Talent.com
(Principal) Proteomics Scientist / Investigator

(Principal) Proteomics Scientist / Investigator

EPM ScientificSan Diego, CA, United States
9 hours ago
Job type
  • Full-time
Job description

About the Role

The client is an innovative early-stage biotech organization focused on accelerating drug development and advancing personalized medicine through multi-omics solutions. Leveraging cutting-edge mass spectrometry technology, advanced computational tools, and comprehensive human health data, the client enables rapid biomarker discovery at scale. This approach provides deeper insights into human biology and aligns therapeutic targets with patient populations to improve treatment precision and outcomes. The team consists of highly collaborative scientists, clinicians, and engineers committed to scientific rigor and transformative innovation.

Position Overview

We are seeking a dynamic Proteomics Principal Investigator to lead complex proteomics initiatives, foster scientific breakthroughs, and strengthen client partnerships. This role requires deep expertise in mass spectrometry-based proteomics, strong leadership capabilities, and proficiency in integrating multi-omics data to deliver actionable insights within a regulated CRO setting. The ideal candidate excels in collaborative environments, mentors high-performing teams, and sets the standard for scientific excellence.

Key Responsibilities

  • Partner with leading experts to promote growth through advanced training and knowledge-sharing.
  • Oversee project execution between the client and internal wet- and dry-lab teams, ensuring timely delivery and resolving challenges as needed.
  • Design research strategies, develop study plans, and prepare comprehensive reports.
  • Analyze mass spectrometry data, review spectra, and identify compounds.
  • Guarantee data integrity and compliance with quality and regulatory standards.
  • Compile findings into presentations and deliverables for stakeholders.
  • Manage multiple projects simultaneously, ensuring timelines and objectives are met.
  • Interpret complex scientific results and stay current with emerging technologies and literature.

Required Experience

  • Minimum 5 years in CRO, pharmaceutical, or biotech environments with hands-on experience in LC-MS / MS platforms (Orbitrap, Q-TOF, timsTOF) and data analysis workflows (DDA, DIA, PRM, MRM / SRM, TMT / iTRAQ, PTM).
  • At least 5 years in a leadership role managing scientific teams and projects.
  • Demonstrated ability to design and execute advanced proteomics experiments (discovery, targeted, PTM analysis).
  • Proven track record in client-facing roles, scientific presentations, and cross-functional collaboration.
  • Qualifications

  • PhD / MD in a relevant discipline (chemistry, biochemistry, biology, pharmacology, or related life sciences) or equivalent experience. BS + 10 years or MS + 5 years relevant experience.
  • Strong background in mass spectrometry-based proteomics and data interpretation.
  • Experience with metabolomics and proteomics methodologies.
  • Skilled in managing multiple priorities, mentoring teams, and delivering results under tight timelines.
  • Ability to communicate complex scientific concepts clearly in both written and verbal formats.
  • Collaborative mindset with experience working alongside multidisciplinary teams.
  • Detail-oriented with a commitment to accuracy and reliability.
  • Up-to-date knowledge of precision medicine advancements.
  • Role Impact

    This is a client-facing leadership position, serving as a strategic partner to laboratory operations. The role involves managing 15+ client programs, contributing to study design, developing project plans, and ensuring seamless communication between clients and internal teams to deliver transformative biological insights across diverse therapeutic areas.

    Create a job alert for this search

    Principal • San Diego, CA, United States

    Related jobs
    • Promoted
    Biochemist

    Biochemist

    TradeJobsWorkforce92191 San Diego, CA, US
    Full-time
    Biochemist Job Duties : Leads development and implementation of biomolecule analysis....Show moreLast updated: 30+ days ago
    • Promoted
    Principal Scientist, Conjugation - Discovery Chemistry

    Principal Scientist, Conjugation - Discovery Chemistry

    ADARx Pharmaceuticals Inc.San Diego, CA, US
    Full-time
    We are seeking a highly motivated and qualified individual to join our Discovery Chemistry Department as a Principal Scientist, Conjugation and work as part of a team to drive success.Ideal candida...Show moreLast updated: 25 days ago
    • Promoted
    Data Scientist (Navy / DoD)

    Data Scientist (Navy / DoD)

    THOR Solutions, LLCSan Diego, CA, United States
    Temporary
    US Navy Ship Anti-Submarine Warfare (ASW) Readiness and Effectiveness Measuring (SHAREM) at Surface and Mine Warfighting Development Center (SMWDC) in. This position is associated with an upcoming c...Show moreLast updated: 30+ days ago
    • Promoted
    Senior Scientist, In Vivo - Cell & Gene Therapy

    Senior Scientist, In Vivo - Cell & Gene Therapy

    PharmaronSan Diego, CA, US
    Full-time
    Senior Scientist, In Vivo - Cell & Gene Therapy.Pharmaron is a global CRO (Contract Research Organization) helping pharma and biotech companies bring new therapies to life.With over 21,000 empl...Show moreLast updated: 30+ days ago
    • Promoted
    Clinical Research Associate

    Clinical Research Associate

    Orso HealthLa Jolla, CA, US
    Full-time
    Orso Health is a leading organization in clinical research, dedicated to advancing healthcare through innovative studies. We are committed to excellence in research and invite you to be part of our ...Show moreLast updated: 4 days ago
    • Promoted
    Project Biologist

