Director of Clinical Operations (Boston)

Director of Clinical Operations

Location : Boston, MA

Salary : $190,000-$250,000 (USD) + Performance Bonus + Pre-IPO Equity

Company Summary :

Join a next-generation biotech at the intersection of AI and endocrinology. This Boston-based company is reimagining how we discover and develop therapies for complex hormonal and metabolic disorders. With a proprietary platform that integrates machine learning, medicinal chemistry, and translational biology, the team is advancing a pipeline of novel small molecules targeting endocrine pathways with high unmet need. As they prepare to enter the clinic, you'll be the operational force behind their first-in-human trials-building systems, leading execution, and shaping the future of endocrine care.

What You'll Do :

• Own clinical operations strategy and execution for endocrine programs, including rare and chronic metabolic diseases. Drive trials from IND through Phase 2 / 3 with precision and urgency.
• Establish SOPs, select and manage CROs, and implement scalable systems that support rapid trial startup and data integrity.
• Leverage digital tools, AI-enabled trial design, and real-world data to optimize patient recruitment, site selection, and endpoint measurement.
• Collaborate with computational chemists, translational scientists, and regulatory experts to ensure trials are scientifically aligned and operationally sound.
• Hire, mentor, and inspire a nimble clinical operations group that thrives in a fast-paced, high-accountability environment.

What You Bring :

If you or someone you know thrives in ambiguity, love building from scratch, and bring a hands-on, solutions-first approach to every challenge, we'd love to speak with you.