PK/PD Module expert: Translational / Clinical Pharmacology Decision-MakerMercor • Kingsport, Tennessee, US

No longer accepting applications

PK / PD Module expert : Translational / Clinical Pharmacology Decision-Maker

Mercor • Kingsport, Tennessee, US

1 day ago

Job type

Full-time

Remote

Job description

The client is seeking an external expert who brings a

decision-maker’s mindset
— someone who has personally driven translational pharmacology choices under governance and uncertainty.

###

Who we’re looking for

Has owned FIH starting dose, SAD / MAD design, and Phase 2 dose selection for multiple assets. - Participated in governance or review boards, defending dose / exposure rationale in front of senior leadership or regulators. - Demonstrates ability to balance

nonclinical → clinical translation

: tox, PK, PD, potency, and MoA. - Can articulate the

real decision calculus

behind dose selection (safety, pharmacology, speed-to-proof). - Capable of turning narrative judgment into

explicit decision rules and rubrics

for AI training and evaluation. ###

Experience level

~10+ years in major biopharma or biotech (e.g., Lilly, Roche, AbbVie, Amgen, Novartis, GSK, Regeneron, Vertex, Incyte, Gilead) or in specialized translational pharmacology consulting. - Has

personally led

FIH dose and / or SAD / MAD escalation for ≥2–3 assets. - Proven governance experience : IND sign-off, dose justification memos, exposure–response presentations. - CV or track record includes statements like _“led clinical pharmacology strategy and FIH dose selection”_ or _“accountable for exposure–response in Phase 1 / 2.”_ - Avoid pure modeling profiles; the ideal expert has

decision accountability

, not just analytical skill. ###

Expectations

Write “golden” FIH dose rationales and escalation strategies for representative programs. - Encode the

decision heuristics and trade-offs

used by senior translational leaders into structured guidance and rubrics. - Surface

unwritten decision rules

— when and why experienced teams override model-based recommendations.

Inputs given :

Representative drug programs or data packets (GLP tox summaries, PK / PD tables, potency & MoA context). - Target prompts for translational decision-making (e.g., _“Recommend FIH dose and escalation strategy given these data”_).

Expected outputs :

Golden Decision Memos :

exemplar dose justification memos that reflect the level of reasoning and format expected from top-tier translational pharmacologists. -

Decision Rubrics :

scoring guides capturing acceptable vs. unsafe dose rationales, missed edge cases, or failure modes. -

Meta-Layer Commentary :

short narrative explaining unspoken heuristics — how senior teams weigh risk tolerance, potency data, or tox uncertainty.

Create a job alert for this search

Clinical Pharmacology • Kingsport, Tennessee, US

Related jobs

Locum Physician (MD / DO) - Urology in Kingsport, TN

LocumJobsNetwork • Kingsport, TN, US

Full-time

LocumJobsNetwork is working with Curative to find a qualified Urology MD in Kingsport, Tennessee, 37660!.Gastroenterology Locums Physician - Tennessee, 1-2 Weeks a Month. This Gastroenterology assig...Show more

Last updated: 30+ days ago • Promoted

Travel Skilled Nursing Facility (SNF) Physical Therapist

The Good Life MedStaff • Big Stone Gap, VA, US

Full-time

The Good Life MedStaff is seeking a travel Skilled Nursing Facility (SNF) Physical Therapist for a travel job in Big Stone Gap, Virginia. Job Description & Requirements.The Good Life MedStaff Jo...Show more

Last updated: 1 day ago • Promoted

Travel Skilled Nursing Facility (SNF) Physical Therapist

Critical Connection, inc • Big Stone Gap, VA, US

Full-time

Critical Connection, inc is seeking a travel Skilled Nursing Facility (SNF) Physical Therapist for a travel job in Big Stone Gap, Virginia. Job Description & Requirements.PHYSICAL THERAPIST (PT)...Show more

Last updated: 15 days ago • Promoted

Travel Physical Therapist (PT) - $1,820 to $1,994 per week in Big Stone Gap, VA

AMN Healthcare Allied • BIG STONE GAP, VA, US

Full-time

Job Description & Requirements.Physical Therapist - Skilled - (PT - Skilled) .StartDate : 12 / 8 / 2025 Available Shifts : 8 D Pay Rate : $1819. Big Stone Gap, VA, offers a rich cultural experience w...Show more

Last updated: 21 days ago • Promoted

Locum Gastroenterology Physician job in Kingsport, TN - Make $4,000 / day - $4,500 / day

Aya Locums • Kingsport, TN, US

Full-time

Aya Locums has an immediate opening for a locum Gastroenterology job in Kingsport, TN paying $4000 / day- $4500 / day.Shift Coverage : 24 Hour On Call. Shift Schedule : Standard 5, 24-Hour 07 : 00 - 07 : 00....Show more

Last updated: 3 days ago • Promoted

Travel Physical Therapist (PT) - $1,820 to $3,000 per week in Big Stone Gap, VA

CompHealth • Big Stone Gap, VA, US

Full-time

When it comes to finding the perfect locums assignment, sometimes it is all about who you know.CompHealth has been around for a long time and have a vast network of connections to facilities across...Show more