    Project Biologist

    Bio-Studies Inc.San Diego County, CA, US
    Full-time
    Bio-Studies is a growing natural resources consulting firm in Southern California providing quality natural resources consulting services to a diversity of clientele.Our team of biologists off...Show moreLast updated: 4 days ago
    • Promoted
    Data Scientist VI

    Data Scientist VI

    Kaiser PermanenteSan Diego, CA, United States
    Full-time
    This senior individual contributor is primarily responsible for overseeing the design and development of data pipelines and automation for data acquisition and ingestion of raw data from multiple d...Show moreLast updated: 4 days ago
    • Promoted
    Senior Scientist I, Conjugation

    Senior Scientist I, Conjugation

    ADARx Pharmaceuticals Inc.San Diego, CA, US
    Full-time
    We are seeking a highly motivated and qualified individual to join our Conjugation-Discovery Chemistry Department as a Senior Scientist I and work as part of a team to drive success.Ideal candidate...Show moreLast updated: 30+ days ago
    • Promoted
    Epidemiologist

    Epidemiologist

    TradeJobsWorkForce92106 San Diego, CA, US
    Full-time
    Plan and direct studies of public health problems to find ways to prevent and treat them if they arise Collect and analyze data—through observations, interviews, and surveys, and by using samples o...Show moreLast updated: 30+ days ago
    • Promoted
    Scientist I, Neuroscience

    Scientist I, Neuroscience

    ADARx Pharmaceuticals Inc.San Diego, CA, US
    Full-time
    We are seeking a highly motivated and qualified individual to join our Discovery Biology Department as a Senior Scientist I and work as part of a team to drive success. The Senior Scientist I will s...Show moreLast updated: 30+ days ago
    • Promoted
    SENIOR PROSPECT RESEARCHER

    SENIOR PROSPECT RESEARCHER

    Scripps ResearchLa Jolla, CA, US
    Full-time
    Scripps Research is a nonprofit biomedical institute ranked as one of the most influential in the world for its impact on innovation. We are celebrating our 100-year legacy.This significant mileston...Show moreLast updated: 30+ days ago
    • Promoted
    Neurobiologist

    Neurobiologist

    TradeJobsWorkForce92131 San Diego, CA, US
    Full-time
    Neuorbiologist Job Duties : Completes neurobiological studies by conducting tests, examina...Show moreLast updated: 30+ days ago
    • Promoted
    Principal Scientist, Protein Sciences

    Principal Scientist, Protein Sciences

    CalifesciencesSan Diego, CA, United States
    Full-time
    Artificial Intelligence ("AI") for the development of hard-to-drug precision antibodies in the cardiometabolic and obesity space. Our core mission is to harness the potential of AI and machine learn...Show moreLast updated: 4 days ago
    • Promoted
    Principal Data Scientist - Remote - 2308370

    Principal Data Scientist - Remote - 2308370

    UnitedHealth GroupSan Diego, CA, United States
    Remote
    Full-time
    Optum is a global organization that delivers care, aided by technology to help millions of people live healthier lives.The work you do with our team will directly improve health outcomes by connect...Show moreLast updated: 30+ days ago
    • Promoted
    • New!
    Senior Scientist

    Senior Scientist

    Net2Source (N2S)San Diego, CA, United States
    Full-time
    Recognized for 300% growth in the past three years, we operate in 32 countries with a global team of 5,500+.Our mission? To bridge the talent gap with precision—Right Talent.Job Title : Scientist I,...Show moreLast updated: 3 hours ago
    • Promoted
    Biochemist

    Biochemist

    TradeJobsWorkForce92106 San Diego, CA, US
    Full-time
    Biochemist Job Duties : Leads development and implementation of biomolecule analysis.De...Show moreLast updated: 30+ days ago
    • Promoted
    Cosmotologist

    Cosmotologist

    TradeJobsWorkForce92196 San Diego, CA, US
    Full-time
    Cosmotologist Job Duties : Maintains supplies by checking stock; anticipating needs; placing o...Show moreLast updated: 30+ days ago
    • Promoted
    • New!
    Senior Scientist, Cardiac Biology Transcriptomics

    Senior Scientist, Cardiac Biology Transcriptomics

    HAYA TherapeuticsSan Diego, CA, United States
    Full-time
    At HAYA Therapeutics, we are revolutionizing RNA-guided genome-targeting therapies to treat fibrosis, heart failure, and other serious diseases associated with aging. Our innovative platform leverag...Show moreLast updated: 3 hours ago
    • Promoted
    Process Chemistry Senior Principal Scientist

    Process Chemistry Senior Principal Scientist

    Vertex PharmaceuticalsSan Diego, CA, United States
    Full-time
    The successful candidate will possess a deep knowledge of process chemistry skills for the development of synthetic routes, with knowledge and experience in early and mid to late-phase development ...Show moreLast updated: 30+ days ago
    • Promoted
    • New!
    Local Contract Nuclear Medicine Technologist - $89 per hour

    Local Contract Nuclear Medicine Technologist - $89 per hour

    Stability HealthcareLa Jolla, CA, United States
    Full-time
    Stability Healthcare is seeking a local contract Nuclear Medicine Technologist for a local contract job in La Jolla, California. Job Description & Requirements.Stability Healthcare is looking for a ...Show moreLast updated: 6 hours ago