(Senior) Director, Project Team Lead - Clinical

Join to apply for the (Senior) Director, Project Team Lead - Clinical role at insitro

Join to apply for the (Senior) Director, Project Team Lead - Clinical role at insitro

The Opportunity

insitro is using machine learning to yield new, clinically actionable insights into critical unmet needs for patients. We aim to "go fast and improve things" across the entire drug development process from platform to pipeline to patients and back again.

The (Senior) Director, Project Team Lead (PTL, also called Asset Team Lead [ATL]) for Clinical Development is an opportunity to directly improve patients' lives by leading cross functional drug development teams from preclinical development candidate (DC) nomination through Phase 1-2 clinical development including proof-of-mechanism (POM) and proof-of-concept (POC). The PTL is accountable for an end-to-end, cross-functional, and effective integration of the therapeutic molecule strategy, timeline, and risk mitigation.

We are devoted to the effort to make clinical trials more helpful for patients and for drug developers. We believe that by focusing on what's best for patients, we can do what's best for drug development at the same time.

You will be at the forefront of designing and implementing innovative, accelerated approaches, and you will have the opportunity to utilize insitro's machine learning expertise to achieve drug development and clinical trial excellence.

You will report directly to the Chief Medical Officer. This role can be either onsite (3 days per week) in our South San Francisco office or hybrid (~1 week per month) in our office. Additional travel may be needed to relevant medical and health authorities.

This is an excellent opportunity for a seasoned PTL who is passionate about using their skills and experience to accelerate the drug development process and bring better drugs to the patients who can benefit most.

Responsibilities

In collaboration with cross-functional teams and working closely with Project and Portfolio Management :

• Cross-functional asset / program leadership is the key part of this role
• Develop and implement clinical program plans
• Develop vision, strategy, and an end-to-end product plan that accounts for early uncertainties in first-in-human clinical development, define prospective, quantifiable endpoints for effective Go No Go decisions, enable the generation of a clinical data package that could support future registrational trial development and commercialization, and ensure there are adequate resources and technical expertise to meet strategic objectives
• Identify and manage critical path activities and resources
• Identify and manage interdependencies and hand-offs
• Identify, classify, proactively mitigate, and document (as appropriate) potential risks and roadblocks, including likelihoods, severities, and key mitigations
• Lead contingency planning
• Capture and communicate progress; escalate potential delays with proposed solutions
• Direct clinical programs through insitro governance to ensure that :
• Key drug development functions including preclinical, clinical, technical development / CMC and computational achieve strategic and operational alignment
• Programs have adequate resources and technical expertise to meet strategic objectives
• Issues are raised, discussed, and resolved in a timely manner
• Program / project teams receive insitro Governance decisions in a timely manner
• Programs adhere to agreed-upon scope, timelines, resources, and budget
• Communication and Culture
• Accountable for clear and timely communication about the program throughout insitro such as via : agendas, minutes, all-hands and other communication methods
• Responsible for facilitating Core Team meetings and working with Sub-team Leaders to ensure sub-teams and Core Teams are working in alignment on strategic and operational topics.
• Present project updates, strategic issues, options, and recommendations to the insitro Governance Committees
• Ensure clear and effective communication by each asset / project team by overseeing / reviewing presentations and documents to ensure clarity and effectiveness
• Contribute to team culture and positively influence team environment that encourages authentic, clear communication and a "get stuff done" mentality

About You

Compensation & Benefits At Insitro

Our target starting salary for successful US-based applicants for this role is $210,000 - $275,000. To determine starting pay, we consider multiple job-related factors including a candidate's skills, education and experience, market demand, business needs, and internal parity. We may also adjust this range in the future based on market data.

This role is eligible for participation in our Annual Performance Bonus Plan (based on company targets by role level and annual company performance) and our Equity Incentive Plan, subject to the terms of those plans and associated policies.

In addition, insitro also provides our employees :

insitro is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

We believe diversity, equity, and inclusion need to be at the foundation of our culture. We work hard to bring together diverse teams–grounded in a wide range of expertise and life experiences–and work even harder to ensure those teams thrive in inclusive, growth-oriented environments supported by equitable company and team practices. All candidates can expect equitable treatment, respect, and fairness throughout the interview process.

About Insitro

insitro is a drug discovery and development company using machine learning (ML) and data at scale to decode biology for transformative medicines. At the core of insitro’s approach is the convergence of in-house generated multi-modal cellular data and high-content phenotypic human cohort data. We rely on these data to develop ML-driven, predictive disease models that uncover underlying biologic state and elucidate critical drivers of disease. These powerful models rely on extensive biological and computational infrastructure and allow insitro to advance novel targets and patient biomarkers, design therapeutics and inform clinical strategy. insitro is advancing a wholly owned and partnered pipeline of insights and therapeutics in neuroscience, oncology and metabolism. Since launching in 2018, insitro has raised over $700 million from top tech, biotech and crossover investors, and from collaborations with pharmaceutical partners. For more information on insitro, please visit www.insitro.com.

Seniority level

Seniority level

Mid-Senior level

Employment type

Employment type

Full-time

Job function

Job function

Consulting, Information Technology, and Sales

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