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Program Manager, GCTI Manufacturing

Program Manager, GCTI Manufacturing

Salem Hospital NSMCCambridge, MA, US
30+ days ago
Job type
  • Full-time
Job description

Program Manager, Gene And Cell Therapy Institute

The Gene And Cell Therapy Institute (GCTI) is a newly launched, system-wide initiative within Mass General Brigham (MGB), designed to accelerate the translation of cutting-edge gene and cell therapy research into transformative clinical applications. GCTI fosters a unified ecosystem to support investigators across MGB, advancing platforms and programs that aim to deliver next-generation therapeutics to patients. Leveraging the unique strengths of a world-class academic hospital network, GCTI positions MGB as a global leader in gene and cell therapy innovation. We are seeking a strategic, experienced, and mission-driven Program Manager to help lead the operational, scientific, and translational components of the Institute's growing portfolio.

This individual will manage cross-functional programs, coordinate with internal and external stakeholders, and play a critical role in overseeing the development, execution, and evaluation of GCTI-supported gene and cell therapy initiatives.

Principal Duties And Responsibilities :

  • Manufacturing Program Management
  • Regulatory & Translational Management
  • Manufacturing Core & GMP Support
  • Administrative Management

Qualifications :

  • Bachelor's Degree Related Field Of Study required; PhD or MS with equivalent experience in life sciences, bioengineering, molecular biology, or related fields highly preferred
  • At least 5-7 years of Program Management Experience required
  • At least 1-2 years of Supervisory / Team Leadership Experience required
  • At least 5 years of relevant experience in gene therapy, cell therapy, viral vector development, or biologics program management highly preferred
  • Demonstrated leadership in cross-functional program or portfolio management, particularly in translational or early-stage development environments.
  • Familiarity with GMP manufacturing, assay development, and quality / regulatory processes.
  • Strong understanding of clinical development and commercialization pathways for advanced therapies.
  • Experience in academic and / or industry settings, preferably within a matrixed or multi-site institution.
  • Excellent communication, strategic planning, and interpersonal skills; capable of working with technical and non-technical stakeholders.
  • Knowledge, Skills, and Abilities :

  • Highly functioning, detail-oriented, and analytical candidate who can think strategically and holistically about organizational expansion and across multiple departments / units.
  • Proven experience in early stage biologics process development, manufacturing, and process characterization
  • Demonstrated ability to function in a collaborative quality and CMC environment.
  • Demonstrated ability to generate and finalize Standard Operating Procedures, corresponding Forms, and other manufacturing and analytical protocols.
  • Knowledge of technology transfer and IP strategy in biomedical innovation.
  • Experience managing programs funded by NIH, FDA, or other major federal or philanthropic agencies.
  • Familiarity with IND-enabling studies, regulatory science, and the evolving landscape of gene / cell therapy policy.
  • Proven track record of working in or with core facilities, academic research centers, or translational research environments
  • Strong communication skills and ability to connect at all levels of the organization.
  • Proven manage with ability to influence others without direct authority.
  • Self-starter but also a strong desire to contribute and work collaboratively to achieve goals.
  • Must be comfortable working within an evolving, sometimes ambiguous environment / structure.
  • Ability to handle sensitive and confidential information required.
  • Experience with quality systems preferred.
  • Familiarity with the commercialization of research innovations is preferred.
  • Working Conditions :

  • Mandatory onsite role; position may require travel to MGB hospitals and affiliated sites.
  • Occasional off-hours meetings with partners or collaborators may be required.
  • Remote Type : Onsite

    Work Location : 65 Landsdowne Street

    Scheduled Weekly Hours :

    40

    Employee Type : Regular

    Work Shift :

    Day (United States of America)

    Pay Range : Grade : 7

    EEO Statement :

    Mass General Brigham Incorporated is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and / or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.

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