Talent.com
Principal Product Manager, AI

Principal Product Manager, AI

Chan Zuckerberg InitiativeRedwood City, CA, United States
4 days ago
Job type
  • Full-time
Job description

The Team

CZI supports the science and technology that will make it possible to help scientists cure, prevent, or manage all diseases by the end of this century. While this may seem like an audacious goal, in the last 100 years, biomedical science has made tremendous strides in understanding biological systems, advancing human health, and treating disease.

Achieving our mission will only be possible if scientists are able to better understand human biology. To that end, we have identified four grand challenges that will unlock the mysteries of the cell and how cells interact within systems - paving the way for new discoveries that will change medicine in the decades that follow :

  • Building an AI-based virtual cell model to predict and understand cellular behavior
  • Developing state-of-the-art imaging systems to observe living cells in action
  • Instrumenting tissues to better understand inflammation, a key driver of many diseases
  • Engineering and harnessing the immune system for early detection, prevention, and treatment of disease

CZI's work in science includes grantmaking programs, open-source software development, and close collaboration with the Chan Zuckerberg Biohub Network. The CZ Biohub Network includes the San Francisco, Chicago, and New York Biohubs as well as the Chan Zuckerberg Imaging Institute. CZI also collaborates with institutional partners like the Kempner Institute for the Study of Natural & Artificial Intelligence at Harvard University. Join us in accelerating science.

The Opportunity

We are seeking a Principle Product Manager, AI with deep expertise at the intersection of artificial intelligence and biology. In this role, you will lead the development of innovative products that apply state-of-the-art AI to accelerate biological research.

As part of the Science Technology (SciTech) team, you will shape products that empower both computational and experimental researchers to use AI for in silico experimentation, hypothesis generation, data interpretation, and biological modeling. You will work across disciplines to identify high-impact opportunities where AI can meaningfully accelerate scientific progress, and translate them into impactful, scalable tools integrated within the CZI Virtual Cells Platform.

Examples include :

  • Multi-modal workflows for users to run inference on models using their own data for key tasks like data annotation and comparing data to a reference (e.g. healthy vs disease).
  • Tools that enable researchers to run and visualize in silico experiments using AI models, e.g. simulate how specific gene knockouts affect cell behavior in a virtual T-cell model.
  • Visualization library for visualizing and interacting with complex, multi-dimensional biological imaging data.
  • AI agents that assist experimental biologists in designing experiments by integrating prior datasets, model predictions, and literature insights.
  • What You'll Do

  • Define and drive the product strategy for AI-powered tools and agents that accelerate cell biology research.
  • Build AI-powered biological workflows that translate model outputs into usable insights for experimental and computational biologists.
  • Collaborate with scientific partners to deeply understand research needs and translate them into AI-driven solutions, bridging the gap between cutting-edge AI research and its real-world application in biological discovery.
  • Lead the development and deployment of workflows that leverage models developed by CZI and the scientific community to enable in silico experimentation.
  • Work closely with biologists, ML researchers, engineering, and design to deliver products that are intuitive, impactful, and well-integrated into researchers' workflows.
  • Collate and translate the needs of the CZ Imaging research teams into a platform strategy.
  • Continuously scout and evaluate emerging AI technologies (e.g., multi-modal models, agentic frameworks) and identify opportunities to integrate cutting-edge technologies.
  • What You'll Bring

  • 12+ years of product management or related experience, including at least 3 years working on AI or machine learning-powered products.
  • Strong background in AI / ML product development, with a track record of building products that bridge the gap between complex technology and domain-specific users, preferably in scientific or technical environments.
  • Experience applying AI models and agentic workflows (e.g., LLM-based agents, multi-step reasoning systems) to life science research problems.
  • Demonstrated ability to work collaboratively with interdisciplinary teams and external partners.
  • Excellent communication skills, with the ability to translate complex scientific and technical concepts for diverse audiences.
  • Passion for CZI's mission and a desire to drive scientific progress through technology.
  • (nice to have) Experience working with cutting-edge biological imaging technology.
  • Compensation

    The Redwood City, CA base pay range for a new hire in this role is $241,000-$331,000. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.

