SystImmune offers a comprehensive benefits package including :

We welcome diverse talent and encourage all qualified applicants to apply.   Powered by JazzHR