Talent.com
Senior Principal Software Engineer

Senior Principal Software Engineer

F. Hoffmann-La Roche GruppeSanta Clara, CA, United States
19 days ago
Job type
  • Full-time
Job description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

Our team is composed of forward-thinking scientists, engineers, and researchers who are passionate about revolutionizing healthcare through innovation.

We are seeking a highly motivated and experienced Software Engineer to join our growing team and contribute to the development of high-performance, high-quality NGS bioinformatics algorithms.

The Opportunity :

As a Software Engineer specializing in Next Generation Sequencing Bioinformatics at Roche Diagnostics, you will play a critical role in designing, developing, and optimizing cutting-edge algorithms to extract meaningful insights from genomic data. This position offers a unique opportunity to work on innovative projects that impact the fields of diagnostics and precision medicine. You will work closely with cross-functional teams of biologists, data scientists, and software engineers to build robust, scalable, and efficient software solutions.

Algorithm Development : Design and implement high-performance algorithms for NGS data analysis, including variant calling, quality control, and data preprocessing.

Optimization : Continuously refine and optimize bioinformatics solutions for handling large-scale genomic datasets with improved efficiency and performance.

Collaboration : Partner with biologists, data scientists, and engineers to meet the unique challenges of NGS diagnostics and research workflows.

Software Integration : Seamlessly incorporate bioinformatics tools into Roche's software ecosystem, ensuring compatibility and robustness.

Quality Assurance : Maintain the integrity of analytical results by crafting rigorous test suites and working alongside QA teams.

Innovation and Leadership : Stay at the forefront of NGS and bioinformatics trends while mentoring junior engineers and driving innovation within the company.

Who You Are :

You hold a Bachelor's or higher degree in Computer Science, Bioinformatics, Computational Biology, or a related field.

You have at least 8-10 years of proven experience in developing high quality software and algorithms for NGS data analysis.

You have strong proficiency in programming languages such as C++ and Python.

You have a track record of proficiency in relevant bioinformatics tools and libraries.

Demonstrated progression in experience with parallel computing, optimization, and performance tuning.

You have strong problem-solving skills and attention to detail.

You have excellent communication and teamwork skills.

Preferred Qualifications :

Experience working in a regulated environment (e.g., FDA, CLIA).

Experience with GPU development and optimization.

The expected salary range for this position is based on the primary location of Pleasanton, CA is $189,200 - $270,300. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed in this link.

Who we are

A healthier future drives us to innovate. Together, more than 100,000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

#J-18808-Ljbffr

Create a job alert for this search

Principal Software Engineer • Santa Clara, CA, United States

Related jobs
  • Promoted
Principal Software Engineer

Principal Software Engineer

MediumSan Francisco, CA, United States
Full-time
Viant’s customers use the Demand Side Platform (DSP) to set up, run and monitor ad campaigns.The platform team owns a complex set of backend services and the frontend UI that make up the DSP.These ...Show moreLast updated: 19 days ago
  • Promoted
Principal Scientific Software Engineer

Principal Scientific Software Engineer

GenentechSan Francisco, CA, United States
Full-time
It’s what drives us to innovate.To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more ...Show moreLast updated: 30+ days ago
  • Promoted
Principal Engineer / Software Architect

Principal Engineer / Software Architect

PHILSan Francisco, CA, United States
Full-time
Founded in 2015, PHIL is a Series D health-tech startup that is building a platform that interfaces between doctors, pharmacies, and patients to streamline the process of patients receiving prescri...Show moreLast updated: 30+ days ago
  • Promoted
Partner Engineering - Senior Software Engineer

Partner Engineering - Senior Software Engineer

Sprinter Health, Inc.San Francisco, CA, United States
Full-time
Sprinter Health is rethinking how healthcare gets delivered—bringing high-quality, preventive care directly into patients’ homes using smart logistics, real-time clinical ops, and deeply integrated...Show moreLast updated: 12 days ago
  • Promoted
Principal Software Engineer

Principal Software Engineer

SysdigSan Francisco, CA, United States
Full-time
At Sysdig, we believe cloud security isn't a compromise - it's a promise.From the start, our mission has been clear : to help organizations secure innovation in the cloud, the right way.We created F...Show moreLast updated: 1 day ago
  • Promoted
Senior Software Engineer, Partner Engineering

