Director of Facilities, Laboratory Operations and EHS
Olema Oncology is dedicated to developing better medicines for breast cancer and beyond. Our lead program, palazestrant (OP-1250), is a complete estrogen receptor antagonist (CERAN) currently in development for metastatic breast cancer with blockbuster potential as a monotherapy and in combination in ER+ / HER2- metastatic breast cancer. Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor with best-in-class potential.
Our scientific breakthroughs are accelerated through the ways in which we fearlessly support, motivate, and challenge one another. At Olema, we know that when we put people first, our work becomes second to none. If you're ready to join us at the edge of something unstoppable, let's make a profound impact together for our patients, for your career, for what's beyond.
As the Director of Facilities, Laboratory Operations and EHS reporting to the VP of IT, Real Estate and Facilities Lab Operations you will be responsible for the strategic leadership, operational excellence, and long-term planning of Olema's facilities and laboratory environments across multiple sites. In this role you will own the full lifecycle of facilities and lab operations, from day-to-day execution to large-scale initiatives including laboratory buildouts, office and lab relocations. This role will oversee three Olema locations, including BSL2 laboratory environments and corporate office space, and serves as a senior partner to Research, IT, Real Estate, Finance, and Executive Leadership.
This role is based in our San Francisco office and will require 15% travel.
Your work will primarily encompass :
Facilities, Real Estate & Capital Execution
- Lead and execute all facilities operations and physical infrastructure activities across Olema's locations
- Own the execution of Real Estate strategy, including site readiness, lease transitions, expansions, consolidations, and exits
- Lead office and laboratory moves and building relocations, with full accountability for planning, execution, risk management, and stabilization
- Direct laboratory and office buildouts end-to-end, from programming and design through permitting, construction, commissioning, and occupancy
- Execute capital projects in active lab environments while maintaining safety, compliance, and continuity of scientific operations
- Develop and enforce facilities standards, policies, procedures, and SOPs
- Own physical security programs, including access control, badging, alarms, vendor oversight, and incident response
- Control facilities operating and capital budgets, including forecasting, spend management, and cost accountability
- Lead emergency planning and response across all facilities
- Direct shipping and receiving operations, including Hazardous Materials and Dangerous Goods compliance
- Own all workplace services across all locations, including office supplies, beverage and food programs, janitorial services, and waste management, with accountability for vendor performance, cost control, and service quality
Laboratory Operations
Support the research team with all infrastructure needs, including vendor relationships and management, service and maintenance of scientific equipment, hazardous waste management, and cell culture supportMonitor critical systems and provide 24-hour on-call support in case of system failureDevelop and maintain awareness of health and safety issues within the company, ensure compliance with company policies through appropriate training of employees, and manage safety consultants effectively.Manage and Maintain Cryo storage, liquid nitrogen, compressed gas system, emergency generator system, vacuum and compressed air systemsManage critical laboratory systems, including but not limited to HVAC, monitoring, systems and equipment maintenance, to ensure uninterrupted functionality and optimal performanceOversee all aspects of shipping and receiving operations, including inventory management, packaging, and transportation logistics, to facilitate efficient and timely movement of goodsLead and execute laboratory operations to ensure uninterrupted, compliant research supportEnvironmental Health & Safety (EHS) Ownership
Accountable owner of Olema's Environmental Health and Safety programDesign, implement, enforce, and continuously improve EHS policies, procedures, training, and compliance programsLead all regulatory inspections, audits, and agency interactionsOwn hazardous waste permitting, reporting, corrective actions, and compliance documentationEmbed EHS requirements into lab design, construction, moves, and daily operationsDirect EHS consultants and contractors with clear accountability for outcomesMaintain, train and scale EHS programs supporting BSL-2 laboratory environmentsIdeal Candidate Profile :
A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. All employees within our company play a unique and crucial role in our success, both in accomplishing our mission and building a positive company culture. As such, we are looking for someone with the right combination of knowledge, experience, and attributes for this role.
Knowledge
Bachelor's Degree requiredStrategic Facilities Manager (SFM) and Certified Safety Professional (CSP) certifications requiredProven track record of successful facilities leadership experienceExpert-level knowledge of facilities, laboratory operations, and EHS in biotech or life sciencesStrong project management, planning, organization, and time management skillsExperience
Minimum of 10+ years of experience with a minimum of 5 years of facilities management experience, including oversight of lab environmentsCreated and ran an EHS program for a BSL2 Lab a must haveDemonstrated ownership of lab buildouts relocations, and real estate executionHands-on facilities, lab operations, and leadership experience who can move seamlessly between strategic planning and tactical execution, particularly in challenging laboratory settings that require sound judgment, calm decision-making, and rigorous operational disciplineDemonstrated experience working in a demanding and fast-paced lab environment where uptime, safety, compliance, and responsiveness are critical, and where competing priorities and situational ambiguity are the norm rather than the exceptionAttributes
Highly organized with strong attention to detail, clarity, and accuracySolutions-oriented with a meticulous eye for detail and thrives in a fast-paced, problem-solving environmentProactive, self-motivated, and results-oriented with a "bias for action"Collaborative team player who thrives in a cross-functional environmentFlexible and adaptable to evolving business needs and technology trendsExcellent written verbal and interpersonal communication skills and ability to adapt communication styles to varied internal and external partnersThe base pay range for this position is expected to be $210,000 - $220,000 annually, however the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits.