Talent.com
Director, Statistical Programming
Director, Statistical ProgrammingAlumis • South San Francisco, CA, US
Director, Statistical Programming

Director, Statistical Programming

Alumis • South San Francisco, CA, US
27 days ago
Job type
  • Full-time
Job description

Job Description

Job Description

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.

We are seeking an experienced Statistical Programming Director to lead programming strategy, execution, and oversight across one or more drug development programs. This role is accountable for ensuring high-quality programming deliverables in accordance with SOPs, CDISC standards, and global regulatory requirements. The Director will provide hands-on technical leadership, manage internal and external programming resources, and partner cross-functionally to support submissions, publications, and study delivery. This role is ideal for someone who thrives at the intersection of regulatory rigor and modern data science technologies — with opportunities to shape how we integrate dynamic visualization, automation, and open-source & AI / ML tools into a high-quality submission and evidence generation environment.

Essential Responsibilities :

Program Leadership & Strategy

  • Lead statistical programming activities at the study, indication, or program level, including ISS / ISE.
  • Develop and execute programming strategies to support regulatory submissions, publications, ad hoc and exploratory analysis, and internal / external communications.
  • Ensure programming work adheres to SOPs, CDISC standards as applicable, and regulatory expectations.
  • Strong ability to communicate analytical results to non-technical stakeholders and translate findings into actionable scientific or business decisions.

Technical Excellence & Oversight

  • Provide technical leadership on programming conventions, standards, specifications, and solutions to complex data challenges.
  • Oversee the development and implementation of programming standards, reusable packages utilities, and process improvements.
  • Proficiency in R, Python, and / or other programming languages and visualization techniques.
  • Knowledge of modern version control systems and open-source software development techniques
  • Expertise in transforming and analyzing various data types related to clinical trials, including digital health, genomic and biomarkers
  • Ability to analyze complex clinical, preclinical, or real-world datasets to generate insights that inform drug development strategy
  • Cross-Functional Collaboration

  • Partner closely with Statisticians, Data Management, Clinical Operations, Medical Monitoring, and Medical Writing.
  • Participate in review of key study documents (e.g., SAPs, CRFs, DMPs, database specs, DMC charters).
  • Serve as a programming point of contact for internal teams and external CRO partners.
  • Process, Compliance & Quality

  • Drive best practices and continuous improvement initiatives, including SOP development and CDISC implementation.
  • Understanding of regulatory and compliance standards relevant to data analysis in pharma (e.g., GxP, data integrity, audit readiness)
  • Team Leadership

  • Lead and mentor statistical programming staff and oversee CRO / vendor programmers.
  • May oversee or manage a programming team responsible for study-level and project-level deliverables.
  • Innovation & Modernization Initiatives

  • Lead the continued evolution of our computing environment to incorporate automated workflows, modular code, and modern visualization tools.
  • Drive initiatives for leveraging programming software such as R and R shiny, python, and open-source environments to enable dynamic data exploration.
  • Champion reproducible pipelines using tools such as Git, Quarto, and R Markdown.
  • Contribute to internal packages, re-usable code libraries, and process automation to accelerate insights and submissions.
  • Explore GenAI, AI / ML applications that will optimize workflow and evolve evidence insight generations
  • The Ideal Candidate :

  • Advanced degree (MS or PhD) in statistics, computer science, life sciences, or a related field strongly preferred, with a minimum of 8–10 years of statistical programming experience in drug development.
  • Extensive experience leading programming support for global regulatory submissions (FDA, EMA, CDE).
  • Prior experience in early- and late-phase studies with integrated analyses is strongly preferred.
  • Advanced programming skills in R, Python with strong knowledge in clinical data visualization and exploration.
  • Working knowledge in open-source software development environments
  • Comfortable working in fast-paced, ambiguous environments and proactively identifying data-driven opportunities.
  • Collaborative mindset and willingness to mentor team members and contribute to a culture of knowledge sharing. Demonstrated ability to lead programming teams and oversee vendor partnerships.
  • Strong cross-functional communication skills, able to influence and collaborate effectively.
  • Detail-oriented, meticulous, and committed to quality and accuracy.
  • This role is located in South San Francisco, CA, with an on-site presence expected Tuesday through Thursday. Remote candidates may remain off-site but should be willing to travel regularly for team collaboration.

    Alumis Inc. is an equal opportunity employer.

    The salary range for this position is $200,000 USD to $245,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company's compensation practices.

    Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.

    Other benefits include :

  • Health insurance premiums paid at 90% for employee, 80% for dependents
  • Free access to Genentech Bus & Ferry Share program
  • $100 monthly cell phone stipend
  • Unlimited PTO for Exempt employees
  • Free onsite gym and a kitchen stocked with yummy snacks and drinks!
  • We are a hard-working, collaborative team on a mission to transform patient's lives and we aspire to elevate , challenge and nurture one another along the way.

