Team Lead, In vivo Pharmacology, Disease Mechanism Research - Now Hiring!

Team Lead, In vivo Pharmacology, Disease Mechanism Research

Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians.  If you want to be part of this exciting work, you belong at Astellas!

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at www.astellas.com .

Purpose and Scope :

The Disease Mechanism Research team at Astellas West Coast Innovation Center is seeking an exceptional leader to drive in vivo pharmacology efforts to support the Astellas oncology pipeline.  The ideal candidate should demonstrate deep understanding of cancer biology and immune-oncology, and lead pre-clinical in vivo research focused on understanding the mechanism of action of Astellas’ Cancer Biology modalities. A successful candidate will direct a team of in vivo pharmacology scientists to increase the probability of clinical success for oncology therapies. This position will be located on site in South San Francisco.

Essential Job Responsibilities :

• Lead a team of in vivo pharmacology scientists to generate high quality data to support Astellas’ Cancer Biology pipeline
• Serve as an expert in oncology and immune-oncology in vivo model development
• Design, plan, and supervise anti-tumor efficacy and PK / PD studies in mice
• Lead the efforts to address MoA and safety of novel therapeutics in vivo
• Act as a representative of in vivo pharmacology team in scientific discussions with multi-disciplinary teams and senior leadership.
• Interface with colleagues from different therapeutic focus areas at Astellas
• Proactively seek out, recognize, and assess novel biology and technologies in Oncology / Immuno-Oncology space