    As we grow, we're excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team's manager. The exact schedule will be at the hiring manager's discretion and communicated during the interview process.

    Benefits for the Whole You

    We're thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.

  • CZI provides a generous employer match on employee 401(k) contributions to support planning for the future.
  • Annual benefit for employees that can be used most meaningfully for them and their families, such as housing, student loan repayment, childcare, commuter costs, or other life needs.
  • CZI Life of Service Gifts are awarded to employees to "live the mission" and support the causes closest to them.
  • Paid time off to volunteer at an organization of your choice.
  • Funding for select family-forming benefits.
  • Relocation support for employees who need assistance moving to the Bay Area
  • And more!
  • If you're interested in a role but your previous experience doesn't perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.

    Explore our work modes, benefits, and interview process at www.chanzuckerberg.com / careers.

    #LI-Hybrid

    Create a job alert for this search

    Principal Product Manager • Redwood City, CA, United States

    Related jobs
    • Promoted
    Principal Product Manager - AI Products

    Principal Product Manager - AI Products

    Treasure DataMountain View, CA, US
    Full-time
    At Treasure Data, were on a mission to radically simplify how companies use data and AI to create connected customer experiences. Our intelligent customer data platform (CDP) drives revenue growth a...Show moreLast updated: 3 days ago
    • Promoted
    Product Manager AI

    Product Manager AI

    VirtualVocationsSanta Clara, California, United States
    Full-time
    A company is looking for a Product Manager AI & Search.Key Responsibilities Define and lead the strategic roadmap for the AI-powered search platform, focusing on advanced ML ranking models and pe...Show moreLast updated: 2 days ago
    • Promoted
    Principal Product Manager, AI Security, TotalAI

    Principal Product Manager, AI Security, TotalAI

    QualysFoster City, CA, United States
    Full-time
    Come work at a place where innovation and teamwork come together to support the most exciting missions in the world!.Principal Product Manager - AI Security and Data Security, TotalAI.Come work at ...Show moreLast updated: 30+ days ago
    • Promoted
    Staff Product Manager - AI / ML Platform

    Staff Product Manager - AI / ML Platform

    VisaFoster City, CA, United States
    Full-time
    Visa is a world leader in payments and technology, with over 259 billion payments transactions flowing safely between consumers, merchants, financial institutions, and government entities in more t...Show moreLast updated: 30+ days ago
    • Promoted
    • New!
    AI Technical & Product Manager

    AI Technical & Product Manager

    OSI EngineeringSan Jose, CA, US
    Full-time
    Seeking an AI Technical & Product Manager that can partner with internal AI platform teams, explore open-source alternatives and build AI agents for extended business unit.As the AI Technical & Pro...Show moreLast updated: 13 hours ago
    • Promoted
    Product Manager - Conversational AI

    Product Manager - Conversational AI

    ForhyreSunnyvale, CA, US
    Full-time
    Are you passionate about the future of AI and its potential to transform business operations?.We are seeking a highly skilled and motivated Product Manager to lead our Conversational AI team.As a P...Show moreLast updated: 30+ days ago
    • Promoted
    Platform Product Manager

    Platform Product Manager

    Brahma Consulting GroupRedwood City, CA, US
    Full-time
    As a Platform Product Manager, you will own the infrastructure that powers real-time 3D positioning technology—from how radio signals are received to the data pipelines that deliver location ...Show moreLast updated: 30+ days ago
    • Promoted
    AI Product Director

    AI Product Director

    VirtualVocationsFremont, California, United States
    Full-time
    A company is looking for a Director of AI Products & Platforms.Key Responsibilities Own the AI product lifecycle, defining roadmaps and delivering AI-powered features Drive customer-facing AI ex...Show moreLast updated: 2 days ago
    • Promoted
    Product Manager for AI Security

    Product Manager for AI Security

    VirtualVocationsFremont, California, United States
    Full-time
    A company is looking for a Product Manager : AI & Security.Key Responsibilities Define and execute the product roadmap for vulnerability discovery algorithms and coverage optimization Drive prior...Show moreLast updated: 2 days ago
    • Promoted
    Sr. Director, Principal Product Manager - AI / ML Platforms

