Vice President, Medical Safety Science

Job Description

Job Description

Position Summary :

Apellis Drug Safety and Pharmacovigilance is responsible for all aspects of patient safety including single case and aggregate safety monitoring, safety reporting, benefit-risk assessment, risk management planning and strategy, execution of certain post-marketing commitments, and compliance with global regulatory requirements. Reporting to the Head of Drug Safety and Pharmacovigilance, the Vice President, Medical Safety Science serves as a senior leader accountable for the strategic direction, operational excellence, and organizational leadership of the Medical Safety Science function. This individual will lead a team of Safety Physicians and PV Scientists and serve as a key decision-maker across the company's pipeline and marketed products. The ideal candidate brings deep clinical knowledge, broad pharmacovigilance expertise, and strong executive presence, and will play a critical role in shaping the company's safety strategy at the highest levels, global regulatory interactions, portfolio governance, and long-term planning.

Preferred job location : Waltham, MA. Remote candidates will be considered on a case-by-case basis or relocation may be provided.

Key Responsibilities Include :

• Enterprise Safety Leadership

Define and execute the vision, strategy, and roadmap for Medical Safety Science across all therapeutic areas and lifecycle stages.

Oversee benefit-risk strategies and signal management activities across the global portfolio, including early development, pivotal studies, post-marketing, and real-world evidence.

Lead global safety input into interactions with health authorities, including FDA, EMA, and PMDA.

Build, mentor, and lead a high-performing organization, including physicians, PV scientists, and cross-functional collaborators.

Oversee the development and execution of safety processes, standards, and technologies to improve efficiency, scalability, and scientific quality.

Lead safety due diligence and risk assessment in partnership with Business Development, Corporate Strategy, and Legal.

Education, Registration & Certification :

Experience :

Physical Demands and Work Environment :

This is largely a sedentary role; however, some filing is required. This would require the ability to lift files, open filing cabinets and bend or stand on a stool as necessary. This job operates in a professional office environment and routinely uses standard office equipment such as computers, phones, photocopiers, filing cabinets and fax machines.

Travel Requirements :

Benefits and Perks :

Base salary for this role will consider multiple factors, including but not limited to, candidate qualifications, relevant expertise, specialized skills, and industry experience in complement-targeted therapies.

The targeted base salary range for this position is $337,000 - $506,000 per year. This range represents the base salary only and reflects Apellis' commitment to competitive compensation within the biopharmaceutical industry. The final salary offered may vary based on individual qualifications, business needs, and current market conditions.

Apellis offers a comprehensive benefits package, including a 401(k) plan with company match, inclusive family building benefits, flexible time off, summer and winter shutdowns, paid family leave, disability and life insurance, and more! Visit https : / / apellis.com / careers / to learn more.

Company Background :

Apellis Pharmaceuticals, Inc. is a global biopharmaceutical company that combines courageous science and compassion to develop life-changing therapies for some of the most challenging diseases patients face. We ushered in the first new class of complement medicine in 15 years and now have two approved medicines targeting C3. These include the first and only therapy for geographic atrophy, a leading cause of blindness around the world. With nearly a dozen clinical and pre-clinical programs underway, we believe we have only begun to unlock the potential of targeting C3 across many serious diseases.

For more information, please visit http : / / apellis.com or follow us on Twitter and LinkedIn

EEO Statement :

Apellis is an equal opportunity employer and complies with all applicable federal, state and local fair employment practices laws. Apellis strictly prohibits and does not tolerate discrimination against employees, applicants or any other covered persons because of race, color, religion, creed, national origin or ancestry, ethnicity, sex (including pregnancy), gender (including gender nonconformity and status as a transgender or transsexual individual), age, physical or mental disability, citizenship, past, current or prospective service in the uniformed services, genetic information, marital status, AIDS / HIV status, smoker / nonsmoker, and occupational pneumoconiosis or any other characteristic protected under applicable federal, state or local law.

For San Francisco postings : Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.

Other Duties :

Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.