Executive Director, Biologics Drug Substance Manufacturing Sciences & Technology

Executive Director, Biologics Drug Substance, Manufacturing Sciences & Technology

Location : Devens, Massachusetts

At Bristol Myers Squibb, we are inspired by a single vision transforming patients' lives through science. In oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Position Summary

The Head of Biologics Drug Substance Manufacturing Sciences & Technology is responsible for scientific and technical oversight of Biologics manufacturing processes from full scale process validation through commercialization and life cycle management for BMS' internal and external global network for biologics drug substance.

Additional Position Details

Bristol Myers Squibb is seeking a key leader in our biologics technology organization. The role connects Process Development and Manufacturing and ensures rapid commercialization of robust, compliant processes and effective lifecycle management. With direct accountability for teams of scientists and engineers on three sites, the role is a critical enabler of our pipeline success.

The Biologics MS&T leader will work in close collaboration with Biologics Process Development teams and Manufacturing sites in Devens, MA and Cruiserath, Dublin Ireland in addition to a network of external manufacturers. The person has direct responsibility for a team of scientists to support a growing biologics portfolio, and all Manufacturing Technology teams in plants will report to this position. This position is located in Devens MA.

In collaboration with Biologics Process Development, the jobholder is responsible for providing input on process design, scale-up and technology transfer. The role also ensures effective development of process control strategies and specifications for manufacturing during commercialization at scale. In addition, the jobholder will lead the lifecycle management of the drug substances processes for all approved biological products and will be the lead technical representative to global regulatory agencies for these products. The jobholder will chair the Biologics Drug Substance technology governance team.

Key Responsibilities

• Develop and execute the MS&T strategy aligned with organizational goals and regulatory requirements. Oversee cross-functional initiatives to drive innovation, process optimization, and continuous improvement in manufacturing operations.
• Oversee the commercialization, validation, and implementation of new manufacturing technologies and processes
• Ensure robust technical support for commercial manufacturing, including troubleshooting and process improvements together with investigations and root cause analyses for manufacturing deviations, implementing corrective and preventive actions.
• Build, lead, and mentor a high-performing MS&T team, fostering a culture of collaboration, accountability, and professional growth. Set clear objectives, manage performance, and support career development for team members.
• Collaborate with Process Development, Quality, Regulatory, and Operations to support product development, tech transfer, and life-cycle management.
• Ensure all MS&T activities comply with global regulatory standards (e.g. FDA, EMA) and internal quality systems.
• Champion the adoption of new technologies, digital tools, and best practices to enhance manufacturing efficiency and product quality. Drive a culture of continuous improvement through data-driven decision-making and process optimization.
• Develop and manage MS&T DS budget, ensuring efficient use of resources and alignment with business priorities.

Qualifications & Experience

Ph.D. and / or Masters Degree in pharmaceutical or related sciences with 20+ years of experience in pharmaceutical development and a solid record of achievement in roles of increasing responsibility.

In-depth knowledge and understanding of biologics drug development process, and CMC related FDA and international regulations. Able to anticipate industry trends and emerging issues.

Demonstrated ability to develop and execute strategy to bring maximum value to the organization

Compensation Overview : $270,870 - $328,230

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following : Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as "Transforming patients' lives through science ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.