Principal Scientist, Translational Medicine

Principal Scientist, Translational Medicine

Umoja Biopharma is a game-changing biotech start-up with locations in Seattle, WA and Louisville, CO, focused on transforming the treatment of cancer with a novel integrated immunotherapy platform. Our vision is to develop off-the-shelf therapies capable of treating any tumor, any time. We are committed to Diversity, Equity, and Inclusion and invite applications from enthusiastic individuals who share this commitment.

Umoja Biopharma – Your Body. Your Hope. Your Cure.

Position Summary

The Translational Medicine team seeks a highly motivated Principal Scientist to advance investigational products through clinical phase studies and lead efforts to elucidate mechanisms of response, relapse, and resistance. The role includes leading translational medicine efforts on designated clinical studies and supporting trial objectives related to safety, pharmacokinetics (PK) / pharmacodynamics (PD), immunogenicity, disease biology, and exploratory biomarker identification. The position reports to the Director of Translational Medicine and is responsible for designing and executing translational strategies, driving internal and external bioanalytical assay development, and integrating clinical insights into the pipeline. The role involves correlative studies, hypothesis-driven investigations, and reverse translation of clinical phase discoveries back into the pipeline, with a mix of hands-on lab work and collaboration with external partners and vendors.

This is a great opportunity to contribute to a startup biotechnology company and help develop the next generation of cancer immunotherapies with potential for greater responsibility and career growth.

Core Accountabilities

• Serve as translational study lead for designated clinical studies, collaborating with clinical, regulatory, and research teams.
• Drive assay development and validation for clinical biospecimen testing (hands-on and oversight).
• Interpret complex data sets and translate findings into actionable insights for pipeline advancement.
• Manage external collaborations and vendor relationships for assay implementation and sample analysis.
• Contribute to cross-program strategic planning within the Translational Medicine group.
• Maintain complete laboratory records in line with applicable guidance and SOPs.
• Prepare technical data reports and presentations.

The Successful Candidate Will Have

Preferred Qualifications

Physical Requirements

Salary Range

$157,250 - $194,250

Benefits

Umoja Biopharma offers medical, dental, and vision plans. 401k with a 100% match up to 4% deferral, generous Paid Time Off, commuter benefits, and a cell phone stipend. For full details, see the Benefits section of the website.

Employment details

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