Graduate Intern – R&D Predictive Nonclinical Safety Models

Career Category

College Job

Job Description

Join Amgens Mission of Serving Patients

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our award-winning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Graduate Intern R&D Predictive Nonclinical Safety Models

What You Will Do

Lets do this. Lets change the world. During this program you will internalize reproduce and validate published small molecule predictive safety models for drug-induced liver injury and cardiovascular risk assessment to better understand their performance interpretability and applicability to real-world toxicological data. Your work will help Amgen bridge the gap in predictive safety modeling and biological understanding a critical step toward designing safer and more effective medicines.

This internship offers a unique opportunity for graduate students to apply advanced data science methods to meaningful biological problems under the mentorship of experienced computational scientists and toxicologists. The successful candidate will work closely with scientists across data science and toxicology to reproduce benchmark and refine existing models using in-house and public datasets.

• Reproduce and evaluate a defined set of published machine learning models for toxicity prediction and other safety endpoints.
• Implement and adapt models using Python and R applying best practices in model development validation and documentation.
• Compare and benchmark models using public and internal datasets to understand their robustness and translational relevance.
• Assess model performance using public and internal datasets to understand their robustness translational relevance and identify opportunities for improvement / expansion or integration into existing workflows.
• Summarize findings and recommendations in clear documentation visualizations and reports to cross-functional teams.
• Work with data science colleagues to define a model assessment protocol for future model evaluations.

What We Expect of You

We are all different yet we all use our unique contributions to serve patients. The TSRS Data Sciences group is seeking a highly motivated Graduate Student Intern to join our interdisciplinary Computational Safety team advancing the use of machine learning and AI for predictive safety science .

Basic Qualifications :

Amgen requires that all individuals applying for a grad internship at Amgen must meet the following criteria :

Preferred Qualifications :

What You Can Expect of Us

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture well support your journey every step of the way.

The base pay range for this opportunity in the U.S. is $30-$40 per hour

Apply now and make a lasting impact with the Amgen team.

In any materials you submit you may redact or remove age-identifying information such as age date of birth or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Sponsorship

Candidates must be authorized to work in the U.S. for the duration of this program. Sponsorship for future FTE roles is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Salary Range

Required Experience :

Intern

Key Skills

Laboratory Experience,Vendor Management,Design Controls,C / C++,FDA Regulations,Intellectual Property Law,ISO 13485,Research Experience,SolidWorks,Research & Development,Internet Of Things,Product Development

Employment Type : Full-Time

Experience : years

Vacancy : 1

Hourly Salary Salary : 30 - 40