Cell Line Development Research Associate

Description :

Cell Line Development Research Associate is involved in the creation of stable cell lines for the recombinant adeno-associated viral vector (rAAV) production processes . He / she executes experiments, produces relevant documentation, and works under supervision. He / she will be responsible for :

• Culturing mammalian cells for viral production in shake flasks, spinner flasks, spin tubes, deep well and automation platforms.
• Performing experiments in the development, optimization and scale-up of AAV producer cell lines.
• Preparing process development protocols, data analysis summaries, technical reports, and other relevant process documentation.
• Optimization of transfection and transduction protocols for newly engineered cell lines.
• Maintaining an accurate laboratory notebook.
• Ensuring work conforms to applicable quality and safety standards.
• Participating on project teams (as needed).

Education and Experience Requirements

B.S. with 3-6 years of experience, MS.c with 2-5 years of relevant scientific or technical experience in the life sciences industry or equivalent

Key Skills, Abilities, and Competencies :

Hands-on experience in mammalian cell culture production processes is a critical requirement. This includes small scale (shaker flasks, spinner flasks, spin tubes, deep well) and / or benchtop bioreactor scale.

Experience with creation, analysis and characterization of new engineered cell lines and stability studies (subcloning, clonal expansion, transient transfection and expression screening) is a strong plus.

Experience in molecular biology techniques (plasmid design, molecular cloning, SDS-PAGE / western blotting, qPCR, etc) is a strong plus.

Automation and ELN experience is a strong plus.

Effective communication skills (verbal, written, interpersonal).

Industry experience is a plus but not required

Basic Knowledge on AAV biology is a plus.

Must be able to interact with cross-functional teams.

Analytical and problem-solving skills.

Ability to manage time effectively.

Experience in laboratory automation hardware and software is a plus.

Teamwork is a must.

Must be able to lift 25 pounds.

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Additional Details