Senior Director, Clinical Operations

Revolution Medicines is a clinical‑stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS‑addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity

The development, management, and execution of the Clinical Development Plan (CDP) for clinical programs which includes clinical trial timeline estimates, budgets, and resource requirements.

Oversight over the execution of clinical trials, including CRO selection and site selection.

Successful planning and deployment of Clinical Operations staff for project and non‑project related tasks; establish clear roles and responsibilities for team members and include opportunities to stretch skills and enable growth.

Line management responsibilities including hiring, performance management, career development and mentorship.

Participate in or lead team meetings and collaborate with other functional groups within the company (e.g., Clinical Development, DMPK, Regulatory, QA, Finance, Legal, etc.) to achieve clinical study goals in accordance with regulations and International Council for Harmonization (ICH) / GCP guidelines.

Required Skills, Experience and Education

BS / MS Degree in a scientific discipline with a minimum of 12 years of clinical operations experience in the pharmaceutical or biotech industry.

Minimum of 7 years project and line management experience.

Extensive experience in leading and managing global phase 1‑3 clinical trials within designated timelines, resources, and budgets.

Experience in working with cooperative group studies and investigator sponsored trials, preferred.

A demonstrable record of strong leadership and teamwork.

Extensive experience in selection of CROs / vendors and management of external resources.

Must have a working knowledge of data management, data review and analysis, and drug safety, pharmacovigilance and other related functions as related to clinical trial conduct.

Strong working knowledge of FDA Regulations, ICH Guidelines and GCPs governing the conduct of clinical trials.

Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high‑energy environment.

Excellent written and verbal communication skills.

Ability to act as an excellent ambassador for Revolution Medicines in interactions with key opinion leaders, scientific advisors, corporate partners and, where necessary, investors.

Demonstrated ability to multi‑task, prioritize options, anticipate challenges, and execute on goals as a member of an interdisciplinary team is extremely important.

Preferred Skills

Experience in oncology clinical trials.

The base pay salary range for this full‑time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job‑related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity / expression, national origin / ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by phone or email. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.

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