Global Chief Medical Officer

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.

Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.

Legend Biotech is seeking a Global Chief Medical Officer as part of the Clinical Development team based in Somerset, NJ.

Role Overview

Legend Biotech is a global, integrated cell therapy company dedicated to discovering, developing, and manufacturing transformative therapies for patients with cancer, autoimmune, and other serious diseases. The company has a vision of harnessing the power of the immune system to create durable and potentially curative treatments. By combining deep scientific expertise with advanced manufacturing and global execution capabilities, Legend Biotech aims to change the way the world treats disease and to make cutting-edge cell therapies broadly accessible to patients.

Legend Biotech is at the forefront of cell therapy research and development. In pursuit of cure, the company is leveraging its integrated autologous, allogeneic and in vivo cell therapy platforms to design and deliver therapies that can reprogram immune cells to precisely target and eliminate the root cause of diseases, including cancers and autoimmune diseases.

Legend Biotech is recruiting an accomplished drug developer and a visionary organization / business leader as Global Chief Medical Officer (CMO) who will serve as the senior clinical development leader for our ongoing clinical programs and teams in both the United States and China. This role is pivotal in overseeing the global clinical development strategy, ensuring the safety, efficacy, and regulatory compliance of the company's innovative therapies, and shaping the clinical vision for the company's pipeline.

Reporting to President of Research and Development, the Global CMO will work closely with the executive leadership team, regulatory authorities, and key external stakeholders to lead the clinical development program from pre-clinical stages through to post-market activities. Additionally, the Global CMO will act as a strategic thought leader in the field of cell and gene therapy and provide clinical expertise in the design, execution, and interpretation of clinical trials, regulatory submissions, and product commercialization.

This position offers a unique opportunity to join a growing and innovative company at the forefront of cell and gene therapy, where the Global CMO will have the opportunity to make a profound impact on the future of medicine and improve patient outcomes globally.

Key Responsibilities

• Clinical Strategy & Leadership :

Lead the global clinical development strategy and execution for the company's pipeline, ensuring alignment with corporate goals, market needs, and scientific advancements.

Build and lead a high-performing, cross-functional clinical development team across multiple geographies, fostering a culture of collaboration, excellence, and scientific rigor.

Ensure the company's clinical programs are in compliance with regulatory requirements and industry standards (GxP, ICH, etc.).

Oversee the design, conduct, and interpretation of clinical trials, ensuring high-quality data collection, monitoring, and reporting.

Be a thought leader in cell and gene therapy, providing clinical insights into scientific developments, competitive landscapes, and emerging technologies.

Collaborate with the Commercial and Medical Affairs leadership teams to inform product launch strategies, market access, and post-marketing activities.

Requirements

#Li-ML1

#Li-Hybrid

The anticipated base pay range is

$434,828-$570,710 USD

Benefits

We are committed to creating a workplace where employees can thrive - both professionally and personally. To attract and retain top talent in a highly competitive industry, we offer a best-in-class benefits package that supports well-being, financial stability, and long-term career growth. Our offerings are designed to meet the diverse needs of our team members and their families, ensuring they feel valued and supported every step of the way. Highlights include medical, dental, and vision insurance as well as a 401(k)-retirement plan with company match that vest fully on day one. Equity and stock options are available to employees in eligible roles, we offer eight weeks of paid parental leave after just three months of employment, and a paid time off policy that includes 15 vacation days, 5 personal days, 5 sick days, 11 U.S. national holidays, and 3 floating holidays. Additional benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs - demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.

EEO Statement

Legend Biotech is a proud equal opportunity / affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is Legend's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic / civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by applicable law.

Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. Legend may adjust base salary or other discretionary compensation at any time based on individual, team, performance, or market conditions.

Legend Biotech maintains a drug-free workplace.