Associate Director, Statistical Data Scientist

Associate Director, Statistical Data Scientist

Join to apply for the Associate Director, Statistical Data Scientist role at Praxis Precision Medicines, Inc.

Location : This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

Opportunity : Praxis is seeking an Associate Director, Statistical Data Scientist to lead and execute the development, validation and automation of analytical pipelines and statistical models that support metadata-driven clinical data processing, reporting, and regulatory submissions. This is a hands‑on technical leadership role, ideal for a senior data scientist or statistical programmer who enjoys coding, problem‑solving, and working cross‑functionally to bring rigor, reproducibility, and automation to clinical reporting workflows. You will contribute directly to R / Python development while also setting technical standards, mentoring peers, and ensuring readiness for R‑based regulatory submissions.

Primary Responsibilities :

• Lead the design, development, and validation of R / Python code to automate generation of analytical datasets and TLFs within a metadata-driven pipeline.
• Translate SAPs and metadata specifications (YAML / CSV) into executable and reproducible code.
• Build and validate R packages and data science tools supporting both exploratory and confirmatory analyses, ensuring full traceability and audit readiness.
• Implement and validate statistical models (e.g., MMRM, ANCOVA, logistic regression) using R packages such as mmrm, emmeans.
• Collaborate with IT to integrate data science and statistical programming workflows within Databricks and CI / CD pipelines for continuous validation and reproducibility.
• Collaborate across programming, biostatistics, and data standards functions to ensure dataset definitions, derivations, and metadata align with controlled standards.
• Conduct peer code reviews, unit testing, and automated validation; ensuring deliverables meet submission‑quality and reproducibility standards.
• Mentor and guide team members in best practices for programming, validation, and automation.

Qualifications And Key Success Factors :

Compensation & Benefits : At Praxis, we provide a world‑class benefits package to help you thrive. This includes 99% of the premium paid for medical, dental, and vision plans. We also provide company‑paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. We match dollar‑for‑dollar up to 6% on eligible 401(k) contributions, offer long‑term stock incentives and ESPP, provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company‑wide shutdowns. The annualized base salary compensation for this role is $178,000 USD – $198,000 USD.

Company Overview : Praxis Precision Medicines is a clinical‑stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high‑impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust , Ownership , Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.

Diversity, Equity & Inclusion : Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal‑opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.

Job Scam Alert : Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com.

Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.

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