Last updated: 14 days ago • Promoted

Travel Physical Therapist (PT) - $2,022 per week in Big Stone Gap, VA

Triage Staffing LLC • Big Stone Gap, VA, US

Full-time

Travel Rehab : Physical Therapy Big Stone Gap, VA.Location : Big Stone Gap, VA.Shift Details : 0H Days (11 : 49 AM-11 : 49 AM). Length : 13 WEEKS 13 weeks.Apply for specific facility de...Show more

Last updated: 21 days ago • Promoted

Remote PK / PD Module expert : Translational / Clinical Pharmacology Decision-Maker - AI Trainer ($175-$250 per hour)

Mercor • Kingsport, Tennessee, US

Remote

Full-time

The client is seeking an external expert who brings a • •decision-maker’s mindset • • — someone who has personally driven translational pharmacology choices under governance and uncertainty.Who we’re ...Show more

Last updated: 13 hours ago • Promoted • New!

Travel Physical Therapist (PT) - $2,514 per week in Big Stone Gap, VA

AlliedTravelCareers • Big Stone Gap, VA, US

Full-time

AlliedTravelCareers is working with Care Career to find a qualified Physical Therapist (PT) in Big Stone Gap, Virginia, 24219!. Physical therapists work with patients to improve their movement and m...Show more

Last updated: 1 day ago • Promoted

Travel Nurse - RN - MS - Medical Surgical - $2106 / Week

Uniti Med • Norton, VA, US

Full-time

Uniti Med is seeking an experienced Medical Surgical Registered Nurse for an exciting Travel Nursing job in Norton, VA.Shift : Inquire Start Date : ASAP Duration : 13 weeks Pay : $2106 / Week.Uniti Med...Show more

Last updated: 27 days ago • Promoted

Travel Medical-Surgical RN

Premier Medical Staffing Services • Kingsport, TN, US

Permanent

Premier Medical Staffing Services is seeking a travel nurse RN Med Surg for a travel nursing job in Kingsport, Tennessee. Job Description & Requirements.Premier Medical Staffing Job ID #607841.P...Show more

Last updated: 2 days ago • Promoted

Travel Nurse RN - Medical-Surgical - $1,778 per week in Norton, VA

TravelNurseSource • Norton, VA, US

Full-time

TravelNurseSource is working with Coast Medical Service to find a qualified Med / Surg RN in Norton, Virginia, 24273!.Coast Medical Service is a nationwide travel nursing & allied healthcare staf...Show more

Last updated: 14 days ago • Promoted

Remote PK / PD Modeling / Pharmacometrics Lead - AI Trainer ($150-$200 per hour)

Mercor • Kingsport, Tennessee, US

Remote

Part-time

This person complements the client’s “Translational / Clinical Pharmacology Decision-Maker” team by grounding dose selection and exposure–response analysis in • •quantitative structure and parameter...Show more

Last updated: 13 hours ago • Promoted • New!

Travel Physical Therapist

Care Career • Big Stone Gap, VA, US

Full-time

Care Career is seeking a travel Physical Therapist for a travel job in Big Stone Gap, Virginia.Job Description & Requirements. Physical therapists work with patients to improve their movement an...Show more

Last updated: 1 day ago • Promoted

Travel Physical Therapist (PT) - $1,647 to $1,826 per week in Big Stone Gap, VA

AlliedTravelNetwork • Big Stone Gap, VA, US

Full-time

AlliedTravelNetwork is working with LRS Healthcare to find a qualified Physical Therapist (PT) in Big Stone Gap, Virginia, 24219!. Ready to start your next travel adventure? LRS Healthcare offers a ...Show more

Last updated: 21 days ago • Promoted

Locum Physician (MD / DO) - Urology in Kingsport, TN

LocumJobsOnline • Kingsport, TN, US

Full-time

LocumJobsOnline is working with Curative to find a qualified Urology MD in Kingsport, Tennessee, 37660!.Gastroenterology Locums Physician - Tennessee, 1-2 Weeks a Month. This Gastroenterology assign...Show more

Last updated: 30+ days ago • Promoted

Travel Physical Therapist (PT) - $1,647 to $1,826 per week in Big Stone Gap, VA

LRS Healthcare • Big Stone Gap, VA, US

Full-time

Ready to start your next travel adventure? LRS Healthcare offers a full benefits package, 24 / 7 support, and a responsive, traveler-first culture. What are you waiting for? Apply today!.Valid license...Show more

Last updated: 21 days ago • Promoted

Travel Physical Therapist (PT) - $2,514 per week in Big Stone Gap, VA

AlliedTravelNetwork • Big Stone Gap, VA, US

Full-time

AlliedTravelNetwork is working with Care Career to find a qualified Physical Therapist (PT) in Big Stone Gap, Virginia, 24219!. Physical therapists work with patients to improve their movement and m...Show more

Last updated: 1 day ago • Promoted