Contract Associate Scientist, CMC

Overview

Lexeo Therapeutics is seeking a talented and motivated Contract Associate Scientist to join our CMC team in New York City. This position will play a key role in developing and executing potency assays that support our gene therapy programs. The ideal candidate will be responsible for performing in vitro cell culture, AAV transduction, and analytical assays, ensuring high-quality, reproducible data to support assay validation, qualification, and release. You will also organize, interpret, and summarize experimental data to inform ongoing development activities. This is an on-site position that requires close collaboration with the Analytical Development team and other cross-functional groups within CMC.

Responsibilities

• Perform hands-on experiments in an internal in vitro laboratory, including routine tissue culture and assay execution
• Generate high-quality, reproducible data from cell-based assays; analyze, interpret, and communicate results effectively
• Maintain detailed and accurate laboratory records in compliance with company policies and regulatory standards
• Prepare technical reports and documentation to support assay validation and analytical deliverables
• Collaborate and communicate effectively with team members across CMC and other functional areas
• Ensure adherence to laboratory safety protocols and contribute to maintaining an organized and efficient lab environment

Required Skills & Qualifications

About Lexeo

LEXEO Therapeutics is a New York City-based, clinical-stage gene therapy company focused on addressing some of the most devastating genetically defined cardiovascular and central nervous system diseases affecting both larger-rare and prevalent patient populations. LEXEO's foundational science stems from partnerships and exclusive licenses with leading academic laboratories at Weill Cornell Medicine and the University of California, San Diego. LEXEO is advancing a deep and diverse pipeline of AAV-based gene therapy candidates in rare cardiovascular diseases and APOE4-associated Alzheimer's disease and is led by pioneers and experts with decades of collective experience in genetic medicines, rare disease drug development, manufacturing, and commercialization

This role is expected to be onsite at our NYC headquarters 5 days / week.

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