Senior Software Engineer, Partner Engineering

Ellation, Inc.San Francisco, CA, United States
Full-time
Senior Software Engineer, Partner Engineering.Founded by fans, Crunchyroll delivers the art and culture of anime to a passionate community. We super-serve over 100 million anime and manga fans acros...Show moreLast updated: 30+ days ago
  • Promoted
Senior / Principal Software Engineer

Senior / Principal Software Engineer

Bellota LabsRedwood City, CA, United States
Full-time
Driven by innovation, game integrity, and exceptional customer experiences, we are on a mission to set new standards in online gaming. Senior / Principal Software Engineer.This key role will help shap...Show moreLast updated: 30+ days ago
  • Promoted
Principal Software Engineer ( Core Banking Systems)

Principal Software Engineer ( Core Banking Systems)

First Citizens BankSanta Clara, CA, US
Full-time
This is a hybrid role, with the expectation that time working will regularly take place inside and outside of a company office. This position provides expert technical guidance on large, complex, an...Show moreLast updated: 2 days ago
  • Promoted
Sr. Staff or Principal Software Engineer

Sr. Staff or Principal Software Engineer

Piper CompaniesSan Francisco, CA, United States
Full-time
Staff or Principal Software Engineer.SAI (Switch Abstraction Interface) with SONiC (Software for Open Networking in the Cloud). This is a full-time, high-impact role focused on enabling performant c...Show moreLast updated: 13 days ago
  • Promoted
Senior Principal Software Engineer

Senior Principal Software Engineer

F. Hoffmann-La Roche GruppeSanta Clara, CA, United States
Full-time
At Roche you can show up as yourself, embraced for the unique qualities you bring.Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted ...Show moreLast updated: 19 days ago
  • Promoted
Sr. Principal Software Engineer - Analytics

Sr. Principal Software Engineer - Analytics

Coupa Software Inc.Foster City, CA, United States
Full-time
Principal Software Engineer - Analytics.Coupa makes margins multiply through its community-generated AI and industry-leading total spend management platform for businesses large and small.Coupa AI ...Show moreLast updated: 30+ days ago
  • Promoted
Senior Software Engineer, Core Platform

Senior Software Engineer, Core Platform

CascaSan Francisco, CA, United States
Full-time
Casca is building AGI for banking.We’re replacing decades-old legacy systems with AI-native technology that automates 90% of the manual work humans once had to do. We’re seeking a Senior Software En...Show moreLast updated: 30+ days ago
  • Promoted
Senior Software Engineer

Senior Software Engineer

MediumRedwood City, CA, United States
Full-time
Propel Software transforms the way product companies work.Our product value management platform connects commercial and product teams to optimize decision making, drive process efficiencies, and en...Show moreLast updated: 19 days ago
  • Promoted
Senior Software Engineer, Platform

Senior Software Engineer, Platform

Menlo VenturesMountain View, CA, United States
Full-time
This is an amazing opportunity to be an engineer in a high-growth, high-potential startup.In this role, you will be part of the Platform team and responsible for architecting, designing, developing...Show moreLast updated: 15 days ago
  • Promoted
Principal Software Engineer, ChatGPT for Work

Principal Software Engineer, ChatGPT for Work

OpenAISan Francisco, CA, United States
Full-time
The ChatGPT for Work team works across research, engineering, product, and design to bring OpenAI’s technology to consumers and businesses. We seek to learn from deployment and distribute the benefi...Show moreLast updated: 13 days ago
  • Promoted
Principal Software Engineer, Crusoe Cloud

Principal Software Engineer, Crusoe Cloud

Crusoe Energy Systems LLCSan Francisco, CA, United States
Full-time
Cruose's mission is to accelerate the abundance of energy and intelligence.We’re crafting the engine that powers a world where people can create ambitiously with AI — without sacrificing scale, spe...Show moreLast updated: 30+ days ago
  • Promoted
Principal Software Engineer – AI Systems

Principal Software Engineer – AI Systems

Walmart CanadaSunnyvale, CA, United States
Full-time
Balance functional requirements with non-functional goals such as reliability, latency, and security.Generative AI / LLMs • • in production. Strong coding skills in • •Python (preferred) • • and at least o...Show moreLast updated: 17 days ago
  • Promoted
Software Engineer (Principal)

Software Engineer (Principal)

Menlo VenturesSan Francisco, CA, United States
Full-time
Biotechnology is rewriting life as we know it, from the medicines we take, to the crops we grow, the materials we wear, and the household goods that we rely on every day. But moving at the new speed...Show moreLast updated: 30+ days ago