PK/PD Module expert: Translational / Clinical Pharmacology Decision-MakerMercor • Casa Grande, Arizona, US
No longer accepting applications
PK / PD Module expert : Translational / Clinical Pharmacology Decision-Maker
Mercor • Casa Grande, Arizona, US
1 day ago
Job type
- Full-time
- Remote
Job descriptionWho we’re looking for Has owned FIH starting dose, SAD / MAD design, and Phase 2 dose selection for multiple assets. - Participated in governance or review boards, defending dose / exposure rationale in front of senior leadership or regulators. - Demonstrates ability to balance nonclinical → clinical translation : tox, PK, PD, potency, and MoA. - Can articulate the real decision calculus behind dose selection (safety, pharmacology, speed-to-proof). - Capable of turning narrative judgment into explicit decision rules and rubrics for AI training and evaluation. ### Experience level ~10+ years in major biopharma or biotech (e.g., Lilly, Roche, AbbVie, Amgen, Novartis, GSK, Regeneron, Vertex, Incyte, Gilead) or in specialized translational pharmacology consulting. - Has personally led FIH dose and / or SAD / MAD escalation for ≥2–3 assets. - Proven governance experience : IND sign-off, dose justification memos, exposure–response presentations. - CV or track record includes statements like _“led clinical pharmacology strategy and FIH dose selection”_ or _“accountable for exposure–response in Phase 1 / 2.”_ - Avoid pure modeling profiles; the ideal expert has decision accountability , not just analytical skill. ### Expectations Write “golden” FIH dose rationales and escalation strategies for representative programs. - Encode the decision heuristics and trade-offs used by senior translational leaders into structured guidance and rubrics. - Surface unwritten decision rules — when and why experienced teams override model-based recommendations. Inputs given : Representative drug programs or data packets (GLP tox summaries, PK / PD tables, potency & MoA context). - Target prompts for translational decision-making (e.g., _“Recommend FIH dose and escalation strategy given these data”_). Expected outputs : Golden Decision Memos : exemplar dose justification memos that reflect the level of reasoning and format expected from top-tier translational pharmacologists. - Decision Rubrics : scoring guides capturing acceptable vs. unsafe dose rationales, missed edge cases, or failure modes. - Meta-Layer Commentary : short narrative explaining unspoken heuristics — how senior teams weigh risk tolerance, potency data, or tox uncertainty.
The client is seeking an external expert who brings a
- decision-maker’s mindset
- — someone who has personally driven translational pharmacology choices under governance and uncertainty.
###
Create a job alert for this search
Clinical Pharmacology • Casa Grande, Arizona, US
Related jobs
PAs, NPs) following them around the ED to document patient visits into the electronic medical record system as everything occurs.
Essential Scribe is currently hiring those looking for.In this posit...Show more
Hello,I work with a plasma donation center in Pocatello, ID.We have an open position for a Medical Director (MD or DO) to join us 4 hours a week.
No specialty or experience required.Must be within 5...Show more
Join us in shaping the future of health care.The work is rewarding as we see measurable improvement in our patients.From the time of admission, when they are experiencing a mental health crisis, th...Show more
Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives wi...Show more
Client Services / Revenue Cycle Management.The Client Success Specialist – Healthcare RCM is responsible for ensuring healthcare clients achieve optimal outcomes through our revenue cycle man...Show more
Recently named one of Arizona's Top Workplaces, Arizona Arthritis & Rheumatology Associates, P.Rheumatology practice in the United States.
The practice has over 60 providers, 15 sites and over 300 e...Show more
Looking to be part of something more meaningful? At HonorHealth, you'll be part of a team, creating a multi-dimensional care experience for our patients.
You'll have opportunities to make a differen...Show more
Mon-Fri 8am-5pm OR Tues-Fri 4 / 10's.A Physician provides health care services to patients under the direction and responsible supervision of the Medical Director.
Under the general supervision of the...Show more
THE ARMY HEALTH CARE ADVANTAGE As a member of the Army health care team, you’ll receive benefits that you won’t be able to get in a civilian career.
