Director, Antibody Development & Engineering

Join to apply for the Director, Antibody Development & Engineering role at GondolaBio .

This role offers a competitive base pay range of $220,000.00 / yr - $250,000.00 / yr . Actual compensation will be based on your skills and experience and will include performance bonuses and equity.

Base pay range

$220,000.00 / yr - $250,000.00 / yr

Company Background

GondolaBio is a biopharmaceutical company focused on developing next‑generation therapeutics for genetic diseases. Originally carved out of BridgeBio, GondolaBio secured $300M in private financing from external investors in 2024 and became an independent company within the BridgeBio ecosystem. GondolaBio aims to leverage cutting‑edge biological research to discover, create, test, and deliver transformative medicines to treat patients who suffer from genetic diseases.

To learn more about our company and current pipeline of drug candidates, visit us at https : / / gondolabio.com .

Who You Are

We are looking for a highly motivated and innovative scientist to lead the antibody discovery for a newly‑formed GondolaBio program. The selected candidate will work within a fast‑paced, interactive, and innovative research team to lead discovery campaigns for novel antibodies. This role will lead the development of immunological functional assays, CRO management, oversight of antibody discovery campaign, contribute to future regulatory submissions, and participate in cross‑functional meetings. Excellent communication and interpersonal skills, as well as strong technical and scientific abilities, are required.

Responsibilities & Contributions

• Design, develop and lead multiple antibody discovery campaign efforts with CROs, including biochemical and functional assay screening
• Lead antibody engineering efforts for affinity maturation campaigns, developability, and immunological enhancement
• Lead the development of preclinical animal models with CROs to assess lead candidates
• Engage in scientific discussion with collaborators and management to evaluate ongoing projects
• Develop and optimize SOPs, validation protocols, provide technical assistance and train research associates as needed
• Oversee wet lab activities including tissue culture, PBMC isolation, protein expression and purification, functional assays, and flow cytometry
• Maintain strong understanding of state‑of‑the‑art protein engineering
• Collaborate with cross‑functional teams, including DMPK, toxicology, clinical development, regulatory to advance our therapeutic candidates from preclinical stages toward clinical development in a fast‑paced, dynamic environment
• Represent the program scientifically to internal and external audiences
• Contribute to the drafting of translation‑ and pharmacology‑related sections of regulatory documents including INDs
• Contribute to due diligence and gap analysis on potential new GondolaBio assets as needed

Education, Experience & Skills Requirements

What We Offer

Seniority Level

Director

Employment type

Full‑time

Job function

Science

Location

Mountain View, CA

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