    Create a job alert for this search

    Director Statistical Programming • South San Francisco, CA, US

    Similar jobs
    Senior Director, Statistical Programming

    Senior Director, Statistical Programming

    Arcellx, Inc. • Redwood City, CA, United States
    Full-time
    Arcellx isa public, clinical-stage biotechnology company reimagining cell therapy by engineering innovative immunotherapies for patients with cancer and other incurable diseases.We believe that cel...Show more
    Last updated: 28 days ago • Promoted
    Director, Statistical Programming

    Director, Statistical Programming

    4D Molecular Therapeutics • Emeryville, CA, United States
    Full-time
    Attention recruitment agencies : .All agency inquiries are vetted through 4DMT's internal Talent Acquisition team.No unsolicited resumes will be accepted. The 4DMT Talent Acquisition team must express...Show more
    Last updated: 2 days ago • Promoted
    Director, Strategy

    Director, Strategy

    EMC Research • Oakland, CA, United States
    Full-time
    National Polling and Market Research firm seeks.Our mission is : to partner with our clients to solve problems through well-executed research conducted by curious and passionate strategists who expl...Show more
    Last updated: 9 days ago • Promoted
    Director, Statistical Programming

    Director, Statistical Programming

    Alumis • South San Francisco, California, US
    Full-time
    Job Description Job Description Alumis Inc.Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally cha...Show more
    Last updated: 3 days ago • Promoted
    Senior Director, Biostatistics

    Senior Director, Biostatistics

    Olema Oncology • San Francisco, CA, United States
    Full-time
    Olema Oncology is dedicated to developing better medicines for breast cancer and beyond.Our lead program, palazestrant (OP-1250), is a complete estrogen receptor antagonist (CERAN) currently in dev...Show more
    Last updated: 30+ days ago • Promoted
    Director of Data Science, Ads Measurement & Attribution

    Director of Data Science, Ads Measurement & Attribution

    Pinterest • San Francisco, CA, United States
    Full-time
    Millions of people around the world come to our platform to find creative ideas, dream about new possibilities and plan for memories that will last a lifetime. At Pinterest, we're on a mission to br...Show more
    Last updated: 30+ days ago • Promoted
    Director of Research

    Director of Research

    University of California - San Francisco • San Francisco, CA, United States
    Full-time
    The job posting you are looking for has expired or the position has already been filled.If you are interested in one of our other opportunities, please visit our career site.Show more
    Last updated: 6 days ago • Promoted
    Director, Statistical Programming Standards Infrastructure

    Director, Statistical Programming Standards Infrastructure

    Exelixis • Alameda, CA, United States
    Full-time
    Director Of Statistical Programming Standards Infrastructure / h2pThe Director of Statistical Programming Standards Infrastructure provides strategic leadership and oversight for the development, imp...Show more
    Last updated: 1 day ago • Promoted
    Director, Statistical Programming Standards & Infrastructure

    Director, Statistical Programming Standards & Infrastructure

    Exelixis, Inc. • Alameda, CA, United States
    Full-time
    This role ensures compliance with regulatory requirements, industry standards (e.CDISC), and internal quality processes.The Director will partner with cross-functional teams, including Biostatistic...Show more
    Last updated: 30+ days ago • Promoted
    Director of Biostatistics

    Director of Biostatistics

    Confidential • San Francisco, CA, United States
    Full-time
    Pioneering biotechnology company focused on innovative solutions.Our dynamic biotechnology company is on the lookout for a strategic and innovative Director of Biostatistics.In this pivotal role, y...Show more
    Last updated: 6 days ago • Promoted
    Director, Biostatistics

    Director, Biostatistics

    REVOLUTION Medicines • Redwood City, CA, United States
    Full-time
    Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline com...Show more
    Last updated: 28 days ago • Promoted
    Associate Director, Scientific Programming

    Associate Director, Scientific Programming

    BeOne Medicines • Emeryville, CA, United States
    Full-time
    The Associate Director, Statistical Programming Project Lead will be responsible for a product area and support multiple indication development programs. The incumbent will lead the global developme...Show more
    Last updated: 7 days ago • Promoted
    Director, Biostatistics

    Director, Biostatistics

    Gilead Sciences, Inc. • Foster City, CA, United States
    Full-time
    At Gilead, we’re creating a healthier world for all people.For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapi...Show more
    Last updated: 30+ days ago • Promoted
    Director Biostatistics

    Director Biostatistics

    Barrington James • Emeryville, CA, United States
    Full-time
    Director of Biostatistics - Biotechnology Company - Hybrid - Oncology.Barrington James is proud to partner with a highly respected well established biotech client, seeking a Director of Biostatisti...Show more
    Last updated: 1 day ago • Promoted
    Associate Director of Statistical Programming

    Associate Director of Statistical Programming

    VirtualVocations • San Francisco, California, United States
    Full-time
    A company is looking for an Associate Director of Data Standards & Statistical Programming.Key Responsibilities Plan and track statistical programming activities including SAS macro development ...Show more
    Last updated: 7 days ago • Promoted
    Senior Quantum Engineer, Readout

    Senior Quantum Engineer, Readout

    Rigetti Computing • Berkeley, CA, US
    Full-time
    As Senior Quantum Engineer, Readout, you will optimize superconducting qubit readout and reset on Rigetti’s quantum processors and fault-tolerant prototypes. You will lead a range of experimen...Show more
    Last updated: 30+ days ago • Promoted
    Director, Statistical Programming

    Director, Statistical Programming

    GILEAD • San Mateo, CA, United States
    Full-time
    Director, Clinical Data Science.At Gilead, we're creating a healthier world for all people.For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer working r...Show more
    Last updated: 8 days ago • Promoted
    Director, Statistical Programming

    Director, Statistical Programming

    Gilead Sciences • Foster City, CA, United States
    Full-time
    At Gilead, we're creating a healthier world for all people.For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapi...Show more
    Last updated: 28 days ago • Promoted