Challenging Work Feel inspired with great case di...Show more
Join our group of passionate advocates on our mission to improve the lives of youth! Rite of Passage is hiring for a Med Tech / Medical Assistant at Canyon State Academy in Queen Creek, Arizona ✨ Pay...Show more
Who is Nest Health? As the first value-based care provider built for families, Nest is on a mission to make comprehensive medical, behavioral, and social care radically accessible to America's high...Show more
We are seeking a Medical Director to lead our\npractice at Brown Road Animal Clinic located in the heart of\nMesa.We have been dedicated to providing exceptional.Our recently renovat...Show more
Find your Voice, Passion, & Purpose.We are proud to offer new base pay rates starting at $22.This position will coordinate the efforts of the site surgical pathology assistants and assist the AP Pr...Show more
LocumJobsNetwork is working with Wellhart, LLC to find a qualified Psychiatry MD in Eloy, Arizona, 85131!.We are seeking an experienced Psychiatrist for a 10-week locum tenens assignment in Arizona...Show more
LocumJobsOnline is working with Wellhart, LLC to find a qualified Psychiatry MD in Eloy, Arizona, 85131!.We are seeking an experienced Psychiatrist for a 10-week locum tenens assignment in Arizona,...Show more
TRS Healthcare is seeking an experienced Surgical Tech - CVOR for an exciting Travel Allied job in Mesa, AZ.Shift : 3x12 hr days Start Date : 12 / 22 / 2025 Duration : 13 weeks Pay : $2085.TRS Healthcare i...Show more
The Technical Director is responsible for leading all scientific, technical, and innovation functions for a next generation contractor manufacturer specializing in clean, high-performance personal ...Show more
Revitalize Lives Through Movement : Become a Part of Our Inpatient Physical Therapy Team in Mesa.Imagine a daily routine where each step you take helps someone stand tall after an operation, reclaim...Show more
Medical Scribe – Clinic (Mon–Fri)
Essential Scribe • Gilbert, AZ, USA
Full-time
Quick Apply
Last updated: 30+ days ago
Physician / Emergency Medicine / Idaho / Locum tenens / Part-Time Medical Director for Pocatello Job
Samuel Contract Staffing LLC • Gilbert, AZ, US
Part-time
Last updated: 30+ days ago • Promoted
Clinical Resource Leaders
Valleywise Health System • Mesa, AZ, United States
Full-time
Last updated: 4 days ago • Promoted
Innovation Cup 2026 - Team Drug Discovery (all genders)
Merck KGaA • Mesa, AZ, United States
Full-time
Last updated: 17 days ago • Promoted
RCM Client Success Specialist
Altea Healthcare • Gilbert, AZ, US
Full-time
Last updated: 23 days ago • Promoted
Advanced Practice Clinician
Arizona Arthritis & Rheumatology Associates • Mesa, AZ, United States
Full-time
Last updated: 30+ days ago • Promoted
CSPD Tech - FT Days
HonorHealth • Mesa, AZ, United States
Full-time +1
Last updated: 2 days ago • Promoted
PHYSICIAN FAMILY PRACTICE
Sun Life Health • Casa Grande, AZ, United States
Full-time
Last updated: 30+ days ago • Promoted
Active Entomologist
US Army • Apache Junction, AZ, United States
Full-time
Last updated: 30+ days ago • Promoted
Med Tech
Rite of Passage • Queen Creek, AZ, United States
Full-time
Last updated: 4 days ago • Promoted
Advanced Practice Provider (APP) Pod Leader
Nest Health • Arizona City, AZ, United States
Full-time
Last updated: 5 hours ago • Promoted • New!
Medical Director
National Veterinary Associates • Mesa, AZ, US
Full-time
Last updated: 30+ days ago • Promoted
Surgical Pathology Lead - Banner Gateway
Sonora Quest • Gilbert, AZ, United States
Full-time
Last updated: 24 days ago • Promoted
Locum Physician (MD / DO) - Psychiatry - General / Other in Eloy, AZ
LocumJobsNetwork • Eloy, AZ, US
Full-time +1
Last updated: 30+ days ago • Promoted
Locum Physician (MD / DO) - Psychiatry - General / Other in Eloy, AZ
LocumJobsOnline • Eloy, AZ, US
Full-time +1
Last updated: 30+ days ago • Promoted
Travel Surgical Tech - CVOR - $2085.12 / Week
TRS Healthcare • Mesa, AZ, US
Full-time
Last updated: 14 days ago • Promoted
Technical Director
TECHSTAFF of AZ • Coolidge, AZ, US
Full-time
Last updated: 14 days ago • Promoted
DPT / Doctor of Physical Therapy - Inpatient & Outpatient
MLee Healthcare Staffing and Recruiting, Inc • Mesa, AZ, United States
Full-time
Last updated: 4 days ago • Promoted