    Sr. Director, Principal Product Manager - AI / ML Platforms

    VisaFoster City, CA, United States
    Full-time
    Visa is a world leader in payments and technology, with over 259 billion payments transactions flowing safely between consumers, merchants, financial institutions, and government entities in more t...Show moreLast updated: 30+ days ago
    • Promoted
    Senior AI Product Manager

    Senior AI Product Manager

    VirtualVocationsSan Jose, California, United States
    Full-time
    A company is looking for a Senior Product Manager, AI.Key Responsibilities Lead the development of AI and LLM-powered products to enhance customer experience Collaborate with engineering, data s...Show moreLast updated: 30+ days ago
    • Promoted
    Product Manager, ddPCR Consumables and Reagents

    Product Manager, ddPCR Consumables and Reagents

    Bio-Rad LaboratoriesPleasanton, CA, United States
    Full-time
    Join Us in Transforming Research and Diagnostics with ddPCR.Are you a passionate product manager ready to make a global impact? Bio-Rad Laboratories is seeking a dynamic and driven Product Manager ...Show moreLast updated: 11 days ago
    • Promoted
    AI Manager

    AI Manager

    VirtualVocationsFremont, California, United States
    Full-time
    A company is looking for an AI Manager to drive AI adoption and integration into business operations.Key Responsibilities Drive the rollout of the AI roadmap across all functions to improve produ...Show moreLast updated: 2 days ago
    • Promoted
    AI Product Management Leader

    AI Product Management Leader

    VirtualVocationsFremont, California, United States
    Full-time
    A company is looking for a Product Management Leader, AI.Key Responsibilities Drive AI product management strategy across a global portfolio Define the integration of AI / ML technologies into ent...Show moreLast updated: 23 days ago
    • Promoted
    Product Marketing, Senior Manager, AI & Analytics

    Product Marketing, Senior Manager, AI & Analytics

    Medallia, Inc.Pleasanton, CA, United States
    Full-time
    Medallia is the pioneer and market leader in Experience Management.Our award-winning SaaS platform, Medallia Experience Cloud, leads the market in the management of experiences, insights, and actio...Show moreLast updated: 23 days ago
    • Promoted
    Senior Product Manager - AI Tooling

    Senior Product Manager - AI Tooling

    VirtualVocationsHayward, California, United States
    Full-time
    A company is looking for a Senior Product Manager - AI and Developer Tooling (CI / CD, MCP & CLI).Key Responsibilities Own the developer tooling roadmap across CLIs, SDKs, templates, and pipelines-...Show moreLast updated: 2 days ago
    • Promoted
    Principal Product Manager

    Principal Product Manager

    VirtualVocationsFremont, California, United States
    Full-time
    A company is looking for a Principal Product Manager.Key Responsibilities Develop and evolve user acquisition and enrollment platforms Conduct quantitative analysis and user research to improve ...Show moreLast updated: 30+ days ago
    • Promoted
    Product Research Manager

    Product Research Manager

    VirtualVocationsFremont, California, United States
    Full-time
    A company is looking for a Senior Manager, Product Research.Key Responsibilities : Convert global & regionalized phishing & social engineering threats into effective training content Own and cura...Show moreLast updated: 1 day ago
    • Promoted
    Senior Product Manager, AI-Powered Engagement - Contractor

    Senior Product Manager, AI-Powered Engagement - Contractor

    Five9San Ramon, CA, US
    Full-time
    Join us in bringing joy to customer experience.Five9 is a leading provider of cloud contact center software, bringing the power of cloud innovation to customers worldwide.Living our values everyday...Show moreLast updated: 30+ days ago
    • Promoted
    Senior Product Manager, AI Engagement

    Senior Product Manager, AI Engagement

    VirtualVocationsHayward, California, United States
    Full-time
    A company is looking for a Senior Product Manager, AI-Powered Engagement - Contractor.Key Responsibilities : Define, prioritize, and deliver AI-powered features for intelligent customer engagement...Show moreLast updated: 23 hours ago